2024
W31 The Impact of Tobacco Use on Liver-Related Morbidity in Patients With Cirrhosis
Haque L, Fiellin D, Bryant K, Edelman E, Justice A, Lim J, Re V, Marshall B, Taddei T, Tate J, Tetrault J, Williams E, McGinnis K. W31 The Impact of Tobacco Use on Liver-Related Morbidity in Patients With Cirrhosis. Drug And Alcohol Dependence 2024, 260: 110649. DOI: 10.1016/j.drugalcdep.2023.110649.Peer-Reviewed Original ResearchThe MATE Act: Progress for substance use education, but is checking a box enough?
Morford K, Tetrault J, Fiellin D. The MATE Act: Progress for substance use education, but is checking a box enough? Journal Of General Internal Medicine 2024, 39: 1496-1498. PMID: 38308156, PMCID: PMC11169132, DOI: 10.1007/s11606-024-08652-7.Peer-Reviewed Original Research
2022
Association Between Alcohol Use Disorder and Receipt of Direct-Acting Antiviral Hepatitis C Virus Treatment
Haque L, Fiellin D, Tate J, Esserman D, Bhattacharya D, Butt A, Crystal S, Edelman E, Gordon A, Lim J, Tetrault J, Williams E, Bryant K, Cartwright E, Rentsch C, Justice A, Re V, McGinnis K. Association Between Alcohol Use Disorder and Receipt of Direct-Acting Antiviral Hepatitis C Virus Treatment. JAMA Network Open 2022, 5: e2246604. PMID: 36515952, PMCID: PMC9856353, DOI: 10.1001/jamanetworkopen.2022.46604.Peer-Reviewed Original ResearchConceptsCurrent alcohol use disorderLow-risk drinkingAlcohol use disorderVeterans Health AdministrationHistory of AUDDAA treatmentAlcohol use categoriesAUD historyCohort studyRisk drinkingUse disordersDirect acting antiviral (DAA) treatmentAlcohol Use Disorders Identification Test-Consumption (AUDIT-C) questionnaireHepatitis C virus infectionHepatitis C virus (HCV) treatmentCox proportional hazards regressionC virus infectionC virus treatmentProportional hazards regressionTenth Revision diagnosisAUDIT-C questionnaireInternational Statistical ClassificationRelated Health ProblemsAntiviral treatmentRevision diagnosisCommentary Article: Strategic Planning for Addiction Programs within Academic Medical Centers: Examples from the Yale Program in Addiction Medicine
Biegacki ET, Tetrault JM, Fiellin DA. Commentary Article: Strategic Planning for Addiction Programs within Academic Medical Centers: Examples from the Yale Program in Addiction Medicine. Substance Abuse 2022, 43: 1215-1220. PMID: 35657646, DOI: 10.1080/08897077.2022.2074606.Commentaries, Editorials and Letters
2021
SOAPs and SUDs: Patients With Substance Use Disorders and What Clinicians Should Know About the Cures Act
Chan CA, Tetrault JM, Fiellin DA, Weimer MB. SOAPs and SUDs: Patients With Substance Use Disorders and What Clinicians Should Know About the Cures Act. Journal Of Addiction Medicine 2021, 16: 141-142. PMID: 34049315, DOI: 10.1097/adm.0000000000000879.Commentaries, Editorials and Letters
2020
Patients With Opioid Use Disorder Deserve Trained Providers.
Weimer MB, Tetrault JM, Fiellin DA. Patients With Opioid Use Disorder Deserve Trained Providers. Annals Of Internal Medicine 2020, 172: 774-775. PMID: 32479150, DOI: 10.7326/l20-0084.Commentaries, Editorials and Letters
2019
Patients With Opioid Use Disorder Deserve Trained Providers.
Weimer MB, Tetrault JM, Fiellin DA. Patients With Opioid Use Disorder Deserve Trained Providers. Annals Of Internal Medicine 2019, 171: 931-932. PMID: 31766053, DOI: 10.7326/m19-2303.Commentaries, Editorials and Letters
2017
More Beds or More Chairs? Using a Science-Based Approach to Address the Opioid Epidemic.
