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Daniel Chamié, MD, PhD

Instructor of Medicine (Cardiovascular Medicine)

Contact Information

Daniel Chamié, MD, PhD

Mailing Address

  • Yale School of Medicine

    135 College Street

    New Haven, Connecticut 06510

    United States

Appointments

Biography

Daniel Chamié is an Interventional Cardiologist with expertise in complex percutaneous coronary interventions (PCI), intravascular imaging modalities, and coronary physiology.

He received his M.D. degree in 2001 and completed his Internal Medicine and Cardiology residencies in Rio de Janeiro, Brazil, before moving to Sao Paulo, Brazil, where he completed the Hemodynamics and Interventional Cardiology training at Instituto Dante Pazzanese de Cardiologia, from 2006 and 2009. Between 2010 and 2012 he completed a 2-year research fellowship in Intravascular Imaging at the University Hospitals Case Medical Center, Case Western Reserve University in Cleveland, OH, where he advanced his knowledge in the use of intracoronary physiology and imaging, particularly optical coherence tomography (OCT).

Upon completing his research fellowship in Cleveland, Dr. Chamié returned to Brazil and served as faculty of the Interventional Cardiology Department at Instituto Dante Pazzanese de Cardiologia in Sao Paulo, where he practiced for 10 years expanding his skills in complex percutaneous coronary interventions and in the clinical use of intravascular imaging and physiology.

In 2019, he obtained his Ph.D. in Medicine, Technology, and Interventions in Cardiology from the University of Sao Paulo.

In parallel with his clinical activities, Dr. Chamié directed the OCT core laboratory at the Cardiovascular Research Center, Sao Paulo, Brazil, from 2012 to 2020. During this time, he developed OCT analysis methods for several studies on novel devices (e.g. bioresorbable scaffolds, drug-eluting stents, specialty balloons) in various clinical scenarios (e.g. stable CAD, ACS, bifurcation lesions, high-bleeding risk patients, etc).

Over the last decade, he participated as an investigator for several clinical trials, first-in-man studies, registries, and observational studies. Dr. Chamié is the leading investigator of the iSIGHT trial and the VIP-LMS study. The former proposes an algorithmic approach for the use of intravascular imaging to guide PCI; the latter aims to validate the use of intracoronary physiology (iFR and FFR) and imaging (IVUS and OCT) in patients with intermediate left main coronary artery stenosis with concomitant severe downstream lesions.

In August 2022, Dr. Chamié moved to the US to join the Section of Cardiovascular Medicine at Yale School of Medicine in New Haven, CT as an Instructor. Over this period, he established intravascular ultrasound, optical coherence tomography, and coronary physiology core laboratories and is working in close collaboration with the cardiac catheterization laboratory team at Yale New Haven Health to advance the use of intravascular imaging modalities in clinical practice.

Dr. Chamié is a Commissioner for the Lancet Commission for Ischemic Heart Disease, working with a group of leaders in the field to produce a forward-looking document that aims to advocate for increased awareness of the impact of atherosclerotic cardiovascular disease, to impact on health policy interventions targeted at prevention, early detection, and treatment of atherosclerotic heart disease globally, and to propose an agenda for atherosclerotic heart disease research for the next 20 years.

Dr. Chamié serves as an associate editor for the Journal of Transcatheter Interventions since 2018 and is a member of the editorial board of the JSCAI: Journal of the Society for Cardiovascular Angiography and Interventions since 2022. He is also a reviewer for high-impact peer-reviewed journals in the area of Cardiology and Cardiovascular interventions (e.g. JACC, JACC Cardiovascular Interventions, Circulation: Cardiovascular Interventions, EuroIntervention, Cardiovascular Revascularization Medicine, and JSCAI) and is regularly invited to speak at leading international conferences.

Education & Training

  • PhD
    University of Sao Paulo, Medicine, Technology and Interventions in Cardiology (2019)
  • Fellowship
    University Hospitals Case Medical Center, Case Western Reserve University (2012)
  • Fellowship
    Instituto Dante Pazzanese de Cardiologia (2009)
  • Residency
    Instituto Estadual de Cardiologia Aloysio de Castro (2005)
  • Residency
    Hospital Municipal Lourenco Jorge (2003)
  • MD
    Fundacao Educacional Serra dos Orgaos, Medical School (2001)

