CPIRT Publications

2023

Mature B cells and mesenchymal stem cells control emergency myelopoiesis.Lim VY, Feng X, Miao R, Zehentmeier S, Ewing-Crystal N, Lee M, Tumanov AV, Oh JE, Iwasaki A, Wang A, Choi J, Pereira JP. Life Sci Alliance. 2023 Apr; 2023 Jan 30. PMID: 36717247.
Identification of Efflux Substrates Using a Riboswitch-Based Reporter in Pseudomonas aeruginosa.Urdaneta-Páez V, Hamchand R, Anthony K, Crawford J, Sutherland AG, Kazmierczak BI. mSphere. 2023 Mar 22; 2023 Mar 22. PMID: 36946743.
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms.Taghi Khani A, Kumar A, Sanchez Ortiz A, Radecki KC, Aramburo S, Lee SJ, Hu Z, Damirchi B, Lorenson MY, Wu X, Gu Z, Stohl W, Sanz I, Meffre E, Müschen M, Forman SJ, Koff JL, Walker AM, Swaminathan S. Commun Biol. 2023 Mar 20; 2023 Mar 20. PMID: 36941341.
Adaptation of Nontypeable Haemophilus influenzae in Human Airways in COPD: Genome Rearrangements and Modulation of Expression of HMW1 and HMW2.Murphy TF, Kirkham C, D'Mello A, Sethi S, Pettigrew MM, Tettelin H. mBio. 2023 Mar 16; 2023 Mar 16. PMID: 36927061.
The Coxiella burnetii effector EmcB is a deubiquitinase that inhibits RIG-I signaling.Duncan-Lowey J, Crabill E, Jarret A, Reed SCO, Roy CR. Proc Natl Acad Sci U S A. 2023 Mar 14; 2023 Mar 9. PMID: 36893270.
Covid-19 vaccine acceptance among individuals incarcerated in Connecticut state jails.Lind ML, Kennedy BS, Nieto MD, Houde AJ, Sosensky P, Borg R, Cummings DAT, Ko AI, Richeson RP. Health Justice. 2023 Mar 13; 2023 Mar 13. PMID: 36913159.
SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity.Jaycox JR, Lucas C, Yildirim I, Dai Y, Wang EY, Monteiro V, Lord S, Carlin J, Kita M, Buckner JH, Ma S, Campbell M, Ko A, Omer S, Lucas CL, Speake C, Iwasaki A, Ring AM. Nat Commun. 2023 Mar 9; 2023 Mar 9. PMID: 36894554.
Type 2 Dendritic Cells Orchestrate a Local Immune Circuit to Confer Antimetastatic Immunity.Weizman OE, Luyten S, Krykbaeva I, Song E, Mao T, Bosenberg M, Iwasaki A. J Immunol. 2023 Mar 3; 2023 Mar 3. PMID: 36881866.
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection.Wei J, Patil A, Collings CK, Alfajaro MM, Liang Y, Cai WL, Strine MS, Filler RB, DeWeirdt PC, Hanna RE, Menasche BL, Ökten A, Peña-Hernández MA, Klein J, McNamara A, Rosales R, McGovern BL, Luis Rodriguez M, García-Sastre A, White KM, Qin Y, Doench JG, Yan Q, Iwasaki A, Zwaka TP, Qi J, Kadoch C, Wilen CB. Nat Genet. 2023 Mar; 2023 Mar 9. PMID: 36894709.
Response to: Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect.Takahashi T, Stoiljkovic M, Song E, Gao XB, Yasumoto Y, Kudo E, Carvalho F, Kong Y, Park A, Shanabrough M, Szigeti-Buck K, Liu ZW, Kristant A, Zhang Y, Sulkowski P, Glazer PM, Kaczmarek LK, Horvath TL, Iwasaki A. Neuron. 2023 Mar 1. PMID: 36863323.
NLRX1 knockdown attenuates pro-apoptotic signaling and cell death in pulmonary hyperoxic acute injury.Kim HR, Kim MN, Kim EG, Leem JS, Baek SM, Lee YJ, Kim KW, Kang MJ, Song TW, Sohn MH. Sci Rep. 2023 Mar 1; 2023 Mar 1. PMID: 36859435.
