Ross Federman

Ph.D. Student


Yale School of Medicine


Ross is interested in the role that trans-membrane domains play in surface receptor functionality and how this ultimately affects the dynamics of our immune systems. The Traptamer platform provides a novel approach to better understanding the basic principles governing protein-protein interactions within biological membranes. As most aspects of the immune response rely heavily on the activity of integral membrane proteins, a deeper understanding of the interactions of these receptors will afford a more detailed picture of the signaling and activation events responsible for protection against foreign entities as well as pathologies associated with the immune system. Prior to his science career, Ross was a full-time recording artist and touring musician as drummer in the rock band Tally Hall.


Gururaj, C., R. Federman, and A. Chang, Orm proteins integrate multiple signals to maintain sphingolipid homeostasis. J Biol Chem, 2013. 288(28): p. 20453-63.

Heim, E.N., Marston, J.L., Federman, R.S., Edwards, A.P.B., Karabadzhak, A.G., Petti, L.M., Engelman, D.M., and DiMaio, D. (2015) Biologically active LIL proteins built with minimal chemical diversity. Proc. Natl. Acad. Sci. USA 112(34):E4717-25. doi: 10.1073/pnas.1514230112. PMID:26261320. PMCID: PMC4553812.

Federman, R.S., Understanding vaccines: a public imperative. Yale J Biol Med, 2014. 87(4): p. 417-22.

Education & Training

B.S. University of Michigan, Cell and Molecular Biology (2013)