Tetrault JM, Fiellin DA. More Beds or More Chairs? Using a Science-Based Approach to Address the Opioid Epidemic. Annals Of Internal Medicine 2017, 168: 73-74. PMID: 29159399, DOI: 10.7326/m17-2854.Commentaries, Editorials and Letters
2016
Primary Care Physicians’ Willingness to Prescribe HIV Pre-exposure Prophylaxis for People who Inject Drugs
Edelman EJ, Moore BA, Calabrese SK, Berkenblit G, Cunningham C, Patel V, Phillips K, Tetrault JM, Shah M, Fiellin DA, Blackstock O. Primary Care Physicians’ Willingness to Prescribe HIV Pre-exposure Prophylaxis for People who Inject Drugs. AIDS And Behavior 2016, 21: 1025-1033. PMID: 27896552, PMCID: PMC5344709, DOI: 10.1007/s10461-016-1612-6.Peer-Reviewed Original ResearchConceptsPrimary care physiciansPre-exposure prophylaxisCare physiciansHIV pre-exposure prophylaxisHIV risk groupMore HIVClinic patientsRisk groupsGeneral internistsPWIDAcademic general internistsPractice characteristicsDisease preventionHIVPrEPProphylaxisPatientsPhysiciansCareDrugsOnline surveyInternistsHigher willingnessLower willingnessCentral roleA Cross-Sectional Online Survey of HIV Pre-Exposure Prophylaxis Adoption Among Primary Care Physicians
Blackstock OJ, Moore BA, Berkenblit GV, Calabrese SK, Cunningham CO, Fiellin DA, Patel VV, Phillips KA, Tetrault JM, Shah M, Edelman EJ. A Cross-Sectional Online Survey of HIV Pre-Exposure Prophylaxis Adoption Among Primary Care Physicians. Journal Of General Internal Medicine 2016, 32: 62-70. PMID: 27778215, PMCID: PMC5215171, DOI: 10.1007/s11606-016-3903-z.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHealth PersonnelHealth Risk BehaviorsHIV InfectionsHumansMaleMiddle AgedMultivariate AnalysisOdds RatioPractice Patterns, Physicians'Pre-Exposure ProphylaxisPrimary Health CareSurveys and QuestionnairesConceptsPrimary care physiciansHIV care experienceCare physiciansPrEP adoptionPrEP awarenessPractice characteristicsHIV pre-exposure prophylaxisCare experiencesAcademic primary care physiciansHIV-positive patientsPre-exposure prophylaxisHealth care providersResultsThe survey response rateSectional Online SurveyPCP adoptionHIV careKey ResultsThe survey response ratePercent of respondentsRisk compensationSurvey response ratePrEP knowledgePrEP useSelf-rated knowledgeMultivariable analysisClinical championsHepatic Safety of Buprenorphine in HIV-Infected and Uninfected Patients With Opioid Use Disorder: The Role of HCV-Infection
Tetrault JM, Tate JP, Edelman EJ, Gordon AJ, Re V, Lim JK, Rimland D, Goulet J, Crystal S, Gaither JR, Gibert CL, Rodriguez-Barradas MC, Fiellin LE, Bryant K, Justice AC, Fiellin DA. Hepatic Safety of Buprenorphine in HIV-Infected and Uninfected Patients With Opioid Use Disorder: The Role of HCV-Infection. Journal Of Substance Use And Addiction Treatment 2016, 68: 62-67. PMID: 27431048, PMCID: PMC4976086, DOI: 10.1016/j.jsat.2016.06.002.Peer-Reviewed Original ResearchConceptsLiver enzyme elevationAlcohol use disorderUninfected patientsHepatotoxic medicationsHCV infectionUse disordersComposite endpointLiver injuryHIV/HCV co-infected patientsHCV co-infected patientsHIV/HCV statusPre-existing liver injuryCo-infected patientsCohort of HIVHepatitis C infectionHIV/HCVOpioid use disorderRisk of hepatotoxicityHCV statusHepatic safetyMedian ALTC infectionChart reviewEnzyme elevationHIV infection
2014
The Impact of Recent Cocaine Use on Plasma Levels of Methadone and Buprenorphine in Patients with and Without HIV-infection
Tetrault JM, McCance-Katz EF, Moody DE, Fiellin DA, Lruie BS, DInh AT, Fiellin LE. The Impact of Recent Cocaine Use on Plasma Levels of Methadone and Buprenorphine in Patients with and Without HIV-infection. Journal Of Substance Use And Addiction Treatment 2014, 51: 70-74. PMID: 25480096, DOI: 10.1016/j.jsat.2014.10.010.Peer-Reviewed Original ResearchConceptsRecent cocaine useHIV infectionCocaine useNorbuprenorphine concentrationsHIV statusBuprenorphine concentrationsS-methadoneAntiretroviral medication useBuprenorphine plasma concentrationsUninfected subjectsMethadone concentrationsMedication usePlasma levelsPlasma concentrationsR-methadoneCocaine effectsClinical careMethadoneBuprenorphineHIVInfectionAbstinenceSubjectsCocaineStatusSubstance use in older HIV-infected patients
Edelman EJ, Tetrault JM, Fiellin DA. Substance use in older HIV-infected patients. Current Opinion In HIV And AIDS 2014, 9: 317-324. PMID: 24824888, PMCID: PMC4175926, DOI: 10.1097/coh.0000000000000069.Peer-Reviewed Original ResearchConceptsOpioid use disorderUse disordersSubstance useTreatment optionsHealth consequencesPotential treatment optionStimulant use disorderRelated health consequencesOlder HIVAntiretroviral therapyHIVPatientsBrief counselingHealth outcomesEffective interventionsComplex needsMedicationsDisordersCounseling strategiesInterventionOutcomesTobaccoLife courseOptionsTherapy
2013
Racial/ethnic differences in report of drug testing practices at the workplace level in the U.S.