Use of Whole-Genome Sequencing to Estimate the Contribution of Immune Evasion and Waning Immunity on Decreasing COVID-19 Vaccine Effectiveness.Lind ML, Copin R, McCarthy S, Coppi A, Warner F, Ferguson D, Duckwall C, Borg R, Muenker MC, Overton J, Hamon S, Zhou A, Cummings DAT, Ko AI, Hamilton JD, Schulz WL, Hitchings MDT. J Infect Dis. 2023 Mar 1. PMID: 36408616.
Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection.Ganesan S, Alvarez NN, Steiner S, Fowler KM, Corona AK, Roy CR. mBio. 2023 Feb 28; 2023 Feb 2. PMID: 36728431.
Magnetic bead-based separation of pneumococcal serotypes.York A, Huynh E, Mbodj S, Yolda-Carr D, Hislop MS, Echlin H, Rosch JW, Weinberger DM, Wyllie AL. Cell Rep Methods. 2023 Feb 27; 2023 Feb 21. PMID: 36936076.
The COVID-19 pandemic as an opportunity for unravelling the causative association between respiratory viruses and pneumococcus-associated disease in young children: a prospective study.Dagan R, van der Beek BA, Ben-Shimol S, Greenberg D, Shemer-Avni Y, Weinberger DM, Danino D. EBioMedicine. 2023 Feb 27; 2023 Feb 27. PMID: 36857965.
Direct and indirect mortality impacts of the COVID-19 pandemic in the United States, March 1, 2020 to January 1, 2022.Lee WE, Woo Park S, Weinberger DM, Olson D, Simonsen L, Grenfell BT, Viboud C. Elife. 2023 Feb 22; 2023 Feb 22. PMID: 36811598.
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.Ahangari F, Price NL, Malik S, Chioccioli M, Bärnthaler T, Adams TS, Kim J, Pradeep SP, Ding S, Cosmos C Jr, Rose KS, McDonough JE, Aurelien NR, Ibarra G, Omote N, Schupp JC, DeIuliis G, Villalba Nunez JA, Sharma L, Ryu C, Dela Cruz CS, Liu X, Prasse A, Rosas I, Bahal R, Fernández-Hernando C, Kaminski N. JCI Insight. 2023 Feb 22; 2023 Feb 22. PMID: 36626225.
Age-dependent impairment in antibody responses elicited by a homologous CoronaVac booster dose.Filardi BA, Monteiro VS, Schwartzmann PV, do Prado Martins V, Zucca LER, Baiocchi GC, Malik AA, Silva J, Hahn AM, Chen NFG, Pham K, Pérez-Then E, Miric M, Brache V, Cochon L, Larocca RA, Mendez RDR, Bardini Silveira D, Pinto AR, Croda J, Yildirim I, Omer SB, Ko AI, Vermund SH, Grubaugh ND, Iwasaki A, Lucas C, Vogels CBF, Breban M, Koch TR, Chaguza C, Tikhonova I, Castaldi C, Mane S, De Kumar B, Ferguson D, Kerantzas N, Peaper D, Landry ML, Schulz W. Sci Transl Med. 2023 Feb 15; 2023 Feb 15. PMID: 36791210.
Coronaviruses, Lysosomes, and Secondary Bacterial Infections: Coronaviruses Outsmart the Host.Peng X, Dela Cruz CS, Sharma L. DNA Cell Biol. 2023 Feb 10; 2023 Feb 10. PMID: 36763591.
Nonutility of procalcitonin for diagnosing bacterial pneumonia in patients with severe COVID-19.Cohen AJ, Glick LR, Lee S, Kunitomo Y, Tsang DA, Pitafi S, Valda Toro P, Ristic NR, Zhang E, Carey GB, Datta R, Dela Cruz CS, Gautam S. Eur Clin Respir J. 2023; 2023 Feb 8. PMID: 36815942.
Testing Frequency Matters: An Evaluation of the Diagnostic Performance of a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Rapid Antigen Test in US Correctional Facilities.Lind ML, Schultes OL, Robertson AJ, Houde AJ, Cummings DAT, Ko AI, Kennedy BS, Richeson RP. Clin Infect Dis. 2023 Feb 8. PMID: 35686341.
Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti-PD-1 Immunotherapy in Endometrial Carcinoma.Chow RD, Michaels T, Bellone S, Hartwich TMP, Bonazzoli E, Iwasaki A, Song E, Santin AD. Cancer Discov. 2023 Feb 6. PMID: 36301137.
