Clinical Trials
The Section of Pulmonary, Critical Care and Sleep Medicine (PCCSM) advances the research of pharmaceutical, biological and medical device products by developing collaborations between industry and academia. The Institute seeks to provide an efficient integration of academic expertise and industry clinical objectives. PCCSM offers its industry sponsors access to valuable scientific leadership, focused operational research functionality and analysis of high quality clinical trial data. As a leading provider of clinical trial services, PCCSM plays an important role in assessing new products that improve the quality of peoples’ lives.
Active Clinical Trials
- Interstitial Lung Disease Program ( ILD )
For more information, see the Interstitial Lung Disease Program ( ILD ).
- Adult Cystic Fibrosis Program (CF)
G551D Observational Study- Expanded to Additional Genotypes and Extended for Long Term Follow up (GOAL- e2)
Status: Active - Enrolling.
Read More...Prevalence of Antibodies to Selected Porcine Viruses in Patients With Cystic Fibrosis Receiving Porcine-derived Pancreatic Enzyme Replacement Therapy
Status: Active - Enrolling.
Read More...A Phase 3 Rollover Study of Lumacaftor in Combination With Ivacaftor in Subjects 12 Years and Older With Cystic Fibrosis
Status: Active - Enrollment complete.
Read More...Long-term Study in US Cystic Fibrosis Patients Receiving Digestive Enzyme Supplements to Assess Any Narrowing of the Large Intestine Causing Adverse Intestinal Symptoms (Fibrosing Colonopathy)
Status: Active - Enrolling.
Read More...OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis (OPTIMIZE)
Status: Waiting activation to start enrolling subjects.
Read More...- Center for Asthma and Airway Diseases (YCAAD)
For more information, see the Center for Asthma and Airway Diseases (YCAAD).
- Center for Sleep Medicine
- For more information, see the Center for Sleep Medicine.
- COPD Center
- Pending IRB approval.
- Medical Intensive Care Unit (MICU)
- The MIND-USA Study: Modifying the Impact of ICU-Associated Neurological
Status: Active - Enrolling.
Read More... - Pulmonary Vascular Disease Program (PVDP)
ASC01 - A Randomized, Double-Blind, Placebo-Controlled, Phase II Multicenter Trial of a Monoclonal Antibody to CD20 (Rituximab) for the Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)
COMPASS2 - Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)
Status: Active - Enrolling.
Read More...
Status: Active - Closed to Enrollment.
Read More...- Thoracic Interventional Program (TIP)
RENEW (PneumRx): Lung Volume Reduction Coil for Treatment in Patients With Emphysema (RENEW) Study.
Status: Active - Enrolling
Read More...ASPIRE (Aeris): Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE).
Status: Active - Enrolling
Read More...ASAP (CareFusion/Duke): Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter on the Incidence of Auto-Pleurodesis in Patients With Malignant Pleural Effusions.
Status: Active - Enrolling
Read More...- Thoracic Oncology Program (TOP)
- ADX-0001 (Allegro): Airway Epithelium Gene Expression in the Diagnosis of Lung Cancer.
Status: Active - Closed to Enrollment
Read More... - Veteran's Administration - Pulmonary, Critical Care and Sleep Medicine
- Pending IRB approval.