Publications

• Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution.Hao X, Allgeyer ES, Lee DR, Antonello J, Watters K, Gerdes JA, Schroeder LK, Bottanelli F, Zhao J, Kidd P, Lessard MD, Rothman JE, Cooley L, Biederer T, Booth MJ, Bewersdorf J. Nat Methods. 2021 Jun; 2021 May 31. PMID: 34059828.
• Tissue-specific dynamic codon redefinition in Drosophila.Hudson AM, Szabo NL, Loughran G, Wills NM, Atkins JF, Cooley L. Proc Natl Acad Sci U S A. 2021 Feb 2. PMID: 33500350.
• Drosophila sperm development and intercellular cytoplasm sharing through ring canals do not require an intact fusome.Kaufman RS, Price KL, Mannix KM, Ayers KM, Hudson AM, Cooley L. Development. 2020 Nov 15; 2020 Nov 15. PMID: 33033119.
• HtsRC-Mediated Accumulation of F-Actin Regulates Ring Canal Size During Drosophila melanogaster Oogenesis.Gerdes JA, Mannix KM, Hudson AM, Cooley L. Genetics. 2020 Nov; 2020 Sep 3. PMID: 32883702.
• Proximity labeling reveals novel interactomes in live Drosophila tissue.Mannix KM, Starble RM, Kaufman RS, Cooley L. Development. 2019 Jul 18; 2019 Jul 18. PMID: 31208963.
• Targeted substrate degradation by Kelch controls the actin cytoskeleton during ring canal expansion.Hudson AM, Mannix KM, Gerdes JA, Kottemann MC, Cooley L. Development. 2019 Jan 2; 2019 Jan 2. PMID: 30559276.
• How Primordial Germ Cells Destroy Somatic Signals.Cooley L. Dev Cell. 2017 Jul 24. PMID: 28742996.
• Actin Cytoskeletal Organization in Drosophila Germline Ring Canals Depends on Kelch Function in a Cullin-RING E3 Ligase.Hudson AM, Mannix KM, Cooley L. Genetics. 2015 Nov; 2015 Sep 16. PMID: 26384358.
• The Transgenic RNAi Project at Harvard Medical School: Resources and Validation.Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, Namgyal P, Villalta C, Liu LP, Jiang X, Huan-Huan Q, Wang X, Fujiyama A, Toyoda A, Ayers K, Blum A, Czech B, Neumuller R, Yan D, Cavallaro A, Hibbard K, Hall D, Cooley L, Hannon GJ, Lehmann R, Parks A, Mohr SE, Ueda R, Kondo S, Ni JQ, Perrimon N. Genetics. 2015 Nov; 2015 Aug 28. PMID: 26320097.
• Somatic insulin signaling regulates a germline starvation response in Drosophila egg chambers.Burn KM, Shimada Y, Ayers K, Vemuganti S, Lu F, Hudson AM, Cooley L. Dev Biol. 2015 Feb 15; 2014 Dec 3. PMID: 25481758.
• Antivirulence properties of an antifreeze protein.Heisig M, Abraham NM, Liu L, Neelakanta G, Mattessich S, Sultana H, Shang Z, Ansari JM, Killiam C, Walker W, Cooley L, Flavell RA, Agaisse H, Fikrig E. Cell Rep. 2014 Oct 23; 2014 Oct 16. PMID: 25373896.
• Methods for studying oogenesis.Hudson AM, Cooley L. Methods. 2014 Jun 15; 2014 Jan 17. PMID: 24440745.
• A regulatory network of Drosophila germline stem cell self-renewal.Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, Cooley L, Perrimon N. Dev Cell. 2014 Feb 24. PMID: 24576427.
• Bridging the divide: illuminating the path of intercellular exchange through ring canals.McLean PF, Cooley L. Fly (Austin). 2014; 2013 Nov 8. PMID: 24406334.
• Determination of two-photon photoactivation rates of fluorescent proteins.Hartwich TM, Subach FV, Cooley L, Verkhusha VV, Bewersdorf J. Phys Chem Chem Phys. 2013 Sep 28. PMID: 23852136.
• Protein equilibration through somatic ring canals in Drosophila.McLean PF, Cooley L. Science. 2013 Jun 21; 2013 May 23. PMID: 23704373.
• Expression of Ixodes scapularis antifreeze glycoprotein enhances cold tolerance in Drosophila melanogaster.Neelakanta G, Hudson AM, Sultana H, Cooley L, Fikrig E. PLoS One. 2012; 2012 Mar 13. PMID: 22428051.
• Intercellular protein movement in syncytial Drosophila follicle cells.Airoldi SJ, McLean PF, Shimada Y, Cooley L. J Cell Sci. 2011 Dec 1; 2011 Dec 1. PMID: 22135360.
