M Bruce Shields, MD

Professor Emeritus of Ophthalmology and Visual Science; Chairman Emeritus

Research Organizations


Office of Cooperative Research

Research Summary

Over the past 25 years, my research has focused on glaucoma, with special emphasis of mechanisms of certain forms of glaucoma (e.g., the Axenfeld-Rieger syndrome and the iridocorneal endothelial syndrome), diagnostic measures (especially computerized image analysis of the optic nerve head), and therapeutic approaches (clinical drug trials and extensive evaluation of laser cyclo- photocoagulation for unusually difficult forms forms of glaucoma and surgical approaches to combined cataract and glaucoma).

I am currently investigating a glaucoma shunt device, called Aquashunt, for which we received US patent in 2006. A start up company, called Vidus Ocular, was started at Yale which conducted pre-clinical trials in 2007-2008. The company was purchased by OPKO Health in 2008, which supported clinical trials in 2009 with favorable outcome measures. Sale of the device to a larger company is currently under negotiation.

Selected Publications

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Contact Info

M Bruce Shields, MD
Patient Care Location
Yale Eye CenterTemple Medical Center
40 Temple Street, Ste 3rd floor

New Haven, CT 06510
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Office Location
Temple Medical Center
40 Temple Street, Ste 3rd Floor

New Haven, CT 06510
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Mailing Address
OphthalmologyYale School of Medicine
P.O. Box 208061

New Haven, CT 06520-8061