Christine Jacobs-Wagner, PhD

William H. Fleming, M.D. Professor of Molecular, Cellular, and Developmental Biology and of Microbial Pathogenesis; HHMI Investigator; Director of Microbial Sciences Institute

Research Interests

Bacteria; Bacterial Processes; Biological Processes

Research Organizations

Microbial Pathogenesis

Faculty Research

Microbial Sciences Institute

Research Summary

We study the molecular mechanisms underlying bacterial multiplication. Bacteria are renowned for their fast multiplication. During their short cell cycles, bacteria grow, replicate and segregate their chromosomes and divide. They do all of this with sometimes blazing speed and with remarkable temporal and spatial accuracy, which explains their success.

Despite the medical, agricultural and ecological importance of bacteria, little is known about the molecular mechanisms involved in growth, DNA segregation, cell division and cell morphogenesis. Similarly, the temporal and spatial mechanisms regulating these essential processes remain largely elusive. We address these fundamental questions using genetics, biochemistry, quantitative fluorescence microscopy and modeling.

Selected Publications

Full List of PubMed Publications

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Contact Info

Christine Jacobs-Wagner, PhD
Mailing Address
ABC 317BPO BOX 27388
West Haven, CT 06516

Jacobs-Wagner Lab