Activities

  • SMART Trial and PREVENT Trial
    Webinar organized by the Brazilian Society of Hemodynamics and Cardiovascular Interventions. The webinar contained summary presentations and expert discussions of the SMART and PREVENT trials that were recently presented at the ACC 2024. 2024
    Webinar SBHCI
  • Plaque Characterization in Coronary Artery Disease Using Computed Tomography Angiography - Cardiac CT Special Issue
    This SCAI Interview hosted a group of leaders to discuss the new Cardiac CT Special Issue published by JSCAI. The session was moderated by Dr. Jonathon A. Leipsic (Vancouver, Canada) and Daniel Chamié (Yale School of Medicine), and featured presentations by Drs. Bon-Kwon Koo (Seoul National University Hospital, Seoul, Korea), Sarah Rinehart (Charleston Area Medical Center, Charleston, West Virginia), and Christos Bourantas (Barts Heart Centre, London, UK). 2024
    SCAI Video Interview
  • Management of Calcified Coronary Lesions - SCAI Document
    SCAI Webinar with a panel of experts comprised of Daniel Chamié, Alexandra Lansky, Robert Riley, and Binita Shah to discuss the new SCAI document on the management of calcified coronary lesions 2024
    SCAI Video Interview
  • Integrating intravascular imaging into modern-day PCI
    New Haven, CT, United States 2023
    12th Annual Interventional Cardiology Symposium
  • Coronary Spotlight 15: Physiology and Imaging: Emerging Techniques, Technologies and Trials - Physiology and Imaging: Emerging Techniques, Technologies and Trials
    San Francisco, CA, United States 2023
    Transcatheter Cardiovascular Therapeutics (TCT)
  • Drug-Eluting Stent to Allow Adaptive Remodeling
    San Francisco, CA, United States 2023
    Transcatheter Cardiovascular Therapeutics (TCT)
  • How I Use Intravascular Imaging to Guide PCI for Left Main
    San Francisco, CA, United States 2023
    Transcatheter Cardiovascular Therapeutics (TCT)
  • AI Applications in Intracoronary Imaging and Invasive Physiology
    This was a meeting organized by SCAI and the Gulf Intervention Society on Artificial Intelligence in Interventional Cardiology & Revolution in Healthcare: AI in Coronary Artery Disease. This session was moderated by Drs. Ryan Madder and Bimmer Claessen, and hosted presentations from Drs. Daniel Chamié, Carlos Collet, and Hector Garcia-Garcia 2023
    SCAI & Gulf Intervention Society Summit: Artificial Intelligence in Interventional Cardiology & Revolution in Healthcare
  • Case #8: Under-Expanded Stent with ISR Treated by Laser, Atherectomy, or Lithotripsy
    San Diego, CA, United States 2023
    Transcatheter Cardiovascular Therapeutics (TCT)
  • Case #9: Very Late Stent Thrombosis
    San Diego, CA, United States 2023
    Transcatheter Cardiovascular Therapeutics (TCT)
  • Edited Cases
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • Live Case from China
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • When and How to Combine Imaging and Physiology?
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • Live Case from Germany
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • Angiography-derivded FFR: Rationale and Principles of uFR
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • Live Case - INC
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • Beyond coronariography: Diagnostic methods in Non-Obstructive ischemic disease
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • Mastering Intravascular Ultrasound
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • Best Abstract Competition
    Rio de Janeiro, RJ, Brazil 2023
    SOLACI
  • Is X-Ray Enough? Angio & CT-Based Physiology
    New York, NY, United States 2023
    Optimizing PCI Conference
  • Angiography-Derived Physiology and Co-Registration
    New Haven, CT, United States 2022
    11th Annual Interventional Cardiology Symposium - Physiology Guided Diagnosis and Intervention: Precision Medicine in the Catheterization Laboratory
  • Intracoronary Imaging
    The conferences are aimed to teach topics in interventional cardiology to fellows and faculty. 2022
    Yale Cath Conference
  • Imaging and Physiology to Treat Calcified Lesions
    Boston, MA, United States 2022
    Transcatheter Cardiovascular Therapeutics 2022
  • Fractional Flow Reserve vs. Non Hyperemic Pressure Ratio
    Belo Horizonte, MG, Brazil 2022
    SBHCI Congress 2022
  • Can OCT Replace IVUS in All Scenarios?
    Belo Horizonte, MG, Brazil 2022
    SBHCI Congress 2022
  • How to Interpret Hyperemic and Non-Hyperemic Physiologic Indices Beyond the "Magic Number"?
    Belo Horizonte, MG, Brazil 2022
    SBHCI Congress 2022
  • Precision PCI: Should We Integrate Imaging and Physiology?
    Belo Horizonte, MG, Brazil 2022
    SBHCI Congress 2022
  • New PressureWire Omniwire. Just an update or a revolution?
    Belo Horizonte, MG, Brazil 2022
    Philips Symposium - SBHCI Congress 2022
  • Practical Application of the Refinity IVUS Catheter in One Case
    Belo Horizonte, MG, Brazil 2022
    Philips Symposium - SBHCI Congress 2022
  • Practical Application of SyncVision in One Case
    Belo Horizonte, MG, Brazil 2022
    Philips Symposium - SBHCI Congress 2022
  • Late Scaffold Failure Due to Intraluminal Scaffold Dismantling
    Denver, CO, United States 2017
    Transcatheter Cardiovascular Therapeutics (TCT)
  • Mechanisms and Predictors of BRS Restenosis
    Denver, CO, United States 2017
    Transcatheter Cardiovascular Therapeutics (TCT)
  • BRS Embolization and Geographic Miss
    Denver, CO, United States 2017
    Transcatheter Cardiovascular Therapeutics (TCT)
  • How to Use Imaging During Bioresorbable Scaffold Implantation
    Denver, CO, United States 2017
    Transcatheter Cardiovascular Therapeutics (TCT)
  • Step-By-Step Assessment of Physiologic Lesion Significance
    Denver, CO, United States 2017
    Transcatheter Cardiovascular Therapeutics (TCT)
  • Step-By-Step Endovascular Imaging Interpretation (IVUS and OCT Case-based Review)
    Denver, CO, United States 2017
    Transcatheter Cardiovascular Therapeutics (TCT)
  • Live Case
    San Francisco, CA, United States 2015
    Transcatheter Cardiovascular Therapeutics (TCT)
  • MIRAGE Bioresorbable Scaffold Implantation
    Washington, DC, United States 2014
    Transcatheter Cardiovascular Therapeutics (TCT)
  • Optical Coherence Tomography: Future Perspectives
    São Paulo, SP, Brazil 2013
    SOLACI in Partnership with TCT
  • Incidence, Predictors, Morphological Characteristics, and Clinical Outcomes of Stent Edge Dissections Detected by OCT
    São Paulo, SP, Brazil 2013
    SOLACI in Partnership with TCT
  • First-In-Human Evaluation of the Novel DESolve Bioresorbable Scaffold
    São Paulo, SP, Brazil 2013
    SOLACI in Partnership with TCT
  • Evaluation of Neointimal Healing of EPC-Capturing Sirolimus-Eluting COMBO Stent by Optical Coherence Tomography: The EGO-COMBO Pilot Study (interim results)
    Miami, FL, United States 2012
    Transcatheter Cardiovascular Therapeutics

