Functional brain connectivity
Our school-aged Autism Center of Excellence (ACE) studies examine brain connectivity in school-age children with ASD. Children with ASD, children who have an older sibling with ASD, and typically developing children are all eligible for our study examining brain connectivity in school-aged children.
Participation will include one MRI, assessments of social, adaptive, cognitive, and language development and studies of attention requiring watching videos and listening to sounds.
The MRI scans take place at 300 Cedar St., New Haven, CT. All other visits will occur at our clinic at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking.
This ACE project will examine biological differences in early neurodevelopment in pairs of brothers where either one or both brothers are diagnosed with ASD. The goal is to determine the biological and genetic markers that are linked with functional brain connectivity and presentation of autism symptoms.
Through this study, a small piece of skin on the arm the size of a grain of rice will be obtained from all participants. For details of the biopsy procedure, please click here. Children will also undergo a magnetic resonance imaging (MRI) scan and will complete clinical assessments and eye-tracking studies.
The skin biopsy takes place at Yale Center for Clinical Investigations, Hospital Research Unit (HRU) located on the 10th floor of Yale New Haven Hospital, New Haven, CT. The MRI scans take place at 300 Cedar St., New Haven, CT. Diagnostic and research assessment take place at the SANA Lab at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking.