Oligonucleotide Synthesis Pricing
Rates as of 7/1/2023
| Service | Description | Yale Cost per sample* | Non-Yale Cost per sample* | |
|---|---|---|---|---|
| Unpurified DNA | ||||
| 25 nanomole scale-96-well PLATE for >47 oligos (DESALTED, ≤65 bases/un-modified ONLY!) (Yield of final product will be <25 nmoles) | residue charge | $0.21 | $0.26 | |
| 25 nanomole scale-TUBES (DESALTED, ≤65 bases/un-modified ONLY!) (Yield of final product will be <25 nmoles) | residue charge | $0.22 | $0.29 | |
| 100 nanomole scale-96-well PLATE for >47 oligos (DESALTED, 1-119 bases with 3' dA, dG, dC or dT) (Yield of final product will be <100 nmoles) | residue charge | $0.26 | $0.33 | |
| 100 nanomole scale-TUBES (DESALTED, 1-119 bases with 3' dA, dG, dC or dT) (Yield of final product will be <100 nmoles) | residue charge | $0.29 | $0.35 | |
| 40 nanomole scale (>119 bases and/or modified) (Yield of final product will be <40 nmoles) | residue charge | $0.55 | $0.68 | |
| 200 nanomole scale (Yield of final product will be <200 nmoles) | residue charge | $0.85 | $1.11 | |
| 1.0 Micromole Scale (Yield of final product will be < 1.0 umole) | residue charge | $2.17 | $2.70 | |
| RNA/2'-O-Methyl RNA | ||||
| 1.0 Micromole Scale (Yield of final product will be <1.0 umole) | residue charge | $16.75 | $20.65 | |
| Purified DNA | ||||
| Cartridge Purified DNA-all synthesis scales | Surcharge per oligo | $17.00 | $25.00 | |
| RP-HPLC/All Synthesis Scales (< 100-mers - DNA only) | Surcharge per oligo | $57.00 | $70.00 | |
| 40 nanomole PAGE purification (surcharge per Oligo) | Surcharge per oligo | $50.00 | $62.00 | |
| 200 nanomole PAGE purification (surcharge per Oligo) | Surcharge per oligo | $85.00 | $105.00 | |
| 1.0 umole PAGE purification (surcharge per Oligo) | Surcharge per oligo | $275.00 | $340.00 | |
| Purified RNA | ||||
| 2' Deprotection/Purification | Surcharge per oligo | $56.00 | $70.00 | |
Consulting |
Consulting Charge (per hour) | $30.00 | $51.75 | |
| Custom Processing | Pooling, Normalization, Special Packaging (surcharge per oligo) | Request A Quote | - | |
| Custom Processing | Custom synthesizer programming (surcharge per oligo) | Request A Quote | - | |
*E-mail oligos@yale.edu for volume discounts (>47 oligos) and for-profit company pricing.