Routine saliva testing for SARS-CoV-2 in children: Methods for partnering with community childcare centers.Rayack EJ, Askari HM, Zirinsky E, Lapidus S, Sheikha H, Peno C, Kazemi Y, Yolda-Carr D, Liu C, Grubaugh ND, Ko AI, Wyllie AL, Spatz ES, Oliveira CR, Bei AK. Front Public Health. 2023; 2023 Feb 3. PMID: 36817891.
Platelet response to influenza vaccination reflects effects of aging.Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins TP, Belshe RB, Chawla DG, Rondina MT, Gill TM, Montgomery RR, Allore HG, Kleinstein SH, Shaw AC. Aging Cell. 2023 Feb; 2023 Jan 19. PMID: 36656789.
Glucocorticoid Therapy in COVID-19.Amati F, Tonutti A, Huston J, Dela Cruz CS. Semin Respir Crit Care Med. 2023 Feb; 2023 Jan 16. PMID: 36646089.
COVID-19.Dela Cruz CS, Feldman C. Semin Respir Crit Care Med. 2023 Feb; 2023 Jan 16. PMID: 36646080.
Correction to: Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb. PMID: 36565380.
Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb; 2022 Nov 19. PMID: 36401063.
PD-1(high)CXCR5(-)CD4(+) peripheral helper T cells promote CXCR3(+) plasmablasts in human acute viral infection.Asashima H, Mohanty S, Comi M, Ruff WE, Hoehn KB, Wong P, Klein J, Lucas C, Cohen I, Coffey S, Lele N, Greta L, Raddassi K, Chaudhary O, Unterman A, Emu B, Kleinstein SH, Montgomery RR, Iwasaki A, Dela Cruz CS, Kaminski N, Shaw AC, Hafler DA, Sumida TS. Cell Rep. 2023 Jan 31; 2023 Jan 2. PMID: 36596303.
Identification of two specific transcriptomic clusters of COVID-19 acute respiratory distress syndrome patients with different immune profiles and different outcomes.Shindo Y, Dela Cruz CS, Witzenrath M. Eur Respir J. 2023 Jan; 2023 Jan 27. PMID: 36517181.
COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation.Patton MJ, Orihuela CJ, Harrod KS, Bhuiyan MAN, Dominic P, Kevil CG, Fort D, Liu VX, Farhat M, Koff JL, Lal CV, Gaggar A, Richter RP, Erdmann N, Might M, Gaggar A. Crit Care. 2023 Jan 23; 2023 Jan 23. PMID: 36691080.
Waning Effectiveness of the BNT162b2 Vaccine Against Infection in Adolescents in Israel.Prunas O, Weinberger DM, Pitzer VE, Gazit S, Patalon T. Clin Infect Dis. 2023 Jan 6. PMID: 36484301.
Choice Architecture to Assist Clinicians with Appropriate COVID-19 Test Ordering.Sangal RB, Venkatesh AK, Cahill J, Pettker CM, Peaper DR. J Appl Lab Med. 2023 Jan 4. PMID: 36610419.
Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells.Tyagi T, Jain K, Yarovinsky TO, Chiorazzi M, Du J, Castro C, Griffin J, Korde A, Martin KA, Takyar SS, Flavell RA, Patel AA, Hwa J. J Exp Med. 2023 Jan 2; 2022 Oct 28. PMID: 36305874.
Reflections for the 50th Anniversary of The Journal of Rheumatology: The Past, Present, and Future of Rheumatology.Masi AT, Bucala RJ. J Rheumatol. 2023 Jan. PMID: 36587952.
Nasal host response-based screening for undiagnosed respiratory viruses: a pathogen surveillance and detection study.Cheemarla NR, Hanron A, Fauver JR, Bishai J, Watkins TA, Brito AF, Zhao D, Alpert T, Vogels CBF, Ko AI, Schulz WL, Landry ML, Grubaugh ND, van Dijk D, Foxman EF. Lancet Microbe. 2023 Jan. PMID: 36586415.
IFN-γ Is Protective in Cytokine Release Syndrome-associated Extrapulmonary Acute Lung Injury.Sun Y, Hu B, Stanley G, Harris ZM, Gautam S, Homer R, Koff JL, Rajagopalan G. Am J Respir Cell Mol Biol. 2023 Jan. PMID: 36125351.
