Yale Lupus Program

Systemic Lupus Erythematosus (SLE, or lupus) is autoimmune disease in which the immune system causes inflammation in the joints, skin, kidneys, lungs, and other internal organs. Rheumatologists are experts in the care and treatment of patients with lupus, and at the Yale Lupus Program, they also coordinate care with other specialists to provide comprehensive evaluation and treatment plans. Yale School of Medicine lupus researchers are also part of the Program, with the goal to advance the treatment and understanding of this complex disease. The Program thus provides unparalleled access to experts in the clinical care and treatment of patients with SLE, and the most up-to-date information about new therapies.

The clinical program is directed by Fotios Koumpouras, MD, who also is the principle investigator of the Yale Rheumatology Biorepository.  The program offers the ability to follow patients with lupus over time using disease activity research tools (instruments). 

Clinical Care

With sites on Yale St. Raphael’s Campus and the YNHH Interventional Immunology Center at North Haven, the Yale Lupus Program provides comprehensive evaluation and treatment of patients, and education about the disease for patients and their family members. Patients are evaluated and treated by rheumatologists and other specialists, including dermatologists and nephrologists. The Program provides multidisciplinary evaluations by experts in maternal-fetal medicine, neurology, pulmonary medicine, and cardiology. The Program also contains:

  • A state-of-the art Infusion Center for administration of the most up-to-date therapies.
  • A Lupus Wellness Program: Lupus can be a complicated condition to understand and education is the first step in empowering people to be an active part of their treatment decisions and improve the quality of their life.
  • A Transition Program for young adults with lupus that works towards each person’s individual goals emphasizing education and shared decision making.

Referrals to the program can be made through EPIC or by faxing patient information and the new patient referral form to 203-785-7053.


An essential part of the Yale Lupus Program is ongoing clinical and translational research, with the goal of reaching a better understanding the cause of lupus, and advancing treatment. Patients at the Program have access to novel therapies and the opportunity to participate in clinical research studies should they choose to do so.

Lupus Wellness Program

The Yale Lupus Program offers a comprehensive Lupus Wellness Program that provides lupus patients with knowledge about their disease, and methods and means to manage multiple aspects of their health. Meeting in a one on one session with the nurse practitioner, patients learn about how their disease affects their bodies and how to recognize and manage lupus symptoms. Lupus patients are also taught how to incorporate preventative health practices into their day to day lives, and improve self-advocacy and adherence. The Lupus Wellness Program empowers patients with tools to help maximize communication with their health care providers and use technology to maintain their own personal health records. The program also hosts support group meetings throughout the year where participants can not only meet other people with lupus, but also learn about nutrition, exercise, and stress reduction techniques together. The Lupus Wellness Program is an especially important resource for those newly diagnosed with lupus or those who are transitioning from pediatric rheumatology practice into the adult rheumatology setting. The program is also offered in Spanish.

To learn more or to make an appointment with Jacinta Renaldi RNP