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"Serendipity!" Meir Kryger (05/25/2022)

June 03, 2022

"Serendipity!" Meir Kryger (05/25/2022)

 .
  • 00:00Tell me what worked, what didn't work,
  • 00:02what I needed to improve,
  • 00:03and that was fantastic.
  • 00:05He taught me the mechanics of
  • 00:07clinical research and he encouraged
  • 00:10me to pursue sleep studies to
  • 00:13actually do stuff with sleep well.
  • 00:18Well, when you have lemons,
  • 00:20you make lemonade.
  • 00:21So here I was in in in Colorado,
  • 00:24my boss John Wilde tells me to
  • 00:27go and do sleep research and and
  • 00:30there there was no device that
  • 00:33was available for acquiring data.
  • 00:35There was nothing out there that could help.
  • 00:39And So what I got interested in
  • 00:41was sleep at high altitude and
  • 00:43this is the city of Leadville, Co.
  • 00:46The highest.
  • 00:47Human habitation in North America.
  • 00:50And there was a mine there,
  • 00:51so there was an actual town,
  • 00:54so I decided to do some some research
  • 00:58in this town and three things aligned.
  • 01:02And this again is serendipity.
  • 01:04So the three things that were
  • 01:07that aligned was I.
  • 01:09I wrote a letter to Helen Grass,
  • 01:12who was she and her husband
  • 01:14were the owners of the grass
  • 01:17company that made a polygraphs.
  • 01:20And I asked for a polygraph
  • 01:21and she sent me one.
  • 01:23And so that's that was one
  • 01:26thing that was important.
  • 01:28Hewlett Packard that year introduced
  • 01:31the fiber optic era oximeter.
  • 01:34This was a revolutionary device.
  • 01:37This was the first medical device
  • 01:39that actually used fiber optics.
  • 01:41It was a brilliant device
  • 01:43and and and when we got it,
  • 01:46I was able to talk to the engineers
  • 01:49and and and get all the information
  • 01:51I needed on how to use it.
  • 01:54The third thing that aligned
  • 01:56was this was the height of NASA,
  • 01:59the NASA space program and working
  • 02:01in Colorado at the Institute
  • 02:04where I was was Gene McCullough,
  • 02:07who was a genius programmer who
  • 02:10developed computerized data
  • 02:12acquisition of all Night studies.
  • 02:14In other words,
  • 02:15we we connected the grass device
  • 02:17to a data acquisition system
  • 02:19that he put together and we were
  • 02:22actually able to gather data.
  • 02:24And to analyze it so my life in
  • 02:28Colorado it was it was productive.
  • 02:31And these are some of the
  • 02:32articles that I wrote then,
  • 02:33but I want to just highlight one of them,
  • 02:35which is this one here.
  • 02:37This was by complete coincidence this
  • 02:41article impaired oxygenation during sleep,
  • 02:44and excessive polycythemia of high altitude.
  • 02:47That was the first article printed
  • 02:50in this new journal called Sleep.
  • 02:53The very first article,
  • 02:55and it was just sort of a crazy coincidence.
  • 02:59So also while I was in Colorado,
  • 03:01I had a chance meeting with this
  • 03:04gentleman here Christian Gemino and
  • 03:06those of you who have ever visited Colorado.
  • 03:09Those are the maroon bells.
  • 03:11That's what it actually looks like.
  • 03:13And Christian Gemino was a
  • 03:16neuropsychiatrist from Stanford
  • 03:18and he was there to to to give a
  • 03:21talk on something I had organized a
  • 03:24symposium on control of breathing.
  • 03:27And we spent Christian and I spent a
  • 03:29lot of time just hiking and talking
  • 03:32and what he kind of pointed out to me
  • 03:35was I knew about sleep and breathing,
  • 03:37but I really needed to get much
  • 03:40more involved in the field of
  • 03:43sleep so that and so the term,
  • 03:45by the way,
  • 03:46the term sleep apnea Christian
  • 03:49actually introduced the term,
  • 03:51but he introduced it with
  • 03:53a the wrong condition.
  • 03:55He called it insomnia.
  • 03:57The sleep apnea. A new syndrome.
  • 03:59In fact, his patients did
  • 04:01not have obstructive apnea.
  • 04:02They had central apnea and
  • 04:04I won't get into that.
  • 04:05But that was my first encounter
  • 04:07with someone from Stanford.
