Discovery may help provide clues for fighting and treating HPV
Yale Cancer Center (YCC) scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus (HPV) infects cells. Their findings, published online today in the journal Cell, may eventually help to broaden the scope of defenses against HPV and provide valuable clues for delivering drugs into cells. HPV is a family of killers. Although there are effective vaccines against these viruses, they still cause about 5% of cancer deaths worldwide, including more than 250,000 women who die of cervical cancer each year.
New Simple Proteins Play Active Role in Cellular Function
Yale scientists have developed simple new proteins almost devoid of chemical diversity that still play a surprisingly active and specific role in cellular function, causing cells to act like cancer cells, they report Aug. 10 in the Proceedings of the National Academy of Sciences.
Long COVID: Skeptics Are Wrong, Researchers Say
WHRY collaborator Akiko Iwasaki, PhD, joins Fiona Lowenstein, editor of “The Long COVID Survival Guide,” to discuss patients who say they’re suffering from Long COVID for as much as two years after their acute phase of the disease. Listen to their discussion as part of "Conversations on Health Care."Source: Community Health Center
Yale Department of Internal Medicine Celebrates Top Female Scientists
Last month, Research.com published the Best Female Scientists in 2022. The results were based on a ranking system which measures the impact of a researcher’s publications by combining the number of papers they have published and how often they are cited by other papers. 623 U.S.-based researchers appeared in list with three women representing the Yale Department of Internal Medicine.
Black Women Excluded from Critical Studies Due to ‘Weathering’
Researchers theorize Black women age earlier and faster as a result of being "weathered" by a lifetime of racial discrimination and race-based stressors. As a result, many Black women are excluded from clinical research studies after reaching age-based milestones earlier.
Randomized Clinical Trial Examines Facilitator-Led Interventions and Self-Administered Tools in Advance Care Planning Engagement
Patient engagement in advance care planning (ACP) is an important and yet challenging goal for clinicians. Several tradeoffs exist between facilitator-led ACP interventions and their required resources compared with self-administered tools.
Provision of Mental Health Services in the Veterans Health Administration: A Nationwide Comparison With Other Providers
On average, Veterans Health Administration (VHA) mental healthcare facilities offer significantly more treatment modalities, specialized services, and dedicated treatment programs than non-VHA facilities, according to a new study by Yale Psychiatry researchers published online in Psychiatric Services.
‘Prime and Spike’ Nasal Vaccine Strategy Helps Combat COVID
The new “prime” and “spike” approach may help prevent breakthrough infections of vaccinated individuals by bolstering immune response within the mucosal lining of the respiratory tract, which are the first cells attacked by COVID-19.Source: YaleNews
Glazer and Omer Are New Members of National Academy of Medicine
Two Yale faculty members, Peter M. Glazer, MD, PhD; and Saad B. Omer, MBBS, MPH, PHD; have been elected to the prestigious National Academy of Medicine, the academy announced today. Founded in 1970 as the Institute of Medicine the National Academy of Medicine (NAM) is one of three academies that make up the National Academies of Sciences, Engineering, and Medicine (the National Academies) in the United States.
Juan Vasquez, MD, Vidya Puthenpura, MD, MHS, FAAP, Awarded Grants to Further Pediatric Cancer Research
Two rising young stars of pediatric cancer research at Yale Cancer Center and Yale School of Medicine were awarded research grants from Hyundai Hope on Wheels program to further their work of improving outcomes and treatment for children diagnosed with cancer.
Ensuring Bone Health for Adolescents Identifying as Transgender
With a grant from Women's Health Research at Yale, Dr. Stuart Weinzimer, in collaboration with Drs. Thomas Carpenter and Christy Olezeski, is using sophisticated methods to obtain a picture of the dynamic process of bone development in adolescents undergoing gender-affirming hormone therapy.
Building Momentum: WHRY's Undergraduate Fellows Advance Women's Health
Women’s Health Research at Yale mentors undergraduate students as well as graduate students and rising junior faculty members to ensure that the next generation of scientists and medical providers fully account for the health needs of women and sex-and-gender differences affecting health. Here are a few examples of what our former undergraduate fellows are up to now.
Fighting Breast and Ovarian Cancer With a Lupus Antibody
After discovering a specific lupus antibody that can penetrate cancer cells and, with a grant from Women's Health Research at Yale, showing it makes cancer cells vulnerable to standard treatments, Dr. Peter Glazer and his colleagues are moving a treatment to clinical trials.
Sex Differences in Gastrointestinal Cancer
With this year's Wendy U. and Thomas C. Naratil Pioneer Award and co-funding from the Yale Cancer Center, Dr. Pamela Kunz is conducting one of the first studies to examine sex differences in treating neuroendocrine neoplasms (NENs), a rare form of cancer often found in the gastrointestinal tract.
Women: What's in a Name?
Today, as our scientific and cultural understanding expands, we have learned that sex and gender are not binary. And, in science, as our knowledge grows so must our efforts to welcome everyone in the identities they bring, and to enhance the precision of our language in adopting terms that value everyone. Even so, we must not forget our history and the descriptive terms that serve us well.
Yale Cancer Center Researchers Awarded Grants by Breast Cancer Research Foundation
The Breast Cancer Research Foundation (BCRF) Scientific Advisory Board and its Board of Directors recently announced its 2022 research grants, including six funded grants at Yale Cancer Center and Smilow Cancer Hospital awarded to Mehra Golshan, MD, MBA, Melinda Irwin, PhD, MPH, Ian Krop, MD, PhD, Lajos Pusztai, MD, DPhil, David Rimm, MD, PhD, and Eric Winer, MD to support their research.