Adding Insult to Injury: Does COVID-19 Promote Acute Respiratory Distress Syndrome by Inhibiting Surfactant?Richmond BW, Dela Cruz CS. Am J Respir Crit Care Med. 2023 Jan 1. PMID: 35976979.

2022

Inhaled Bacteriophage Therapy for Multi-Drug Resistant Achromobacter.Winzig F, Gandhi S, Lee A, Würstle S, Stanley GL, Capuano I, Neuringer I, Koff JL, Turner PE, Chan BK. Yale J Biol Med. 2022 Dec; 2022 Dec 22. PMID: 36568830.
Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein.Lapidus S, Liu F, Casanovas-Massana A, Dai Y, Huck JD, Lucas C, Klein J, Filler RB, Strine MS, Sy M, Deme AB, Badiane AS, Dieye B, Ndiaye IM, Diedhiou Y, Mbaye AM, Diagne CT, Vigan-Womas I, Mbengue A, Sadio BD, Diagne MM, Moore AJ, Mangou K, Diallo F, Sene SD, Pouye MN, Faye R, Diouf B, Nery N Jr, Costa F, Reis MG, Muenker MC, Hodson DZ, Mbarga Y, Katz BZ, Andrews JR, Campbell M, Srivathsan A, Kamath K, Baum-Jones E, Faye O, Sall AA, Vélez JCQ, Cappello M, Wilson M, Ben-Mamoun C, Tedder R, McClure M, Cherepanov P, Somé FA, Dabiré RK, Moukoko CEE, Ouédraogo JB, Boum Y 2nd, Shon J, Ndiaye D, Wisnewski A, Parikh S, Iwasaki A, Wilen CB, Ko AI, Ring AM, Bei AK. Sci Rep. 2022 Dec 22; 2022 Dec 22. PMID: 36550362.
Impact of Temporary Storage Conditions on the Viability of Streptococcus pneumoniae in Saliva.Allicock OM, York A, Waghela P, Yolda-Carr D, Weinberger DM, Wyllie AL. mSphere. 2022 Dec 21; 2022 Nov 21. PMID: 36409104.
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Am J Respir Crit Care Med. 2022 Dec 15. PMID: 35998281.
Leptospira Infection in Rural Areas of Urabá Region, Colombia: A Prospective Study.Quintero-Vélez JC, Rodas JD, Rojas CA, Ko AI, Wunder EA. Am J Trop Med Hyg. 2022 Dec 14; 2022 Nov 14. PMID: 36375452.
Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis.Öz HH, Cheng EC, Di Pietro C, Tebaldi T, Biancon G, Zeiss C, Zhang PX, Huang PH, Esquibies SS, Britto CJ, Schupp JC, Murray TS, Halene S, Krause DS, Egan ME, Bruscia EM. Cell Rep. 2022 Dec 13. PMID: 36516754.
Why is leptospirosis hard to avoid for the impoverished? Deconstructing leptospirosis transmission risk and the drivers of knowledge, attitudes, and practices in a disadvantaged community in Salvador, Brazil.Palma FAG, Costa F, Lustosa R, Mogaji HO, de Oliveira DS, Souza FN, Reis MG, Ko AI, Begon M, Khalil H. PLOS Glob Public Health. 2022; 2022 Dec 9. PMID: 36962720.
Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case-control analysis.Lind ML, Robertson AJ, Silva J, Warner F, Coppi AC, Price N, Duckwall C, Sosensky P, Di Giuseppe EC, Borg R, Fofana MO, Ranzani OT, Dean NE, Andrews JR, Croda J, Iwasaki A, Cummings DAT, Ko AI, Hitchings MDT, Schulz WL. PLoS Med. 2022 Dec; 2022 Dec 1. PMID: 36454733.
Cystic Fibrosis in the Era of Highly Effective CFTR Modulators.Britto CJ, Taylor-Cousar JL. Clin Chest Med. 2022 Dec. PMID: 36344084.
Non-Modulator Therapies: Developing a Therapy for Every Cystic Fibrosis Patient.Egan ME. Clin Chest Med. 2022 Dec. PMID: 36344076.
Novel Approaches to Multidrug-Resistant Infections in Cystic Fibrosis.Murray TS, Stanley G, Koff JL. Clin Chest Med. 2022 Dec. PMID: 36344073.
Emerging Approaches to Monitor and Modify Care in the Era of Cystic Fibrosis Transmembrane Conductance Regulators.Britto CJ, Ratjen F, Clancy JP. Clin Chest Med. 2022 Dec. PMID: 36344071.