  • 04:09Could you say that again?
  • 04:10Oh my God,
  • 04:12my my my phone is going crazy here.
  • 04:15So Christian convinced me to
  • 04:18go to a sleep meeting which
  • 04:21was held in Palo Alto and and
  • 04:24I was the only I'm pretty sure
  • 04:26I was the only pulmonary guy.
  • 04:28At this meeting and and and that
  • 04:30was the prime of Bill Dement,
  • 04:32a you know professor of psychiatry
  • 04:34and and I did my presentation on
  • 04:37sleep at high altitude and Dement
  • 04:39came over to me later on and he said my God,
  • 04:42you're just a kid and the the reality
  • 04:46is is that at that time I was a kid.
  • 04:49So after my training I went off to
  • 04:52Winnipeg for a variety of reasons.
  • 04:55I wanted to go back to Canada
  • 04:57and this is a photograph that
  • 04:59I took actually from the front
  • 05:02porch of our house in.
  • 05:04In in Winnipeg,
  • 05:05and this is the Aurora borealis and
  • 05:07it's just a wonderful thing to see if
  • 05:10you ever have the chance to see it,
  • 05:12but Winnipeg doesn't have
  • 05:13great press because of winters.
  • 05:15So why did I go there, right?
  • 05:17So it had the best pulmonary medicine
  • 05:20section in the country and in Canada.
  • 05:24Who was there?
  • 05:25Ruben Cherniak,
  • 05:26who later on became head of the
  • 05:29National Jewish Hospital for many,
  • 05:30many years.
  • 05:31Nick Antonio says,
  • 05:33so anybody who orders?
  • 05:35Oxygen on a patient might know that
  • 05:38Nick Antonissen was in charge of
  • 05:41the NOT study funded by NIH that
  • 05:44actually documented the benefit
  • 05:46in a double blind study of using
  • 05:49oxygen in patients with COPD.
  • 05:52Larry Wood was there and Larry
  • 05:55eventually wrote one of the great
  • 05:58textbooks of critical care medicine.
  • 06:01So, as I mentioned before,
  • 06:03Nick Antonissen had a lot of.
  • 06:05Had a lot of faith in me and he he
  • 06:08gave me the opportunity to create
  • 06:10the first clinical lab in Canada.
  • 06:13And because there was such a
  • 06:16vibrant pulmonary program,
  • 06:17I was able to do sleep studies and COPD
  • 06:20and there's this your lung disease,
  • 06:23acromegaly,
  • 06:24post polio you know can congestive
  • 06:28heart failure scoliosis you name it?
  • 06:31And the other thing about Winnipeg it's
  • 06:34a great place to raise your family.
  • 06:37OK,
  • 06:37so this is my family so this is from
  • 06:40around that era and a few years later.
  • 06:42So this is my wife Barbara.
  • 06:44This is Shelly this is Michael and
  • 06:47this is Steven and they're all
  • 06:50much bigger now and they're all
  • 06:53successful and this is a typical
  • 06:56picture of a Prairie town with the
  • 06:59grain elevators in the background.
  • 07:02So after I got to Winnipeg before I
  • 07:05had any equipment I had time to kill you,
  • 07:09right grants and then you kind
  • 07:11of waited to get
  • 07:13equipment and I was going to be ultimately
  • 07:15in charge of the second year of pulmonary
  • 07:19program for the medical students.
  • 07:21So I I put a book together and that
  • 07:23was the first book that I did.
  • 07:25Pathophysiology of respiration and I
  • 07:28basically did it for the students.
  • 07:32So after I arrived in Winnipeg,
  • 07:34my role in life changed.
  • 07:38Initially I had these great mentors and
  • 07:42they mentored me and then I became a
  • 07:46mentor and that so my role flipped entirely.
  • 07:50And I had fellows showing up literally from
  • 07:54all over the world from all over the world.
  • 07:58I had fellows who who who appeared
  • 08:01usually with their own funding at
  • 08:04that most of the time there were
  • 08:07no official training programs,
  • 08:09and they came from all sorts of specialties,
  • 08:12neurology, psychiatry, surgery,
  • 08:15ENT, pulmonary cardiology.
  • 08:17And it was really wonderful because all
  • 08:20of a sudden I got to learn from them.
  • 08:22Not just them learning from me.
  • 08:26So my lab became very well known.
  • 08:29This is an so down here.
  • 08:32This is the old Hewlett-Packard
  • 08:34oximetry oximeter.
  • 08:35This is the the grass model 78,
  • 08:39and this guy hears is Prince Phillip.
  • 08:42And so I'm explaining to him how we're
  • 08:47documenting respiratory effort and and
  • 08:49the lab became well known and and.
  • 08:52And there was another fluke
  • 08:54that happened very soon.
  • 08:56After that,
  • 08:57the fluke was that it turned out that
  • 09:00next door to to my lab in in Winnipeg
  • 09:04was something called Manitoba Center
  • 09:06for Health Policy and Evaluation.
  • 09:09Turned out they were the depository
  • 09:13of all the medical data for the
  • 09:16province of over a million people,
  • 09:19so I could obtain data from my
  • 09:21patients and match them to controls.
  • 09:24OK,
  • 09:24and this led to the to a bunch of papers
  • 09:28having to do with healthcare utilization,
  • 09:31and I'll give you just one example of 1.
  • 09:34So this is an example of the are the kind
  • 09:37of data that we were able to to find.
  • 09:39So on this graph,
  • 09:41on the extreme right where
  • 09:43it says evaluation,
  • 09:44that's when I saw my sleep apnea
  • 09:47patients and there were hundreds of them,
  • 09:50and these are female patients,
  • 09:51and I was going to.
  • 09:52I was able to match each patient with four
  • 09:56controls who are either the same weight,
  • 10:00same BMI, or were normal weight
  • 10:03but born roughly on the same date.
  • 10:06OK, so and I was able to look at data.
  • 10:09Going back about 9:00 or 10 years and
  • 10:13what this showed is that the problem
  • 10:16with sleep apnea isn't obesity,
  • 10:19because BMI controls did not have
  • 10:22the same degree of healthcare,
  • 10:25you utilization as the sleep apnea patients.
  • 10:28So that's the kind of research that I did.
  • 10:32And and that was and and.
  • 10:34And that was again because of a
  • 10:37fluke that there was a lab, right?
  • 10:39There was a an office right next to me
  • 10:42that could actually supply that kind of data.
  • 10:46So we're going to go now to 1984.
  • 10:49I was asked to give a talk at the
  • 10:51California Thoracic Society at the Yosemite,
  • 10:55and at that meeting I met Tom Roth.
  • 10:58And and when you're at a place like Yosemite,
  • 11:02you go hiking, you go on.
  • 11:04You have a great time and we
  • 11:06talked and we talked and we talked,
  • 11:09and that led us to work
  • 11:12together on a research project.
  • 11:15Actually, more than one,
  • 11:16and we decided at that meeting
  • 11:19that that a clinical textbook
  • 11:21was needed in the sleep field.
  • 11:23OK, so the study that we collaborated on was
  • 11:27this study here mortality and apnea index,
  • 11:30and obstructive sleep apnea.
  • 11:32So in in the mid 1980s that was
  • 11:36before CPAP was widely available,
  • 11:39or at all in any big numbers.
  • 11:42So at Henry Ford Hospital they had
  • 11:45a large number of untreated apnea
  • 11:47patients that they had been following
  • 11:50for years and years who were not
  • 11:53treated because the only treatment.
  • 11:55At that time,
  • 11:56really was tracheostomy,
  • 11:57which you didn't want to do,
  • 11:59and what this paper showed is that if
  • 12:01you had an apnea index of less than 20,
  • 12:04you didn't die.
  • 12:05If you had an apnea index of more than 20,
  • 12:07you had a pretty good chance of
  • 12:10dying within about 10 years.
  • 12:11Now,
  • 12:12the thing about this paper is
  • 12:14I thought this was really neat
  • 12:15stuff and I submitted it to the
  • 12:17New England Journal of Medicine,
  • 12:19and I got an instantaneous rejection.
  • 12:23It was one of these rejections where
  • 12:26where the the the editor and he
  • 12:28writes me back saying that people are
  • 12:30really not interested in sleep apnea.
  • 12:32Go, you know, go try somewhere else.
  • 12:34So as we resubmitted it to.
  • 12:38To another journal.
  • 12:39So in 1985 we explored the idea of
  • 12:42a textbook and I asked colleagues,
  • 12:45Christian Dimino,
  • 12:46Christian Dimino did not think
  • 12:48there was enough to fill a book,
  • 12:50build them into I.
