Lieping Chen, PhD, wins prestigious 2017 Warren Alpert Prize
Lieping Chen, Ph.D., co-director of the Cancer Immunology Program at Yale Cancer Center and United Technologies Corporation Professor in Cancer Research and professor of immunobiology, of dermatology and of medicine at Yale School of Medicine, has been presented with the 2017 Warren Alpert Foundation Prize for transformative discoveries in the field of cancer immunology.
Lieping Chen among five scientists recognized for discoveries in cancer immunology
Lieping Chen, Ph.D., the United Technologies Corporation Professor in Cancer Research and professor of immunobiology, of dermatology, and of medicine, is one of five scientists to receive the 2017 Warren Alpert Foundation Prize.
Innovation to Impact: Dr. Lieping Chen and NextCure
Dr. Lieping Chen is a pioneer in the field of immuno-oncology and his discoveries have led to life-saving drugs for cancer patients. Now, with the support of the Yale Office of Cooperative Research, Dr. Chen has launched a startup—NextCure—that is poised to lead to even more breakthrough treatments.
New Germantown biotech nets $67 million from investors
New Germantown biotech nets $67 million from investors, including Eli Lilly and Pfizer to fund research and development in Dr. Lieping Chen’s laboratory. Immuno-oncology has attracted growing notice over the past few years, but only a handful of drugs in the nascent field have been approved for broad public use. Two of those drugs leading the charge — Keytruda and Opdivo — target the PD-1/PD-L1 pathway that Chen is credited with innovating. Keytruda, manufactured by Merck, made headlines last year when former president Jimmy Carter said he was using it to treat cancerous tumors in his brain and liver. Carter said in December that he is cancer-free.Source: The Washington Post
Yale Study: Use of a Model Maturity Matrix to Build a Quality Improvement Infrastructure for Psychiatric Care
Luming Li, MD, Assistant Professor of Psychiatry, is senior author of a paper published in Psychiatric Services that proposes the use of a quality improvement maturity matrix to serve as both an implementation strategy and a self-assessment measure to strategically guide development of infrastructure to improve the safety and quality of behavioral health care.Source: Psychiatric Services
Elena Gracheva is a finalist of the 2020 Blavatnik National Awards for Young Scientists
Dr. Elena Gracheva, an Associate Professor of Cellular & Molecular Physiology and of Neuroscience, is a 2020 Finalists of the prestigious Blavatnik National Awards for Young Scientists, the world’s largest unrestricted prize for early-career scientists.Source: Elena Gracheva is a finalist of the 2020 Blavatnik National Awards for Young Scientists
Yale Researchers Find Where Stress Lives
Yale researchers have found a neural home of the feeling of stress people experience, an insight that may help people deal with the debilitating sense of fear and anxiety that stress can evoke, Yale researchers report May 27 in the journal Nature Communications.
WHRY Funds Studies on Stroke, Endometrial Cancer, and Addiction to Opioids
Women’s Health Research at Yale today announced funding for three studies investigating sex differences in stroke, endometrial cancer, and alternate pain relief for women recovering from past opioid use who are giving birth via cesarean section.
Updates in Consultation-Liaison Psychiatry: 2019
Paula Zimbrean, MD, Associate Professor of Psychiatry; Walter Luchsinger, MD, Addiction Psychiatry Fellow; and Jordan Rosen, MD, Consultation-Liaison Psychiatry Fellow, are co-authors of a paper published in Psychosomatics that identifies the 10 most important manuscripts for clinical practice in consultation-liaison psychiatry from 2019.Source: Psychosomatics
New Imaging Tool Helps Researchers See Extent of Alzheimer’s Early Damage
New imaging technology allows scientists to see the widespread loss of brain synapses in early stages of Alzheimer’s disease, a finding that one day may aid in drug development, according to a new Yale University study.Source: Yale News
Courses of Suicidal Ideation Among Military Veterans in Residential Treatment for Posttraumatic Stress Disorder
Noelle B. Smith, PhD, Assistant Clinical Professor of Psychiatry; Rani Hoff, PhD, Professor of Psychiatry; and Ilan Harpaz-Rotem, PhD, are co-authors of a study published in Depression & Anxiety that examines the prevalence and correlates of four courses of suicidal ideation among veterans receiving residential treatment for posttraumatic stress disorder.Source: Depression & Anxiety
Psilocybin-Assisted Therapy of Major Depressive Disorder Using Acceptance and Commitment Therapy as a Therapeutic Frame
Jordan Sloshower, MD, MSc, Research Fellow in Addiction Psychiatry, is the first author of a paper published in Journal of Contextual Behavioral Science that tracks the psychedelic assisted therapy of depression with the integration of Acceptance and Commitment Therapy.Source: Journal of Contextual Behavioral Science
Delayed Homelessness After Military Discharge: Examination of a Sleeper Effect
Jack Tsai, PhD, Adjunct Associate Professor of Psychiatry, and Robert Pietrzak, PhD, Associate Professor of Psychiatry and Public Health, are the first and senior authors, respectively, published in American Journal of Preventive Medicine that examines the “sleeper effect” of longer discharge-to-homelessness periods for veterans including service in the Vietnam War, younger age at military discharge, and chronic medical conditions, depression, and alcohol use problems.Source: American Journal of Preventive Medicine
Ni Feng receives a 2020 Warren Alpert Distinguished Scholar Award
Ni Fend, a postdoctoral researcher in Elena Gracheva's lab, has become a 2020 Warren Alpert Distinguished Scholar. Her project "Hanging in the Balance: Fluid Homeostasis in Hibernation" aims to reveal fundamental knowledge about how hibernation enables some species to survive over an entire winter without water. This project will use the thirteen-lined ground squirrel as a model system to dissect and manipulate the neural circuits that regulate fluid balance across torpor and arousal states during hibernation.Source: Ni Feng receives a 2020 Warren Alpert Distinguished Scholar award
Krystal Co-Author of NEJM Article That Tracks Symptom Improvement in Patients With Schizophrenia
Patients with schizophrenia demonstrated improvement on a scale used to measure symptom severity after taking a drug being tested in a clinical trial, according to an article published online in the New England Journal of Medicine and co-authored by John H. Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and Chair of the Yale Department of Psychiatry at Yale School of Medicine
Deadlier Colon Cancer Develops Differently in Women and Men
WHRY-affiliated researchers have found that colon cancer tumor cells produce energy for growth differently in women and men, and that this difference is associated with a more aggressive form of tumor growth with a higher incidence in women.