Update on Innate and Adaptive Immunity in Cystic Fibrosis.Bruscia EM, Bonfield TL. Clin Chest Med. 2022 Dec. PMID: 36344069.
Assessment of polymicrobial interactions in bacterial isolates from transfused platelet units associated with sepsis.Kerantzas CA, Merwede J, Snyder EL, Hendrickson JE, Tormey CA, Kazmierczak BI, Peaper DR. Transfusion. 2022 Dec; 2022 Sep 30. PMID: 36178430.
Reliable estimation of SARS-CoV-2 anti-spike protein IgG titers from single dilution optical density values in serologic surveys.Andrade Belitardo EMM, Nery N Jr, Aguilar Ticona JP, Portilho MM, Mello IO, Ribeiro GS, Reis MG, Costa F, Cummings DAT, Ko AI, Fofana MO. Diagn Microbiol Infect Dis. 2022 Dec; 2022 Aug 31. PMID: 36162285.
Impact of antibiotics on off-target infant gut microbiota and resistance genes in cohort studies.Lebeaux RM, Madan JC, Nguyen QP, Coker MO, Dade EF, Moroishi Y, Palys TJ, Ross BD, Pettigrew MM, Morrison HG, Karagas MR, Hoen AG. Pediatr Res. 2022 Dec; 2022 May 14. PMID: 35568730.
Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells.Kantrong N, Chang AM, Bamashmous S, Hajjar AM, Bucala RJ, Darveau RP. J Periodontol. 2022 Dec; 2022 Feb 24. PMID: 35100435.
VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis.Kim SH, Adams TS, Hu Q, Shin HJ, Chae G, Lee SE, Sharma L, Kwon HK, Lee FY, Park HJ, Huh WJ, Manning E, Kaminski N, Sauler M, Chen L, Song JW, Kim TK, Kang MJ. Am J Respir Cell Mol Biol. 2022 Nov 30; 2022 Nov 30. PMID: 36450109.
Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses.Mao T, Israelow B, Peña-Hernández MA, Suberi A, Zhou L, Luyten S, Reschke M, Dong H, Homer RJ, Saltzman WM, Iwasaki A. Science. 2022 Nov 25; 2022 Nov 25. PMID: 36302057.
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration.Fiedler S, Devenish SRA, Morgunov AS, Ilsley A, Ricci F, Emmenegger M, Kosmoliaptsis V, Theel ES, Mills JR, Sholukh AM, Aguzzi A, Iwasaki A, Lynn AK, Knowles TPJ. Sci Rep. 2022 Nov 17; 2022 Nov 17. PMID: 36396691.
Corrigendum: Escape of TLR5 recognition by Leptospira spp.: A rationale for atypical endoflagella.Holzapfel M, Bonhomme D, Cagliero J, Vernel-Pauillac F, d'Andon MF, Bortolussi S, Fiette L, Goarant C, Wunder EA Jr, Picardeau M, Ko AI, Werling D, Matsui M, Boneca IG, Werts C. Front Immunol. 2022; 2022 Nov 8. PMID: 36439189.
Predicting vaccine effectiveness against invasive pneumococcal disease in children using immunogenicity data.Ryman J, Weaver J, Hu T, Weinberger DM, Yee KL, Sachs JR. NPJ Vaccines. 2022 Nov 7; 2022 Nov 7. PMID: 36344529.
The neurobiology of long COVID.Monje M, Iwasaki A. Neuron. 2022 Nov 2; 2022 Oct 7. PMID: 36288726.
CD74 as a regulator of transcription in normal B cells.David K, Friedlander G, Pellegrino B, Radomir L, Lewinsky H, Leng L, Bucala R, Becker-Herman S, Shachar I. Cell Rep. 2022 Nov 1. PMID: 36323260.
Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia.Bernard-Raichon L, Venzon M, Klein J, Axelrad JE, Zhang C, Sullivan AP, Hussey GA, Casanovas-Massana A, Noval MG, Valero-Jimenez AM, Gago J, Putzel G, Pironti A, Wilder E, Thorpe LE, Littman DR, Dittmann M, Stapleford KA, Shopsin B, Torres VJ, Ko AI, Iwasaki A, Cadwell K, Schluter J. Nat Commun. 2022 Nov 1; 2022 Nov 1. PMID: 36319618.