  • 12:51I I had gone to Stanford and spoke to
  • 12:55Bill and what he said was without a textbook,
  • 12:58you can't have a field.
  • 13:00And so we started to work on the book.
  • 13:04So and and this is really the
  • 13:07last line of of Casablanca.
  • 13:10I think this is the beginning of a
  • 13:13beautiful friendship we worked together
  • 13:15on this book for well over 30 years.
  • 13:18Bill is in the middle and Tom
  • 13:20Roth is on the right and this is
  • 13:22at one of the national meetings,
  • 13:24so the inspiration for the title came so
  • 13:28I've so I mentioned before the library.
  • 13:32So the library at McGill.
  • 13:34Just called the Osler Library.
  • 13:36Osler had been a professor of medicine at
  • 13:40at McGill before he became really famous.
  • 13:43When he moved to the States
  • 13:45and later on went to Oxford.
  • 13:47So the title of the book was going to be
  • 13:50principles and practice of Sleep Medicine.
  • 13:54So this was the 1st edition.
  • 13:56So the 1st edition was broken up
  • 13:59into two parts, normal sleep,
  • 14:02abnormal sleep.
  • 14:03There were a total of about 750
  • 14:08pages and and the book.
  • 14:10Actually it became fairly popular,
  • 14:13came out in about 1989.
  • 14:16So these are all the different
  • 14:18versions of of the book. So
  • 14:238994, 2002, 1005 and and 2011 and.
  • 14:26And show the book changed
  • 14:29it got bigger and bigger.
  • 14:32And and then my family moved to Connecticut.
  • 14:36OK. And I I would have to say so.
  • 14:39First. I was a Gaylord.
  • 14:41I would have to say that
  • 14:43Gale was gutsy to hire me.
  • 14:46I was 64 years old.
  • 14:48And it was sort of gutsy to
  • 14:50hire someone who's 64 years old,
  • 14:52but I guess they saw some value in it
  • 14:55and I worked at the VA where I helped
  • 14:58introduce remote monitoring of CPAP machines,
  • 15:01oral therapy of of sleep apnea and at Yale.
  • 15:05I established a real fellowship
  • 15:07program that had funding that actually
  • 15:10participated in the match and so forth.
  • 15:13Continued scholarly stuff and I and
  • 15:16I started to run an undergraduate.
  • 15:18Course called Mystery of Sleep,
  • 15:20which I'll get back to in a minute.
  • 15:23So we had.
  • 15:25Terrific sleep fellows.
  • 15:27They were an incredibly inspiring
  • 15:29group and in the last few years
  • 15:31we've had about 20 of them,
  • 15:33and they've populated academic centers,
  • 15:35both at Yale Mayo Clinic and and and Duke,
  • 15:39and many have established
  • 15:41clinical practices throughout the
  • 15:44US and outstanding centers.
  • 15:47So during the pandemic it's
  • 15:48hard to give a talk these days
  • 15:50and not mention the pandemic,
  • 15:52so this is what it was like
  • 15:55to mentor students.
  • 15:56And through precept our
  • 15:58fellows during the pandemic.
  • 16:00So you can see me up here in the little
  • 16:03tiny window as I'm talking to the
  • 16:05fellow who has just described the case
  • 16:07to me and and that's how we ended up,
  • 16:10sort of for for basically at least one year,
  • 16:14year and a half doing remote teaching.
  • 16:17During the pandemic of our trainees,
  • 16:20so I also have to say that our sleep
  • 16:24attendings are uninspiring group to me,
  • 16:27an incredible group and I just want
  • 16:29to point out that every time you
  • 16:32see a why with a little bulldog
  • 16:34which is sort of the mascot of Yale.
  • 16:37So these are our faculty members
  • 16:40who actually went through our
  • 16:42Sleep fellowship program.
  • 16:44So I'm very proud of the
  • 16:46fact that that some of our.
  • 16:47Fellows have gotten sort of real jobs,
  • 16:50although I don't know how much
  • 16:52they're making compared to if
  • 16:54they went into private practice,
  • 16:56but they're terrific, terrific people.
  • 17:02So this is the last photograph I was
  • 17:04able to take of the people working in the
  • 17:08clinic itself and and the sleep faculty.
  • 17:11And this is from 2019.
  • 17:13We haven't been able to get the
  • 17:16entire group together like this post
  • 17:19COVID and it really does take a
  • 17:22village to to actually train fellows,
  • 17:25train each other and take real
  • 17:28good care of our patients.
