Colorectal Cancer and Women
Colon cancer has been undergoing a similar subdivision. Researchers have known for years that colorectal cancer is the third most common cancer diagnosis in the United States and the second leading cause of cancer-related deaths. The National Cancer Institute estimates 149,500 new cases in 2021 and 53,000 deaths.
Sex-specific Immune Response in COVID-19 Linked to Cellular Metabolism
Researchers studying COVID-19 patients have found a metabolic pathway that is highly correlated with immune responses only in male patients, a group known to be more likely to suffer severe cases and die of the disease, representing a potential target for therapeutic intervention.Source: Yale News
How Your Help Can Fund the Next Discovery in Women's Health Research
If the challenges of the past year have taught us anything, it is that we must continue working to understand all that we can about health and disease. And when it comes to sex and gender, we should not wait for the next crisis before addressing these critical components of our health.
Better Science, Better Lives: Women's Health Research at Yale is Working for You
Across the country, it’s becoming clearer every day: We must study the health of women. We must study the influence of sex-and-gender differences on health. And it’s time for all aspects of medical research and practice to embrace this change.
Breaking it Down: How the Chemistry of Digestion is Uncovering Sex-Specific Causes of Colon Cancer
A new technology called metabolomics allows researchers to explore the small chemicals formed and used during digestion as a window into the formation of diseases such as colon cancer, seeking early warning signs and potent tactics for prevention.
Can Digestive Chemistry Uncover Sex-Specific Causes of Colon Cancer?
Dr. Caroline Helen Johnson received this year’s Wendy U. and Thomas C. Naratil Pioneer Award and co-funding from the Yale Cancer Center to explore hormones and environmental factors related to metabolite production (such as sugars and amino acids) and beneficial bacteria that live in the colon as possible sources of gender difference.
Women’s Health Research at Yale funds studies on colon cancer, infections in pregnancy, and domestic violence
“Through our competitive peer review process, these three studies stood out as extremely promising opportunities to improve and even save lives,” said Dr. Carolyn M. Mazure, director of WHRY. “With these new grants, we continue to expand a broad scope of existing work to focus on questions vital to the health and well-being of millions of women, men, and children.”
Yale Department of Internal Medicine Celebrates Top Female Scientists
Last month, Research.com published the Best Female Scientists in 2022. The results were based on a ranking system which measures the impact of a researcher’s publications by combining the number of papers they have published and how often they are cited by other papers. 623 U.S.-based researchers appeared in list with three women representing the Yale Department of Internal Medicine.
Yale Study Seeks to Understand Neurobiology Underlying Bipolar Disorder Vs. Major Depressive Disorder
Yale scientists, including Sophie Holmes, PhD; Ruth Asch, PhD; and Irina Esterlis, PhD, used positron emission tomography to understand the neurobiology underlying bipolar disorder versus major depressive disorder. The findings were published in Biological Psychiatry.Source: Biological Psychiatry
Collaboration on NIH grant between Sullivan, Nez Henderson will create program to help Indigenous women experiencing domestic violence quit smoking
Tami Sullivan, PhD, associate professor of psychiatry at Yale School of Medicine, and Patricia Nez Henderson, MD, MPH, vice president for the Black Hills Center for American Indian Health (BHCAIH) and the first Indigenous woman to graduate from Yale School of Medicine, have been awarded a grant from the National Institutes of Health (NIH) to pilot a mindfulness-based, culturally-tailored smoking cessation intervention for Indigenous women who experience intimate partner violence (IPV).
A Randomized Clinical Trial to Evaluate an Atrial Fibrillation Stroke Prevention Shared Decision‐Making Pathway
Oral anticoagulation (OAC) reduces stroke and disability in atrial fibrillation (AF) but is underutilized. Researchers, including Julio Nunes, MD, first-year resident, evaluated the effects of a novel patient‐clinician shared decision‐making (SDM) tool in reducing OAC patient's decisional conflict as compared to usual care.Source: Journal of the American Heart Association
Does Street Outreach Engage Its Intended Target Population? Clinical Experience in the Veteran’s Health Administration Homeless Service Programs
Emma Lo, MD; Jack Tsai, PhD; Elina Stefanovics, PhD; and Robert Rosenheck, MD, are co-authors of a paper in Psychiatric Quarterly that found veterans engaged through clinical street outreach programs reported substantially more days of unsheltered homelessness than a clinic-referred group of veterans.Source: Psychiatric Quarterly
Yale Study Revises Understanding of How the Brain Processes and Responds to Rewards
A new Yale study of neuron activity in the brain has revised scientists’ understanding of how the brain processes and responds to rewards. Marina Picciotto, PhD, Charles B. G. Murphy Professor of Psychiatry and Professor in the Child Study Center, of Neuroscience and of Pharmacology, is the study’s senior author.
Moderating the Relationship Between Ulcerative Colitis and Crohn’s Disease and Symptoms of PTSD
Alexandra Fuss, PhD, assistant professor of psychiatry, is first author of a paper in Journal of Clinical Gastroenterology that examines whether inflammatory bowel disease (IBD) patients endorse clinically significant symptoms of post-traumatic stress disorder (PTSD), and tests whether remission status and remission expectations effectively moderate the relationship between endorsements of PTSD symptoms and aspects of IBD.Source: Journal of Clinical Gastroenterology
Ketamine infusions improve symptoms of depression, anxiety and suicidal ideation, study says
People who got intravenous ketamine at three private ketamine infusion clinics had "significant improvement" in symptoms of depression, anxiety and suicidal ideation, according to a new study by Gerard Sanacora, PhD, MD George D. and Esther S. Gross Professor of Psychiatry, published in the Journal of Clinical Psychiatry.Source: CNN