Skip to Main Content
VA Family of EHR Cohorts (VACo Family)
YSM Home

INFORMATION FOR

STEP Trials

Overview

The Starting Treatment for Ethanol in Primary HIV Care (STEP) Trials were three linked randomized clinical trials designed to evaluate the impact of integrated stepped alcohol treatment to address unhealthy alcohol use among individuals with HIV.

The STEP Trials were sponsored by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), Grant # 5 U01 AA020795-10 (NIH Reporter Abstract).

Questions or requests for further information regarding the STEP Trials should be directed to Beth Porter.

Training Scenarios

Brief Negotiated Interview and Personal Feedback Reports

Motivational Enhancement Therapy and Personal Feedback Reports

Case 1: JB

Case 2: SD

Publications

  • Edelman EJ, Hansen NB, Cutter CJ, Danton C, Fiellin LE, O'Connor PG, Williams EC, Maisto SA, Bryant KJ, Fiellin DA. Implementation of integrated stepped care for unhealthy alcohol use in HIV clinics. Addict Sci Clin Pract. 2016 Jan 13;11(1):1. doi: 10.1186/s13722-015-0048-z. PubMed ID: 26763048
  • Edelman EJ, Maisto SA, Hansen NB, Cutter CJ, Dziura J, Fiellin LE, O'Connor PG, Bedimo R, Gibert C, Marconi VC, Rimland D, Rodriguez-Barradas MC, Simberkoff MS, Justice AC, Bryant KJ, Fiellin DA. The Starting Treatment for Ethanol in Primary care Trials (STEP Trials): Protocol for Three Parallel Multi-Site Stepped Care Effectiveness Studies for Unhealthy Alcohol Use in HIV-Positive Patients. Contemp Clin Trials. 2017 Jan;52:80-90. doi: 10.1016/j.cct.2016.11.008. Epub 2016 Nov 20. Erratum in: Contemp Clin Trials. 2017 Sep;60:125. PubMed ID: 27876616
  • Edelman EJ, Maisto SA, Hansen NB, Cutter CJ, Dziura J, Deng Y, Fiellin LE, O'Connor PG, Bedimo R, Gibert CL, Marconi VC, Rimland D, Rodriguez-Barradas MC, Simberkoff MS, Tate JP, Justice AC, Bryant KJ, Fiellin DA. Integrated stepped alcohol treatment for patients with HIV and liver disease: A randomized trial. J Subst Abuse Treat. 2019 Nov;106:97-106. doi: 10.1016/j.jsat.2019.08.007. Epub 2019 Aug 17. PubMed ID: 31540617
  • Edelman EJ, Maisto SA, Hansen NB, Cutter CJ, Dziura J, Deng Y, Fiellin LE, O'Connor PG, Bedimo R, Gibert CL, Marconi VC, Rimland D, Rodriguez-Barradas MC, Simberkoff MS, Tate JP, Justice AC, Bryant KJ, Fiellin DA. Integrated stepped alcohol treatment for patients with HIV and alcohol use disorder: a randomised controlled trial. Lancet HIV. 2019 Aug;6(8):e509-e517. doi: 10.1016/S2352-3018(19)30076-1. Epub 2019 May 17. PubMed ID: 31109915
  • Edelman EJ, Maisto SA, Hansen NB, Cutter CJ, Dziura J, Deng Y, Fiellin LE, O'Connor PG, Bedimo R, Gibert CL, Marconi VC, Rimland D, Rodriguez-Barradas MC, Simberkoff MS, Tate JP, Justice AC, Bryant KJ, Fiellin DA. Integrated stepped alcohol treatment for patients with HIV and at-risk alcohol use: a randomized trial. Addict Sci Clin Pract. 2020 Jul 29;15(1):28. doi: 10.1186/s13722-020-00200-y. PubMed ID: 32727618
  • Eyawo O, Deng YH, Dziura J, Justice AC, McGinnis K, Tate JP, Rodriguez-Barradas MC, Hansen NB, Maisto SA, Marconi VC, O'Connor PG, Bryant K, Fiellin DA, Edelman EJ. Validating self-reported unhealthy alcohol use with phosphatidylethanol (PEth) among patients with HIV. Alcoholism: Clinical and Experimental Research. 2020 Oct; 44(10):2053-2063. doi:10.1111/acer.14435.

STEP Trial Documents

Document Description
Addiction Physician Management - Initial Visit Structured encounter form to guide first Addiction Physician Management visit
Addiction Physician Management - Biweekly/Monthly Visit Structured encounter form to guide folllow-up Addiction Physician Management visits
Behavior Skills for Alcohol Reduction Workbook Workbook psychologists may provide patients during motivational enhancement therapy
Brief Negotiated Interview Manual Brief Negotiated Interview training manual for Social Workers
Brief Negotiated Interview Encounter Form Structured encounter form to guide Brief Negotiated Interview initial visit
Brief Negotiated Interview Booster Encounter Form Structured encounter form to guide Brief Negotiated Interview booster telephone call
Clinician Feedback Form Guide To guide to understanding and interpretation of Patient Feedback Form
Drinking Agreement For Social Workers to complete with participant during initial BNI viist
Motivational Enhancement Therapy Manual Motivational Enhancement Training manual for Psychologists (or other qualified clinician)
Motivational Enhancement Therapy Initial Therapist Encounter Form Structured encounter form to guide first Motivational Enhancement Therapy (MET) visit
Motivational Enhancement Therapy Encounter Form Structured encounter form to guide follow-up Motivational Enhancement Therapy (MET) visits
Motivational Interviewing Overview Motivational Interviewing training guide as useful skills for all clinicians
MRAC Standard Drink Converter 2003 For quantifying alcohol consumption
STEP Trial Feedback Form Tailored feedback for patient regarding alcohol use and its potential impact on individual's health, based on patient-reported assessments and labs
STEP Trial Personal Feedback Report Brochures STEP Trial Feedback Form guide for patients

Patient-Facing Materials