• Reversible response of protein localization and microtubule organization to nutrient stress during Drosophila early oogenesis.Shimada Y, Burn KM, Niwa R, Cooley L. Dev Biol. 2011 Jul 15; 2011 Apr 23. PMID: 21570389.
• Drosophila Kelch functions with Cullin-3 to organize the ring canal actin cytoskeleton.Hudson AM, Cooley L. J Cell Biol. 2010 Jan 11. PMID: 20065088.
• Mononuclear muscle cells in Drosophila ovaries revealed by GFP protein traps.Hudson AM, Petrella LN, Tanaka AJ, Cooley L. Dev Biol. 2008 Feb 15; 2007 Dec 4. PMID: 18199432.
• Phylogenetic, structural and functional relationships between WD- and Kelch-repeat proteins.Hudson AM, Cooley L. Subcell Biochem. 2008. PMID: 18925367.
• Jagunal is required for reorganizing the endoplasmic reticulum during Drosophila oogenesis.Lee S, Cooley L. J Cell Biol. 2007 Mar 26. PMID: 17389229.
• Exploring strategies for protein trapping in Drosophila.Quiñones-Coello AT, Petrella LN, Ayers K, Melillo A, Mazzalupo S, Hudson AM, Wang S, Castiblanco C, Buszczak M, Hoskins RA, Cooley L. Genetics. 2007 Mar; 2006 Dec 18. PMID: 17179094.
• The Ovhts polyprotein is cleaved to produce fusome and ring canal proteins required for Drosophila oogenesis.Petrella LN, Smith-Leiker T, Cooley L. Development. 2007 Feb; 2007 Jan 10. PMID: 17215303.
• Illuminating the role of caspases during Drosophila oogenesis.Mazzalupo S, Cooley L. Cell Death Differ. 2006 Nov; 2006 Mar 10. PMID: 16528381.
• Drosophila myosin V is required for larval development and spermatid individualization.Mermall V, Bonafé N, Jones L, Sellers JR, Cooley L, Mooseker MS. Dev Biol. 2005 Oct 1. PMID: 16126191.
• Flytrap, a database documenting a GFP protein-trap insertion screen in Drosophila melanogaster.Kelso RJ, Buszczak M, Quiñones AT, Castiblanco C, Mazzalupo S, Cooley L. Nucleic Acids Res. 2004 Jan 1. PMID: 14681446.
• Drosophila filamin is required for follicle cell motility during oogenesis.Sokol NS, Cooley L. Dev Biol. 2003 Aug 1. PMID: 12885568.
• Arp2/3-dependent pseudocleavage [correction of psuedocleavage] furrow assembly in syncytial Drosophila embryos.Stevenson V, Hudson A, Cooley L, Theurkauf WE. Curr Biol. 2002 Apr 30. PMID: 12007413.
• Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila.Tekotte H, Berdnik D, Török T, Buszczak M, Jones LM, Cooley L, Knoblich JA, Davis I. Dev Biol. 2002 Apr 15. PMID: 11944946.
• Mutations in the midway gene disrupt a Drosophila acyl coenzyme A: diacylglycerol acyltransferase.Buszczak M, Lu X, Segraves WA, Chang TY, Cooley L. Genetics. 2002 Apr. PMID: 11973306.
• Control of DNA replication and chromosome ploidy by geminin and cyclin A.Mihaylov IS, Kondo T, Jones L, Ryzhikov S, Tanaka J, Zheng J, Higa LA, Minamino N, Cooley L, Zhang H. Mol Cell Biol. 2002 Mar. PMID: 11865064.
• Drosophila Kelch regulates actin organization via Src64-dependent tyrosine phosphorylation.Kelso RJ, Hudson AM, Cooley L. J Cell Biol. 2002 Feb 18; 2002 Feb 18. PMID: 11854310.
• SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila.Zallen JA, Cohen Y, Hudson AM, Cooley L, Wieschaus E, Schejter ED. J Cell Biol. 2002 Feb 18; 2002 Feb 18. PMID: 11854309.
• A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex.Hudson AM, Cooley L. J Cell Biol. 2002 Feb 18; 2002 Feb 18. PMID: 11854308.
• Understanding the function of actin-binding proteins through genetic analysis of Drosophila oogenesis.Hudson AM, Cooley L. Annu Rev Genet. 2002; 2002 Jun 11. PMID: 12429700.
• Comparative aspects of animal oogenesis.Matova N, Cooley L. Dev Biol. 2001 Mar 15. PMID: 11237461.
• Filamins as integrators of cell mechanics and signalling.Stossel TP, Condeelis J, Cooley L, Hartwig JH, Noegel A, Schleicher M, Shapiro SS. Nat Rev Mol Cell Biol. 2001 Feb. PMID: 11252955.