  • 17:30So this is the dream.
  • 17:32I mean, I won't go through all
  • 17:34the people who are on this,
  • 17:36but they're what a great group.
  • 17:39So meanwhile,
  • 17:39while all this is going on,
  • 17:41the 7th edition is coming out right?
  • 17:44So the 7th edition is like way bigger
  • 17:47than what I've showed you before the
  • 17:507th edition of the textbook came out.
  • 17:53Actually, about four months ago,
  • 17:55five months ago,
  • 17:57213 chapter chapters over 2000 pages.
  • 18:02And the book looks like this on on the right.
  • 18:05So the 6th edition looks like
  • 18:07this 7th edition looks like that,
  • 18:10and I I'd like to actually mention a
  • 18:13couple of things about the 7th edition.
  • 18:18So so we Kathy Goldstein is became.
  • 18:24One of the terrific sort of
  • 18:28senior editors of the book and and
  • 18:32hopefully she will continue taking
  • 18:34the book forward into the future.
  • 18:38And I I was delighted to learn
  • 18:40that just this week she has been
  • 18:42promoted to full professor at the
  • 18:45University of Michigan.
  • 18:49So during the book, during the creation
  • 18:51of the book, there was a huge.
  • 18:55I'm I'm I'm gonna say the efforts put forth
  • 18:58by by the section editors were phenomenal
  • 19:02and so I listed the all of the editors.
  • 19:06All the section editors there was one for
  • 19:09neurology, one for movement disorders,
  • 19:11one for pulmonary,
  • 19:12one for cardiovascular, and so forth.
  • 19:16They did a tremendous,
  • 19:18tremendous, tremendous job,
  • 19:20and Bill Dement died and Bill Dement died.
  • 19:25I guess it would be about almost
  • 19:28two years ago now and that was
  • 19:30a huge shock and and he wasn't.
  • 19:32I mean, I mean,
  • 19:34he was really the inspiration for me to
  • 19:38start on the books in the first place.
  • 19:41Putting out a book during a pandemic.
  • 19:44I gotta tell you was a real struggle.
  • 19:48There were five authors who died during
  • 19:52during the creation of this book,
  • 19:54who would have contributed to the book.
  • 19:57A Christian demino also died.
  • 20:00And so it it, it was a.
  • 20:02It was a very tough thing to
  • 20:06actually get it done,
  • 20:08but it we had to get it done
  • 20:10and we did get it done.
  • 20:13And and with thanks to all the
  • 20:16section editors and and Kathy.
  • 20:19So I mentioned before that I teach
  • 20:22a class and this is a photograph of
  • 20:25the students that I had in in 2018
  • 20:27and mystery of sleep class and I love
  • 20:31teaching the undergraduates why?
  • 20:34Because they're so smart that it's
  • 20:38actually frightening. So that's me.
  • 20:40And the yellow jacket and and Doctor
  • 20:42Suen bottom, who is Co instructors back here.
  • 20:45You can barely see him.
  • 20:47I mean the.
  • 20:49These students were so inspiring I could.
  • 20:52I could take an hour to explain
  • 20:54to you some of their their their
  • 20:57achievements incredible.
  • 20:58So I also did some books for the
  • 21:02public and I won't spend a whole
  • 21:05lot of time talking about them.
  • 21:08But one of the things that that.
  • 21:11I always love to do was to take
  • 21:13care of patients, manage patients.
  • 21:15And it has been an honor for me
  • 21:18to be able to treat probably more
  • 21:21than 50,000 patients in my career.
  • 21:25And a lot of what I have learned about sleep,
  • 21:29about diseases about humanity
  • 21:33have been from my patients.
  • 21:37So I'm gonna end now by talking
  • 21:40about the things that shaped me.
  • 21:43And hopefully there'll be
  • 21:44some time for comments.
  • 21:46Mother,
  • 21:46my mother and and I guess it's
  • 21:50genes genetics, the love of writing.
  • 21:53My father, the love of art.
  • 21:56And and my and I've actually written
  • 21:58a book called Sleep and Art,
  • 22:00and that's again a genetic thing.
  • 22:04I was shaped by my spouse who
  • 22:06really taught me about loving life.
  • 22:09And my children.
  • 22:11Unwavering support, I mean,
  • 22:13during the the the years when they
  • 22:15were young and I was in the basement
  • 22:17working on talks, working on books.