Honors & Recognition

AwardAwarding OrganizationDate
Best Oral Abstract: Optical coherence tomography versus intravascular ultrasound and angiography to guide percutaneous coronary interventions: the iSIGHT randomized trial.Sao Paulo Society of Cardiology (SOCESP)2019
Selected among the top five winners of the Senior Investigation AwardBrazilian Society of Cardiology2015
Young Leader AwardCardiovascular Research Technologies (CRT) Meeting2015
Young Investigator Award (second place)Brazilian Society of Cardiology2014
Top Five Best Abstracts: Incidence, predictors, morphological characteristics, and clinical outcomes of stent edge dissections detected by optical coherence tomographyLatin American Society of Interventional Cardiology (SOLACI)2013
Top Five Best Abstracts: Evaluation of the novel novolimus-eluting bioresorbable vascular scaffold for treatment of de novo coronary artery stenosis: serial optical coherence tomography analysis of the DESolve NX studyLatin American Society of Interventional Cardiology (SOLACI)2013
Translational Research Award (second place)Sao Paulo Society of Cardiology (SOCESP) Congress2013

Professional Service

OrganizationRoleDate
Journal of the American Heart AssociationReviewer2023 - Present
JSCAI: Journal of the Society for Cardiovascular Angiography and InterventionsEditorial Board Member2022 - Present
The Lancet Commission on Atherosclerotic Coronary Artery DiseaseA Lancet Commission is a prestigious, forward-looking, comprehensive assessment of the research priorities in major disease areas for the next 10-15 years, published in the leading medical journal The Lancet. The purpose of the current commission is to encourage the scientific community and medical societies to generate the evidence required to reduce the burden of atherosclerotic heart disease (coronary artery disease). The commission will highlight initiatives for regional and global research that inform and improve public health and healthcare for the world’s leading cause of death. This commission is produced by 22 diverse commissioners from around the world, selected for their expertise in relevant scientific and clinical fields. The relationships established among the commissioners often translate into enduring collaborative links that lead to important international research through clinical trials and subsequent publications. The commission will be a stimulus for research collaboration amongst all the commissioners over the next 15-20 years.2022 - Present
Circulation: Cardiovascular ImagingReviewer2022 - Present
JACC: Cardiovascular InterventionsReviewer2021 - Present
Circulation: Cardiovascular InterventionsReviewer2020 - Present
Arquivos Brasileiros de CardiologiaReviewer2020 - Present
JACC: Cardiovascular ImagingReviewer2019 - Present
Catheterization and Cardiovascular InterventionsReviewer2019 - Present
EuroInterventionReviewer2019 - Present
JACC Cardiovascular InterventionsReviewer2019 - Present
Arteriosclerosis, Thrombosis, and Vascular BiologyReviewer2019 - Present
Journal of Transcatheter InterventionsAssociate Editor2018 - Present
Cardiovascular Revascularization MedicineReviewer2018 - Present
Journal of Transcatheter InterventionsReviewer2018 - Present
International Journal of Cardiovascular ImagingReviewer2017 - Present

Departments & Organizations