Trends in Precancerous Cervical Lesions by Area-Based Measures of Poverty, Race, and Ethnicity, Connecticut, 2008-2018.Brackney MM, Weinberger DM, Higgins K, Meek J, Niccolai LM. Public Health Rep. 2022 Nov-Dec; 2021 Nov 2. PMID: 34727517.
Predicted effectiveness of vaccines and extended half-life monoclonal antibodies against RSV hospitalizations in children.Zheng Z, Weinberger DM, Pitzer VE. NPJ Vaccines. 2022 Oct 27; 2022 Oct 27. PMID: 36302926.
Estimated incidence of respiratory hospitalizations attributable to RSV infections across age and socioeconomic groups.Zheng Z, Warren JL, Shapiro ED, Pitzer VE, Weinberger DM. Pneumonia (Nathan). 2022 Oct 25; 2022 Oct 25. PMID: 36280891.
Human neutrophil development and functionality are enabled in a humanized mouse model.Zheng Y, Sefik E, Astle J, Karatepe K, Öz HH, Solis AG, Jackson R, Luo HR, Bruscia EM, Halene S, Shan L, Flavell RA. Proc Natl Acad Sci U S A. 2022 Oct 25; 2022 Oct 21. PMID: 36269862.
Managing COVID-19 going forward-the lessons from history.Bucala R, Friedland G, Snowden FM. QJM. 2022 Oct 25. PMID: 35262710.
Developmental Transitions Coordinate Assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System.Park D, Steiner S, Shao M, Roy CR, Liu J. Infect Immun. 2022 Oct 20; 2022 Oct 3. PMID: 36190257.
LINE-1 activation in the cerebellum drives ataxia.Takahashi T, Stoiljkovic M, Song E, Gao XB, Yasumoto Y, Kudo E, Carvalho F, Kong Y, Park A, Shanabrough M, Szigeti-Buck K, Liu ZW, Kristant A, Zhang Y, Sulkowski P, Glazer PM, Kaczmarek LK, Horvath TL, Iwasaki A. Neuron. 2022 Oct 19; 2022 Sep 6. PMID: 36070749.
Bayesian Model Averaging to Account for Model Uncertainty in Estimates of a Vaccine's Effectiveness.Oliveira CR, Shapiro ED, Weinberger DM. Clin Epidemiol. 2022; 2022 Oct 18. PMID: 36281232.
MIF is a Common Genetic Determinant of COVID-19 Symptomatic Infection and Severity.Shin JJ, Fan W, Par-Young J, Piecychna M, Leng L, Israni-Winger K, Qing H, Gu J, Zhao H, Schulz WL, Unlu S, Kuster J, Young G, Liu J, Ko AI, Baeza Garcia A, Sauler M, Wisnewski AV, Young L, Orduña A, Wang A, Klementina O, Garcia AB, Hegyi P, Armstrong ME, Mitchell P, Ordiz DB, Garami A, Kang I, Bucala R. QJM. 2022 Oct 12; 2022 Oct 12. PMID: 36222594.
Macrophage Migration Inhibitory Factor (MIF) Promotes Increased Proportions of the Highly Permissive Th17-like Cell Profile during HIV Infection.Trifone C, Baquero L, Czernikier A, Benencio P, Leng L, Laufer N, Quiroga MF, Bucala R, Ghiglione Y, Turk G. Viruses. 2022 Oct 9; 2022 Oct 9. PMID: 36298774.
Trends in non-COVID-19 hospitalizations prior to and during the COVID-19 pandemic period, United States, 2017-2021.Cassell K, Zipfel CM, Bansal S, Weinberger DM. Nat Commun. 2022 Oct 8; 2022 Oct 8. PMID: 36209210.
In vivo correction of cystic fibrosis mediated by PNA nanoparticles.Piotrowski-Daspit AS, Barone C, Lin CY, Deng Y, Wu D, Binns TC, Xu E, Ricciardi AS, Putman R, Garrison A, Nguyen R, Gupta A, Fan R, Glazer PM, Saltzman WM, Egan ME. Sci Adv. 2022 Oct 7; 2022 Oct 5. PMID: 36197984.
Effectiveness of an inactivated Covid-19 vaccine with homologous and heterologous boosters against Omicron in Brazil.Ranzani OT, Hitchings MDT, de Melo RL, de França GVA, Fernandes CFR, Lind ML, Torres MSS, Tsuha DH, David LCS, Said RFC, Almiron M, de Oliveira RD, Cummings DAT, Dean NE, Andrews JR, Ko AI, Croda J. Nat Commun. 2022 Oct 6; 2022 Oct 6. PMID: 36202800.