  • 22:19They never ever said.
  • 22:21You know that we need to go
  • 22:23and play baseball or something.
  • 22:25They were incredibly supportive.
  • 22:29So what a career needs
  • 22:32is champions and mentors who believe in you.
  • 22:36Who lets you do what you want to do,
  • 22:39not what they want you to
  • 22:42do and take over their work?
  • 22:44You gotta. They have got to.
  • 22:47Express themselves, you need to have
  • 22:51a passion about what you are doing.
  • 22:52You gotta love what you are doing.
  • 22:55You have to have a supportive family.
  • 22:58You have to have patience because some
  • 23:01of the things that you do may take
  • 23:04a year or 30 years for that matter.
  • 23:08And of course serendipity.
  • 23:11You need serendipity.
  • 23:13So I'm going to end now with
  • 23:16the last part of of a poem that
  • 23:20I love by Robert Frost.
  • 23:24I shall be telling this with a sigh
  • 23:27somewhere ages and ages, hence.
  • 23:28Two roads diverged in a wood and I
  • 23:32I took the one less traveled by.
  • 23:36And that has made all the difference.
  • 23:39Thank you.
  • 23:44Thank you so much, Doctor Krieger,
  • 23:46that was really wonderful and I'm
  • 23:48going to cry now even even as you are.
  • 23:50So I think if we hadn't if the
  • 23:52audience of everyone could hear,
  • 23:54I think we'd have a amazing round
  • 23:56of applause and a standing ovation.
  • 23:58Amazing comments in the chat.
  • 24:00Thanking you for sharing your journey.
  • 24:03I would like to invite people
  • 24:04to ask any questions you have.
  • 24:06Any questions they have so far I'm
  • 24:09just seeing great, great comments and.
  • 24:12Wonderful things, what you know.
  • 24:13I would say you know having a career
  • 24:15like this and you know going back
  • 24:17when you're so young and training.
  • 24:19And then as you move forward in your career,
  • 24:22there are a lot of.
  • 24:23There are a lot of forks in the road
  • 24:24as you mentioned, a lot of changes.
  • 24:26Sometimes they're stumbling blocks.
  • 24:28How do you keep moving forward?
  • 24:30You know some of our mentees will
  • 24:31ask you know, what do you do?
  • 24:34Sometimes things just don't work.
  • 24:35How do you maintain that enthusiasm?
  • 24:37How do you maintain that interest?
  • 24:38How do you maintain that curiosity
  • 24:40in those times that?
  • 24:41Like you said,
  • 24:42there's many rejections right
  • 24:44from these journals, et cetera.
  • 24:45So maybe you can speak to that.
  • 24:48Well, I you know the.
  • 24:51The child of Holocaust survivors.
  • 24:55And what you learn is a sense of resilience.
  • 24:59What you learn is that you don't give up.
  • 25:03You continue on your journey
  • 25:05whatever the journey is and and you.
  • 25:08If you have a destination, you go to it.
  • 25:11In other words,
  • 25:12you know having a paper rejected.
  • 25:15Some people would say it's the worst
  • 25:17thing that can possibly happen.
  • 25:18Sometimes it's the best thing
  • 25:21that can possibly happen.
  • 25:23You know, you know, as an example,
  • 25:26I have reviewed papers written by
  • 25:29colleagues of mine, which were terrible.
  • 25:33And I rejected them and and
  • 25:34why did I reject them?
  • 25:36Because they the papers.
  • 25:38If they had published,
  • 25:40would have made the authors look bad.
  • 25:43In other words,
  • 25:44you try to help people.
  • 25:46And sometimes the best way to help
  • 25:48people is to tell them you can do better.
  • 25:51You can do better and and that
  • 25:54I think is is an important,
  • 25:56very important lesson that that you learn
  • 26:00something every time you you have been.
  • 26:03Told that it's not good enough and and
  • 26:06the other thing I I'd like to mention
  • 26:09is that in in in I mean people in
  • 26:11medicine generally are good folks.
  • 26:13They have a heart and don't ever be
  • 26:16afraid of going to like the most famous
  • 26:19guy in the world and and contacting
  • 26:22them with a question or or or if you
  • 26:25have some concern about something,
  • 26:27they will respond to you and
  • 26:29with the Internet it's it's.
  • 26:31It's crazy easy.