• Eggs to die for: cell death during Drosophila oogenesis.Buszczak M, Cooley L. Cell Death Differ. 2000 Nov. PMID: 11139280.
• Physical and genetic interaction of filamin with presenilin in Drosophila.Guo Y, Zhang SX, Sokol N, Cooley L, Boulianne GL. J Cell Sci. 2000 Oct. PMID: 10984440.
• The kelch repeat superfamily of proteins: propellers of cell function.Adams J, Kelso R, Cooley L. Trends Cell Biol. 2000 Jan. PMID: 10603472.
• Drosophila quail, a villin-related protein, bundles actin filaments in apoptotic nurse cells.Matova N, Mahajan-Miklos S, Mooseker MS, Cooley L. Development. 1999 Dec. PMID: 10572041.
• Drosophila filamin encoded by the cheerio locus is a component of ovarian ring canals.Sokol NS, Cooley L. Curr Biol. 1999 Nov 4. PMID: 10556087.
• Ecdysone response genes govern egg chamber development during mid-oogenesis in Drosophila.Buszczak M, Freeman MR, Carlson JR, Bender M, Cooley L, Segraves WA. Development. 1999 Oct. PMID: 10498692.
• Drosophila ring canal growth requires Src and Tec kinases.Cooley L. Cell. 1998 Jun 12. PMID: 9635420.
• Apoptosis in late stage Drosophila nurse cells does not require genes within the H99 deficiency.Foley K, Cooley L. Development. 1998 Mar. PMID: 9463354.
• Drosophila fascin mutants are rescued by overexpression of the villin-like protein, quail.Cant K, Knowles BA, Mahajan-Miklos S, Heintzelman M, Cooley L. J Cell Sci. 1998 Jan. PMID: 9405306.
• Drosophila kelch is an oligomeric ring canal actin organizer.Robinson DN, Cooley L. J Cell Biol. 1997 Aug 25. PMID: 9265647.
• Using explicitly represented biological relationships for database navigation and searching via the World-Wide Web.Panzer S, Cooley L, Miller PL. Comput Appl Biosci. 1997 Jun. PMID: 9183533.
• Examination of the function of two kelch proteins generated by stop codon suppression.Robinson DN, Cooley L. Development. 1997 Apr. PMID: 9118811.
• Formation of the Drosophila ovarian ring canal inner rim depends on cheerio.Robinson DN, Smith-Leiker TA, Sokol NS, Hudson AM, Cooley L. Genetics. 1997 Apr. PMID: 9093858.
• Genetic analysis of the actin cytoskeleton in the Drosophila ovary.Robinson DN, Cooley L. Annu Rev Cell Dev Biol. 1997. PMID: 9442871.
• Stable intercellular bridges in development: the cytoskeleton lining the tunnel.Robinson DN, Cooley L. Trends Cell Biol. 1996 Dec. PMID: 15157506.
• Single amino acid mutations in Drosophila fascin disrupt actin bundling function in vivo.Cant K, Cooley L. Genetics. 1996 May. PMID: 8722779.
• Oogenesis: variations on a theme.Cooley L. Dev Genet. 1995. PMID: 7758241.
• Cytoskeletal functions during Drosophila oogenesis.Cooley L, Theurkauf WE. Science. 1994 Oct 28. PMID: 7939713.
• Intercellular cytoplasm transport during Drosophila oogenesis.Mahajan-Miklos S, Cooley L. Dev Biol. 1994 Oct. PMID: 7958404.
• The villin-like protein encoded by the Drosophila quail gene is required for actin bundle assembly during oogenesis.Mahajan-Miklos S, Cooley L. Cell. 1994 Jul 29. PMID: 8044841.
• Morphogenesis of Drosophila ovarian ring canals.Robinson DN, Cant K, Cooley L. Development. 1994 Jul. PMID: 7925006.
• The specialized cytoskeleton of the Drosophila egg chamber.Knowles BA, Cooley L. Trends Genet. 1994 Jul. PMID: 8091503.
• Profilin mutations disrupt multiple actin-dependent processes during Drosophila development.Verheyen EM, Cooley L. Development. 1994 Apr. PMID: 7600952.
• Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension.Cant K, Knowles BA, Mooseker MS, Cooley L. J Cell Biol. 1994 Apr. PMID: 8163553.
• Looking at oogenesis.Verheyen E, Cooley L. Methods Cell Biol. 1994. PMID: 7707970.
• kelch encodes a component of intercellular bridges in Drosophila egg chambers.Xue F, Cooley L. Cell. 1993 Mar 12. PMID: 8453663.
• chickadee encodes a profilin required for intercellular cytoplasm transport during Drosophila oogenesis.Cooley L, Verheyen E, Ayers K. Cell. 1992 Apr 3. PMID: 1339308.