Yale Physicians Reflect on Covid, Three Years Later
It’s been more than three years since the COVID pandemic began, causing over six million deaths worldwide (as of April 2023). While things have largely returned to normal thanks to vaccines, lockdowns, and public health measures and with the Public Health Emergency recently ending, life is a “new normal.” No one who has come out on the other side of the height of the pandemic has remained unaffected, whether physically, emotionally, or both. This is particularly true for the frontline healthcare workers who cared for very sick patients despite the fear of becoming ill themselves.
Study Uncovers Reduced Exercise Tolerance and Other Changes in Long COVID
A recent study published in Pulmonary Circulation assesses changes in oxygen extraction following post-acute sequelae of SARS-Cov-2 infection (PASC) syndrome, or “long COVID.” PASC may affect half of patients who recover from COVID-19. One debilitating hallmark is a persistent decrease in exercise tolerance.
The science behind why COVID-19 is killing more men than women
Although women contract COVID-19 at a comparable rate as men, the latter is more likely to develop critical manifestations of the disease--irrespective of age or region. In fact, on balance, men are 60% more likely to succumb to COVID-19 than women.Source: Ladders
Yale Engage COVID 19 Inflammation & Genetics, Where Biology Meets Translation
On June 3, 2020, nearly 350 industry representatives and academics joined the inaugural Yale Engage webinar series, Facilitating Collaboration to Combat COVID-19. Opening remarks were made by Michael Crair, PhD, the conversation was moderated by Ruth Montgomery, PhD, and the highly informative panelists included Akiko Iwasaki, PhD, Ellen Foxman, MD, PhD, Naftali Kaminski, MD, Carrie Lucas, PhD, Andrew Wang, MD, PhD. If you were unable to attend, or if you missed a portion of the webinar, please find a link to the recording below, along with a PDF of the panelists’ presentations.
Sharing a Ventilator, Sparing a Life: Two Yale Groups Create Different Ways To Maximize Ventilator Capacity in a Crisis
At Yale, two teams have created different solutions to the problem of how to split ventilators between more than one patient. In a crisis, that could mean the difference between life and death.
Fellow Focus in Four: Morgan Goheen, MD, PhD, Infectious Diseases
Morgan Goheen, MD, PhD, clinical fellow in infectious diseases at Yale School of Medicine, discusses "coming of age" as a physician during the pandemic, the research she plans to conduct through the Centennial Travel Award in Basic Science Tropical Disease Research, and her reading habits.
FDA says new COVID-19 vaccines will protect against current strains
EG.5, nicknamed Eris after the Greek goddess of chaos who indirectly started the Trojan War, makes up approximately 20.6% of current infections, while FL 1.5.1 comprises 13.3%. Both are Omicron variants. “The two strains, EG.5 and XBB.1.5, are not identical, but they're pretty close,” said Scott Roberts, an infectious disease specialist for Yale Medicine. “My strong suspicion is that, given the genetic similarities, there will still be a good degree of protection from the booster."Source: Washington Examiner
Researchers Are Testing Paxlovid as a Treatment for Long COVID
Long COVID currently affects millions of people in the U.S. Symptoms can include brain fog, tremors, sleep disorders, and shortness of breath. The National Institutes of Health (NIH) and other academic medical centers recently launched clinical trials aimed at finding treatments for long COVID. Researchers think that there may be different causes of long COVID symptoms in different people, which is why they are conducting different clinical trials in many centers around the country.Source: Verywell Health