Becker WC, Meghani S, Tetrault JM, Fiellin DA. Racial/ethnic differences in report of drug testing practices at the workplace level in the U.S. American Journal On Addictions 2013, 23: 357-362. PMID: 24112118, DOI: 10.1111/j.1521-0391.2013.12109.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsBlack or African AmericanCross-Sectional StudiesData CollectionEducational StatusEmploymentFemaleHispanic or LatinoHumansIncomeMaleMiddle AgedMultivariate AnalysisOccupationsPrejudiceResidence CharacteristicsSelf ReportSex FactorsSubstance Abuse DetectionWhite PeopleWorkplaceYoung AdultConceptsDrug testingBlack raceStratified analysisWorkplace drug testingEthnic differencesSubstance abuse/dependenceImportant public health implicationsNon-urban residenceCross-sectional studyLogistic regression analysisAbuse/dependencePublic health implicationsDrug testing practicesSupport occupationsRace/ethnicityMale sexMultivariable analysisHispanic ethnicityDrug useYounger ageDrug testing policiesHealth implicationsFurther studiesHispanic respondentsRegression analysisAssociation Between Risk Behaviors and Antiretroviral Resistance in HIV-Infected Patients Receiving Opioid Agonist Treatment
Tetrault JM, Kozal MJ, Chiarella J, Sullivan LE, Dinh AT, Fiellin DA. Association Between Risk Behaviors and Antiretroviral Resistance in HIV-Infected Patients Receiving Opioid Agonist Treatment. Journal Of Addiction Medicine 2013, 7: 102-107. PMID: 23388678, PMCID: PMC3618545, DOI: 10.1097/adm.0b013e31827f9bdf.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentTransmission risk behaviorsHIV transmission risk behaviorsInjection drug useAgonist treatmentARV resistanceRisk behaviorsDrug useAntiretroviral resistanceUrine toxicologyClass resistanceSelf-reported HIV risk behaviorsTriple-class resistanceOpioid treatment programsPositive urine toxicologyOpioid-dependent individualsPercent of subjectsHIV risk behaviorsCross-sectional studyResource limited settingsIllicit drug useHIV seroconversionRisky sexual behaviorHIV resistanceResistant viruses
2012
Physician Detection of Unhealthy Substance Use on Inpatient Teaching and Hospitalist Medical Services
Holt SR, Ramos J, Harma M, Cabrera F, Louis-Ashby C, Dinh A, Fiellin DA, Tetrault JM. Physician Detection of Unhealthy Substance Use on Inpatient Teaching and Hospitalist Medical Services. The American Journal Of Drug And Alcohol Abuse 2012, 39: 121-129. PMID: 22992028, DOI: 10.3109/00952990.2012.715703.Peer-Reviewed Original ResearchConceptsUnhealthy substance useAlcohol Use Disorders Identification Test-ConsumptionDrug Abuse Screening TestHospitalist serviceSubstance useScreening testSubstance Involvement Screening TestPhysicians' detection ratesUnhealthy drug useMedical record reviewTeaching serviceCommunity teaching hospitalMedical servicesCross-sectional studyICD-9 codingRate of detectionAbuse Screening TestEligible patientsMedicine admissionsCurrent smokersRecord reviewDetection ratePhysician detectionTeaching hospitalPhysician documentationBrief versus extended counseling along with buprenorphine/naloxone for HIV-infected opioid dependent patients