  • 26:33To actually develop a relationship with
  • 26:36someone because you never know where
  • 26:39that relationship is going to take you,
  • 26:41it might take you nowhere,
  • 26:43but it may take you somewhere terrific,
  • 26:46so so resilience and and and you know,
  • 26:51keeping the destination insight and
  • 26:53and I'll tell you there are times when
  • 26:56people realize that the course that
  • 26:59they're taking is the wrong one for them.
  • 27:03In other words,
  • 27:04very early in in life I I,
  • 27:06I suddenly realized that I'm never
  • 27:09going to be a neurosurgeon.
  • 27:12I could have gone into neurosurgery
  • 27:14and sort of failed at it or
  • 27:16not be very good at it,
  • 27:17but I I corrected my course
  • 27:20for whatever that's worth.
  • 27:23That's terrific, yeah.
  • 27:24If you can't build a house right?
  • 27:26You can't become a neurosurgeon.
  • 27:27So you obviously learned we do have a
  • 27:30question about what's next for you.
  • 27:31If you're comfortable sharing that,
  • 27:33well, I mean, what's next for me
  • 27:36is I'm doing is I'm going to being
  • 27:38an emeritus at Yale, allows you to
  • 27:41to teach to teach undergraduates,
  • 27:43so I'm going to continue to teach
  • 27:46the mystery of sleep course and and,
  • 27:49and that is extremely gratifying.
  • 27:52The number of students is gonna
  • 27:55this year is gonna be about 70
  • 27:58and and between 60 and 70.
  • 28:01I'm going to love doing that and there are
  • 28:04a few books that are brewing in my head.
  • 28:07As we speak there,
  • 28:08there are a couple of books that are
  • 28:10in the final stages of production.
  • 28:12I see doctor Steven Sheldon is
  • 28:14is on here and Steve,
  • 28:16Steven and and I are are shepherding.
  • 28:19Actually mostly Steven are shepherding
  • 28:22a pediatric sleep textbook,
  • 28:24which I think is sort of almost finished
  • 28:27and and so that's one of the projects.
  • 28:30There's a.
  • 28:31There's a an Atlas of Sleep Medicine
  • 28:33that I'm working on that's going
  • 28:35to be finished in the next year.
  • 28:37And I'm still interested in art and
  • 28:40and I'm gonna try to recover all
  • 28:42the time lost during the pandemic.
  • 28:44There are a lot of people I
  • 28:46haven't seen sort of in in, in,
  • 28:49in person and I need to reestablish them.
  • 28:53Some of that relatives in in in Europe
  • 28:58and and and elsewhere you know,
  • 29:01until about a month ago I hadn't seen my
  • 29:03own sister in in more than two years.
  • 29:06Hadn't seen her in 2 1/2 years.
  • 29:08And so I'm going to try to kind
  • 29:10of recover some of the lost time.
  • 29:15Alright, that's that's wonderful.
  • 29:16Wonderful for you again.
  • 29:18A lot of great comments.
  • 29:19A lot of this has been fabulous,
  • 29:21inspirational and everybody
  • 29:24appreciates what you're sharing.
  • 29:25If anyone would like to either
  • 29:26put a message in the chat,
  • 29:28or if you would like to
  • 29:30unmute yourself I can give you
  • 29:32permission to do that and then
  • 29:34ask any questions that you have.
  • 29:36I'd be I'd be happy to do that.
  • 29:39You have permission if you'd like.
  • 29:42I think Naftali just raised his
  • 29:43hand or somebody raised their hand.
  • 29:47Yeah, so of course. Thank you mayor, it's.
  • 29:54Really amazing talk and
  • 29:56inspiring and as always,
  • 29:58also just interesting and and the book.
  • 30:04Umm? I haven't opened the book.
  • 30:08But I do enjoy looking at the cover.
  • 30:10It's so beautiful and I
  • 30:12promise also to look inside.
  • 30:14I'm sure it's amazing.
  • 30:15I do want to mention that this
  • 30:17doesn't get you off the hook.
  • 30:19You will have to return to Yale.
  • 30:20Give a talk in person,
  • 30:22go through a reception and all the
  • 30:25people on this talk are invited,
  • 30:27so make sure that you stay tuned
  • 30:30because it's going to be hybrid
  • 30:32so you don't have to come.
  • 30:33But again,
  • 30:34we'll be glad to come and and I
  • 30:37also will take this advantage
  • 30:39to mention the June 1st.
