Determining the cost of a modified oligo begins with selecting the scale of the synthesis, then determining the appropriate per residue charges.
- A normal DNA per-residue charge is used for the modified residues unless those modifiers are RNA or 2'-O- methyl RNA.
Most of our specialty reagents are ordered from Glen Research. Glen offers only 0.2 micromole and 1.0 micromole columns for initiating syntheses with 3' modified residues.
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