The main goal of the Cell Core is to facilitate the experimental use of authentic primary isolated mouse and rat osteoblastic cells as well as primary osteoclasts and osteoclast-like cells generated from co-culture.
- Isolation and cultivation of primary murine and fetal rat calvarial osteoblasts. This includes large scale preparations for biochemical studies and RNA and DNA purification.
- Cultivation of murine osteoclast-like cells generated from in vitro co-culture.
- Isolation of authentic osteoclasts from rabbits and rats.
- Training in the in vitro isolation and culture of osteoblastic and osteoclastic cells, so that investigators, appropriately trained, can initiate and maintain these cells in their laboratories.