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Yale/NIDA Neuroproteomics Center Project Investigators

Name Department Institution Website Project Title
James Bibb Psychiatry
University of Alabama at Birmingham
James A. Bibb, Ph.D. Profiling the Nucleus Accumbens Proteome in A Rodent Model of Intestinal Inflammation: Implications for Addictive Disorders
Thomas Biederer Neurology Yale University Thomas Biederer, Ph.D.
Identification and Analysis of Synapse-Organizing Complexes in Addiction-Relevant Brain Regions
Sreeganga Chandra Neurology Yale University Sreeganga Chandra, Ph.D. Neuronal Substrates Required for Synapse Maintenance
Christopher Cowan
Neuroscience, Psychiatry
Medical University of South Carolina
Christopher Cowan, Ph.D.
Analysis of ROS-Sensitive HDAC5 PTMs and Identification of HDAC5 Repressor Complexes in Rats Self-Administering Cocaine or Heroin
Pietro De Camilli Cell Biology Yale University Pietro De Camilli, M.D. Membrane Traffic and Lipid Dynamics in Neuronal Function
Lakshmi Devi Pharmacology & Systems Therapeutics Mount Sinai School of Medicine Lakshmi Devi, Ph.D. Identification of Novel Modulators of Opioid Receptor Signaling During Drug Addiction
Ronald Duman
Psychiatry, Neuroscience Yale University Ronald Duman, Ph.D.
Sex and Temporal Differences in Stress-induced Proteome Changes in Brain Reward Regions: Impact on Substance Abuse
Profiling Synaptic Proteome and Post-transcriptional Modifications Following Ketamine Treatment: Implications in Drug Addiction
John Elsworth
Psychiatry Yale University
John Elsworth, Ph.D.
Age-dependent Protection and Vulnerability to Drugs of Abuse in Nonhuman Primates
William N. Green Neurobiology University of Chicago William N. Green, Ph.D. Proteomic Assays of Nicotine-induced Golgi Fragments and Changes in Glycosylation
Leonard K. Kaczmarek Pharmacology, Cellular and Molecular Physiology Yale University Leonard K. Kaczmarek, Ph.D. Modulation of Potassium Channels by Protein Phosphorylation and Interacting Auxiliary Proteins
Paul J. Kenny Pharmacology, and Systems Therapeutics Mount Sinai School of Medicine Paul J. Kenny, Ph.D. Mechanisms by Which Tcf7l2 Controls Addiction-relevant Gene Expression in the Habenula
Drew Kiraly
Psychiatry, Neuroscience
Mount Sinai School of Medicine
Drew Kiraly, M.D.; Ph.D.
Neuroimmune and Microbiome Effects on Limbic Reward Structures in Models of Substance Use Disorders
Michael R. Koelle Molecular Biophysics & Biochemistry Yale University
Michael R. Koelle, Ph.D. Proteomic Analysis of Complexes formed by the Neural G Protein Gαo
Ken Mackie Psychological and Brain Sciences Indiana University Ken Mackie, M.D. Cannabinoid Interactions with the Developing Brain
Stephen J. Moss
Department of Neuroscience
Tufts University
Stephen J. Moss
Analyzing the Effects of Benzodiazepines on the Structure and Phosphorylation of Type A γ-Aminobutyric Acid Receptors
Angus Nairn Psychiatry Yale University Angus Nairn, Ph.D. Regulation of Synaptic Structure and Function by Drugs of Abuse
Eric Nestler Chair, Neuroscience Mount Sinai School of Medicine Eric Nestler, Ph.D., M.D.
Proteomic Profiling of Drug-induced Alterations to the Brain Reward System Underlying Addiction
Marina Picciotto Psychiatry, Pharmacology, Neurobiology Yale University Marina Picciotto, Ph.D. Proteomics of Altered Signaling in Nicotine Addiction
Stephen Strittmatter

Neurobiology, Neurology

Yale University Stephen Strittmatter, M.D., Ph.D. Proteomic Basis for Chronic Anatomical Plasticity of Synapses
Jane Taylor Psychiatry Yale University Jane Taylor, Ph.D. Proteomic Analysis of Cellular Alterations Associated with Drug-Induced Impairments in Decision-Making, Mnemonic Processes and Relapse Behaviors
Susumu Tomita Cellular and Molecular Physiology
Yale University Susumu Tomita, Ph.D. Identification of Altered Phosphorylation Signaling in Neurotransmission
Mary Torregrossa Psychiatry University of Pittsburgh Mary Torregrossa, Ph.D. Identifying Changes in Protein Signaling that Regulate Substance Use Vulnerability, Craving, and Relapse.
Joachim de Klerk Uys
Cell and Molecular Pharmacology
Medical University of South Carolina
Joachim de Klerk Uys, Ph.D.
Quantitative Proteomic Analysis of the Glutathionome in Heroin Addiction.