2012
Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice
Smith K, Williamson TL, Schwartz ML, Vaccarino FM. Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. Brain Research 2012, 1460: 12-24. PMID: 22578469, PMCID: PMC3361544, DOI: 10.1016/j.brainres.2012.04.002.Peer-Reviewed Original ResearchConceptsFibroblast growth factor receptorHuman GFAP promoterInner granule cell layerDKO miceGranule cell numberGranule cell progenitorsRadial glial stem cellsMidline glial structuresImpaired motor coordinationCerebellar sizeGranule cell layerDouble knockout miceGlial precursor cellsGlial stem cellsCell numberGranule neuron precursorsGrowth factor receptorGABA interneuronsGranule cell migrationCerebral cortexExternal granular layerMolecular layerMotor coordinationGranule cellsKnockout mice
2009
Precursors with Glial Fibrillary Acidic Protein Promoter Activity Transiently Generate GABA Interneurons in the Postnatal Cerebellum
Silbereis J, Cheng E, Ganat YM, Ment LR, Vaccarino FM. Precursors with Glial Fibrillary Acidic Protein Promoter Activity Transiently Generate GABA Interneurons in the Postnatal Cerebellum. Stem Cells 2009, 27: 1152-1163. PMID: 19418461, PMCID: PMC2903623, DOI: 10.1002/stem.18.Peer-Reviewed Original ResearchConceptsCerebellar white matterWhite matterGFAP/Inducible Cre recombinationMolecular layerGlial cell typesNSC/NPCsGABA interneuronsGFAP promoter activityGAD-67GABAergic interneuronsGlial cellsIntact cerebellumNeurogenic potentialCerebellar cortexCerebellar interneuronsInhibitory factorPostnatal cerebellumInterneuronsNeural stemProgenitor cellsDifferent neuronsCerebellumCerebellar developmentCre recombination
2002
Fibroblast Growth Factor 2 Is Necessary for the Growth of Glutamate Projection Neurons in the Anterior Neocortex
Korada S, Zheng W, Basilico C, Schwartz ML, Vaccarino FM. Fibroblast Growth Factor 2 Is Necessary for the Growth of Glutamate Projection Neurons in the Anterior Neocortex. Journal Of Neuroscience 2002, 22: 863-875. PMID: 11826116, PMCID: PMC6758485, DOI: 10.1523/jneurosci.22-03-00863.2002.Peer-Reviewed Original ResearchConceptsCerebral cortexParietal cortexAnterior cerebral cortexGlutamatergic pyramidal neuronsGABA receptor agonistsGlutamatergic neuronal populationsDuration of sleepAnterior cortical regionsBasic fibroblast growth factorCell numberNull mutant miceGranule cell numberFibroblast growth factor-2Fibroblast growth factorGABA interneuronsGrowth factor 2Fgf2-/- micePyramidal neuronsInhibitory neurotransmissionProjection neuronsAnterior neocortexReceptor agonistPyramidal cellsOccipital cortexNeuronal populations