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Figure 5b, heat map overlay of cocaine-regulated proteomes in male vs. female mice, from Lopez et al. (2021).

Figure 2b from Rich et J. Neurosci. (2016) publication and CPDD (2015) poster.  Identification of signaling pathways regulated by cocaine-associated memory extinction and reconsolidation. Phosphoproteomic analysis from tissue collected following memory manipulations reveals phosphopeptides regulated in the same direction by extinction vs reconsolidation.


View the Yale/NIDA Neuroproteomics Center Posters and Abstracts Archives

This Special Issue will contain research and review articles that cover whole proteome analysis, comparative proteomics, protein structure/function, protein post-translational modifications, protein:ligand and protein:protein interactions within normal and diseased neurological tissues. Since the huge level of cellular and sub-cellular heterogeneity in the CNS is the greatest obstacle impeding progress towards understanding the adaptive molecular changes that underlie drug addiction and that occur in other neurological diseases, we are especially interested in manuscripts that describe the use of laser capture microscopy, fluorescence cytometry-related, and immuno-affinity technologies in conjunction with transgenic and viral methods to isolate and study neural cell type- and organelle-specific proteomes