Tetrault JM, Moore BA, Barry DT, O'Connor PG, Schottenfeld R, Fiellin DA, Fiellin LE. Brief versus extended counseling along with buprenorphine/naloxone for HIV-infected opioid dependent patients. Journal Of Substance Use And Addiction Treatment 2012, 43: 433-439. PMID: 22938914, DOI: 10.1016/j.jsat.2012.07.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineBuprenorphine, Naloxone Drug CombinationCounselingDelivery of Health Care, IntegratedFeasibility StudiesFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsOpioid-Related DisordersPsychotherapy, BriefSubstance Abuse DetectionTime FactorsTreatment OutcomeViral LoadConceptsEnhanced medical managementPhysician managementDetectable HIV viral loadHIV treatment settingsOpioid-negative urinesBuprenorphine/naloxoneHIV viral loadOpioid-dependent patientsPercentage of subjectsUntreated opioid dependenceExtended counselingHIV clinicHIV outcomesBuprenorphine/Medical managementOpioid dependenceViral loadDependent patientsExtensive counselingClinical trialsContinuous abstinenceNegative urineTreatment settingsGroup differencesCounselingPrevious Use of Alcohol, Cigarettes, and Marijuana and Subsequent Abuse of Prescription Opioids in Young Adults
Fiellin LE, Tetrault JM, Becker WC, Fiellin DA, Hoff RA. Previous Use of Alcohol, Cigarettes, and Marijuana and Subsequent Abuse of Prescription Opioids in Young Adults. Journal Of Adolescent Health 2012, 52: 158-163. PMID: 23332479, PMCID: PMC3552239, DOI: 10.1016/j.jadohealth.2012.06.010.Peer-Reviewed Original ResearchConceptsPrescription opioidsPrevious marijuana usePrevious substance usePrevious alcoholMarijuana useSubsequent abuseYoung womenSubstance useYoung adulthoodCommunity-dwelling individualsLogistic regression analysisCurrent abusePrevious alcohol useClinical dataOpioidsDrug useSubstance abuseAlcohol useCigarettesPrevention effortsPrevious useYoung adultsYoung individualsYoung menYear oldsCombining Rapid HIV Testing and a Brief Alcohol Intervention in Young Unhealthy Drinkers in the Emergency Department: A Pilot Study
Edelman EJ, Dinh A, Radulescu R, Lurie B, D'Onofrio G, Tetrault JM, Fiellin DA, Fiellin LE. Combining Rapid HIV Testing and a Brief Alcohol Intervention in Young Unhealthy Drinkers in the Emergency Department: A Pilot Study. The American Journal Of Drug And Alcohol Abuse 2012, 38: 539-543. PMID: 22794939, PMCID: PMC3522092, DOI: 10.3109/00952990.2012.701359.Peer-Reviewed Original ResearchConceptsSexual risk reduction counselingSexual risk behaviorsRisk reduction counselingRapid HIV testingEmergency departmentRisk behaviorsReduction counselingHIV testingAlcohol useUnhealthy drinkersAlcohol consumptionMean age 26 yearsAverage weekly drinksImportant preventive servicesAlcohol Use Disorders Identification Test (AUDIT) scoresUnknown HIV statusRapid HIV testsUnhealthy alcohol useAge 26 yearsBrief alcohol interventionHIV testHIV statusRegular doctorPreventive servicesRisk populationsScreening, Brief Intervention, and Referral to Treatment (SBIRT) for Alcohol and Other Drug Use among Adolescents: Evaluation of a Pediatric Residency Curriculum
Ryan SA, Martel S, Pantalon M, Martino S, Tetrault J, Thung SF, Bernstein SL, Auinger P, Green ML, Fiellin DA, O'Connor P, D'Onofrio G. Screening, Brief Intervention, and Referral to Treatment (SBIRT) for Alcohol and Other Drug Use among Adolescents: Evaluation of a Pediatric Residency Curriculum. Substance Abuse 2012, 33: 251-260. PMID: 22738002, DOI: 10.1080/08897077.2011.640182.Peer-Reviewed Original ResearchConceptsBrief Negotiation InterviewBrief interventionPediatric residency programsDrug useKnowledge scorePost-training improvementPost-training knowledge scoresMain outcome measuresUrban teaching hospitalAdolescent medicine rotationPediatric residency curriculumMedicine/pediatric residentsResidency programsTraining satisfactionAdherence ScaleSBIRT curriculumTeaching hospitalOutcome measuresSignificant preTreatment curriculumClinical practiceClinical settingPediatric residentsResidents' knowledgeResidency curriculum