2020
A Preliminary Simulation Study of Dose-Guided Adaptive Radiotherapy Based on Halcyon MV Cone-Beam CT Images With Retrospective Data From a Phase II Clinical Trial
Huang Y, Wang H, Li C, Hu Q, Liu H, Deng J, Li W, Wang R, Wu H, Zhang Y. A Preliminary Simulation Study of Dose-Guided Adaptive Radiotherapy Based on Halcyon MV Cone-Beam CT Images With Retrospective Data From a Phase II Clinical Trial. Frontiers In Oncology 2020, 10: 574889. PMID: 33134173, PMCID: PMC7550711, DOI: 10.3389/fonc.2020.574889.Peer-Reviewed Original ResearchPhase II clinical trialEvaluation patientsClinical trialsAnatomic changesAdaptive radiotherapyPlanning CTPreliminary clinical dataMVCBCT imagesCone-beam CT imagesTarget dose coverageDeformable image registrationClinical dataDose coverageCT imagesPatientsTarget underdosageFractional doseRetrospective dataTumor siteAdaptive plansDoseCTTarget coverageLocal gamma analysisTrials
2015
Intermediate Megavoltage Photon Beams for Improved Lung Cancer Treatments
Zhang Y, Feng Y, Ahmad M, Ming X, Zhou L, Deng J. Intermediate Megavoltage Photon Beams for Improved Lung Cancer Treatments. PLOS ONE 2015, 10: e0145117. PMID: 26672752, PMCID: PMC4682946, DOI: 10.1371/journal.pone.0145117.Peer-Reviewed Original ResearchConceptsDosimetric benefitsPotential dosimetric benefitsTarget coverageComparable target coverageLung cancer patientsLung cancer treatmentBetter target coverageCurrent treatment approachesImproved tumor coverageNormal tissue dosesTumor dose coverageLung cancer radiotherapyAdjacent critical structuresCritical structuresLung doseCancer patientsLung cancerThin patientsLung volumeLung tumorsDose coverageTreatment approachesPatientsReduced dosesTumor coverage
2009
Monte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases
Deng J, Chen Z, Knisely J, Decker R, Chiang V, Nath R. Monte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases. IFMBE Proceedings 2009, 25/1: 13-16. DOI: 10.1007/978-3-642-03474-9_4.Peer-Reviewed Original ResearchSpinal metastasesStereotactic radiosurgeryDose-volume histogramsMean doseAnalytical anisotropic algorithmRisk of recurrenceTarget dose coverageDose distributionPencil beam convolutionSpinal cordDose coverageTarget dosePTV doseTreatment planMetastasisHomogeneity indexDoseRadiosurgeryPBC resultsPatientsTreatment planning systemPatient anatomyCommercial treatment planning systemDose discrepanciesAccurate dose distribution
2001
Incorporate organ motion into MLC leaf sequencing for intensity modulated radiation therapy
Deng J, Guerrero T, Ding M, Jolly J, Pawlicki T, Ma C. Incorporate organ motion into MLC leaf sequencing for intensity modulated radiation therapy. International Journal Of Radiation Oncology • Biology • Physics 2001, 51: 92-93. DOI: 10.1016/s0360-3016(01)01994-0.Peer-Reviewed Original ResearchBreathing patternNormal tissuesRadiation therapyOrgan motionSmaller treatment marginsIMRT plansBreast cancer patientsBreast cancer treatmentAdjacent normal tissuesNormal tissue sparingTarget dose uniformityBreast motionTarget dose conformityBreathing cycleTarget dose distributionCritical structuresHigher complicationsCancer patientsIMRT dosesLow doseTypical breathing patternHigh doseClinical advantagesDose coverage