  • 30:41We have a sort of another
  • 30:43farewell to a local giant.
  • 30:45Vahid Mossanen will give a pulmonary
  • 30:47grand rounds and we'll have a reception.
  • 30:49So again, everybody's invited.
  • 30:53This is sort of a change in.
  • 30:55Of.
  • 30:56I literally understand now the verse of
  • 30:59standing on the shoulders of giants.
  • 31:01You know,
  • 31:02because when you get to meet giants?
  • 31:05And recognize it you understand we are
  • 31:07all of us are really on your shoulders.
  • 31:09So thank you,
  • 31:10mayor.
  • 31:12So I see that Jill Lavine so Gil
  • 31:17was the Dean of of a dental school
  • 31:22in Montreal University Of Montreal.
  • 31:24So digital. Through here mirror
  • 31:28I have. I hope, now that
  • 31:29two challenging question,
  • 31:30but with all your background experience and
  • 31:32the vision you always add in the future,
  • 31:35what is the biggest challenge for
  • 31:37our student for our young doctor?
  • 31:40Young dentist in Sleep Medicine?
  • 31:42Do you see something which should
  • 31:45work to as a group to improve?
  • 31:49Challenge the defeat.
  • 31:51Yeah, I think the major challenge
  • 31:55for the field going forward
  • 31:57that there are two challenges.
  • 31:59One of the challenges is really access.
  • 32:02There there is so much inequity in
  • 32:06in medicine still that only certain
  • 32:09you know that there are so many
  • 32:13disadvantaged people who never
  • 32:15have their sleep problem diagnosed
  • 32:18properly and treated properly.
  • 32:20So access is a huge huge issue and the
  • 32:24other thing that I think is going to become.
  • 32:27Very big in the future is combining
  • 32:30some of the newer technologies,
  • 32:32maybe genetic testing and and
  • 32:34and so forth in in, in the in,
  • 32:38in the management of patients with sleep
  • 32:41disorders and and in terms of dentistry.
  • 32:45I think whenever someone sees a patient
  • 32:48in the clinic you got to ask them about
  • 32:53their children because of very large
  • 32:56percentage of the patients that we see.
  • 32:59With sleep apnea,
  • 33:00who are like 50 years old will have a
  • 33:03child who's like 10 or 11 and if that
  • 33:05child snores or has a sleep problem,
  • 33:08they need to be treated in order
  • 33:10to avoid them developing the
  • 33:12sleep disorder later on in life.
  • 33:15So I think those are some of
  • 33:17the big challenges.
  • 33:19Mercy vocal, thank you very
  • 33:21much ma'am. You're welcome.
  • 33:25Anyone asking any comments?
  • 33:28So Adrian from London
  • 33:30yes, mayor again like everyone's sentiment.
  • 33:35How absolutely wonderful.
  • 33:38I guess some of us of a similar age would
  • 33:41been through similar things, but uh,
  • 33:44can't put them together quite so eloquently.
  • 33:46But then you graced us in London
  • 33:49with your time and the sabbatical,
  • 33:52but a small center called
  • 33:54guys and Saint Thomas.
  • 33:56So do you think there's stuff that
  • 33:59can be done in other places that would
  • 34:02help this journey to understand sleep
  • 34:06well? Who knows that maybe I'll return to.
  • 34:09To to? I mean, you're being very
  • 34:11modest guys in the Saint Thomas,
  • 34:14I think together are like,
  • 34:16aren't they like the biggest
  • 34:18Medical Center in Europe?
  • 34:20And sleep center your ideas.
  • 34:21OK, so you're you're overly modest and
  • 34:25the sleep clinic in London was wonderful.
  • 34:29The staff was was just wonderful and the
  • 34:32research going on there was was terrific.
  • 34:34And you know, maybe one day I'll go back
  • 34:37and and hang out with you guys again.
  • 34:40We'll look forward
  • 34:41to that. Thank you mayor again,
  • 34:42and wonderful lovely thank you.
  • 34:45Thank you everyone so much for coming.
  • 34:47I think mayor this has
  • 34:49been absolutely wonderful.
  • 34:50I appreciate everyone for attending
  • 34:53and all of your comments.
  • 34:54Hopefully we can save the chat
  • 34:56so that way you can see it.
  • 34:58Thank you everyone mayor.
  • 34:59Thank you so much for sharing your story.
  • 35:02Thank you.
  • 35:03Have a wonderful day everyone.