Coronavirus Lung Infection Impairs Host Immunity against Secondary Bacterial Infection by Promoting Lysosomal Dysfunction.Peng X, Kim J, Gupta G, Agaronyan K, Mankowski MC, Korde A, Takyar SS, Shin HJ, Habet V, Voth S, Audia JP, Chang D, Liu X, Wang L, Cai Y, Tian X, Ishibe S, Kang MJ, Compton S, Wilen CB, Dela Cruz CS, Sharma L. J Immunol. 2022 Oct 1; 2022 Sep 2. PMID: 36165196.
Implementation of Pre-Admission Caregiver Testing for COVID-19.He M, Peaper DR, Murray T, Ciaburri R, Doyle J, Loyal J. Hosp Pediatr. 2022 Oct 1. PMID: 36047308.
Alterations in high-dimensional T-cell profile and gene signature of immune aging in HIV-infected older adults without viremia.Shin MS, Park HJ, Salahuddin S, Montgomery RR, Emu B, Shaw AC, Kang I. Aging Cell. 2022 Oct; 2022 Aug 29. PMID: 36036630.
Reemergence of Invasive Pneumococcal Disease in Germany During the Spring and Summer of 2021.Perniciaro S, van der Linden M, Weinberger DM. Clin Infect Dis. 2022 Sep 30. PMID: 35136983.
Gastrointestinal Microbiome Disruption and Antibiotic-Associated Diarrhea in Children Receiving Antibiotic Therapy for Community-Acquired Pneumonia.Kwon J, Kong Y, Wade M, Williams DJ, Creech CB, Evans S, Walter EB, Martin JM, Gerber JS, Newland JG, Hofto ME, Staat MA, Chambers HF, Fowler VG, Huskins WC, Pettigrew MM. J Infect Dis. 2022 Sep 21. PMID: 35249113.
Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung Injury.Harris ZM, Sun Y, Joerns J, Clark B, Hu B, Korde A, Sharma L, Shin HJ, Manning EP, Placek L, Unutmaz D, Stanley G, Chun H, Sauler M, Rajagopalan G, Zhang X, Kang MJ, Koff JL. Oxid Med Cell Longev. 2022; 2022 Sep 20. PMID: 36193076.
Linking rattiness, geography and environmental degradation to spillover Leptospira infections in marginalised urban settings: An eco-epidemiological community-based cohort study in Brazil.Eyre MT, Souza FN, Carvalho-Pereira TSA, Nery N, de Oliveira D, Cruz JS, Sacramento GA, Khalil H, Wunder EA, Hacker KP, Hagan JE, Childs JE, Reis MG, Begon M, Diggle PJ, Ko AI, Giorgi E, Costa F. Elife. 2022 Sep 16; 2022 Sep 16. PMID: 36111781.
The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging.Ryu S, Sidorov S, Ravussin E, Artyomov M, Iwasaki A, Wang A, Dixit VD. Immunity. 2022 Sep 13; 2022 Aug 12. PMID: 35963236.
Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer.Lee S, O'Donovan L, Cohen AJ, Gautam S, Quagliarello V, Juthani-Mehta M, Datta R. Antimicrob Steward Healthc Epidemiol. 2022; 2022 Sep 8. PMID: 36483405.
Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey.Fofana MO, Nery N Jr, Aguilar Ticona JP, de Andrade Belitardo EMM, Victoriano R, Anjos RO, Portilho MM, de Santana MC, Dos Santos LL, de Oliveira D, Cruz JS, Muenker MC, Khouri R, Wunder EA Jr, Hitchings MDT, Johnson O, Reis MG, Ribeiro GS, Cummings DAT, Costa F, Ko AI. PLoS Med. 2022 Sep; 2022 Sep 8. PMID: 36074784.
National Cohort Study of Homebound Persons Living With Dementia: Antibiotic Prescribing Trends and Opportunities for Antibiotic Stewardship.Datta R, Fried T, O'Leary JR, Zullo AR, Allore H, Han L, Juthani-Mehta M, Cohen A. Open Forum Infect Dis. 2022 Sep; 2022 Sep 3. PMID: 36147594.
Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults.Chou CH, Mohanty S, Kang HA, Kong L, Avila-Pacheco J, Joshi SR, Ueda I, Devine L, Raddassi K, Pierce K, Jeanfavre S, Bullock K, Meng H, Clish C, Santori FR, Shaw AC, Xavier RJ. Aging Cell. 2022 Sep; 2022 Aug 23. PMID: 35996998.
Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study.Ozonoff A, Schaenman J, Jayavelu ND, Milliren CE, Calfee CS, Cairns CB, Kraft M, Baden LR, Shaw AC, Krammer F, van Bakel H, Esserman DA, Liu S, Sesma AF, Simon V, Hafler DA, Montgomery RR, Kleinstein SH, Levy O, Bime C, Haddad EK, Erle DJ, Pulendran B, Nadeau KC, Davis MM, Hough CL, Messer WB, Higuita NIA, Metcalf JP, Atkinson MA, Brakenridge SC, Corry D, Kheradmand F, Ehrlich LIR, Melamed E, McComsey GA, Sekaly R, Diray-Arce J, Peters B, Augustine AD, Reed EF, Altman MC, Becker PM, Rouphael N. EBioMedicine. 2022 Sep; 2022 Aug 8. PMID: 35952496.
Reconstructing the course of the COVID-19 epidemic over 2020 for US states and counties: Results of a Bayesian evidence synthesis model.Chitwood MH, Russi M, Gunasekera K, Havumaki J, Klaassen F, Pitzer VE, Salomon JA, Swartwood NA, Warren JL, Weinberger DM, Cohen T, Menzies NA. PLoS Comput Biol. 2022 Aug; 2022 Aug 30. PMID: 36040963.
Decline in Pneumococcal Disease in Young Children During the Coronavirus Disease 2019 (COVID-19) Pandemic in Israel Associated With Suppression of Seasonal Respiratory Viruses, Despite Persistent Pneumococcal Carriage: A Prospective Cohort Study.Danino D, Ben-Shimol S, van der Beek BA, Givon-Lavi N, Avni YS, Greenberg D, Weinberger DM, Dagan R. Clin Infect Dis. 2022 Aug 24. PMID: 34904635.
Operation Nasal Vaccine-Lightning speed to counter COVID-19.Topol EJ, Iwasaki A. Sci Immunol. 2022 Aug 12; 2022 Aug 19. PMID: 35862488.
Author Correction: Unexplained post-acute infection syndromes.Choutka J, Jansari V, Hornig M, Iwasaki A. Nat Med. 2022 Aug. PMID: 35859204.
"Near Cure" treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct.Vandenbark AA, Meza-Romero R, Wiedrick J, Gerstner G, Seifert H, Kent G, Piechycna M, Benedek G, Bucala R, Offner H. Cell Immunol. 2022 Aug; 2022 Jun 11. PMID: 35738135.
Defining Clinical and Immunological Predictors of Poor Immune Responses to COVID-19 mRNA Vaccines in Patients with Primary Antibody Deficiency.Shin JJ, Par-Young J, Unlu S, McNamara A, Park HJ, Shin MS, Gee RJ, Doyle H, Afinogenova Y, Zidan E, Kwah J, Russo A, Mamula M, Hsu FI, Catanzaro J, Racke M, Bucala R, Wilen C, Kang I. J Clin Immunol. 2022 Aug; 2022 Jun 17. PMID: 35713752.
Real-world assessment of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) nasopharyngeal swab testing in a region with a high burden of coronavirus disease 2019 (COVID-19).Sangal RB, Peaper DR, Rothenberg C, Fadlallah H, Mobolaji-Lawal M, Landry ML, Sussman LS, Ulrich A, Venkatesh AK. Infect Control Hosp Epidemiol. 2022 Aug; 2021 Apr 7. PMID: 33823949.
Evaluation of the impact of chemical control on the ecology of Rattus norvegicus of an urban community in Salvador, Brazil.Pertile AC, Lustosa R, Carvalho-Pereira T, Pedra GG, Panti-May JA, Oliveira U, Zeppelini CG, Souza FN, Oliveira DS, Khalil H, Reis MG, Childs J, Ko AI, Begon M, Costa F. PLoS One. 2022; 2022 Jul 20. PMID: 35857771.
Development of an efficient reproducible cell-cell transmission assay for rapid quantification of SARS-CoV-2 spike interaction with hACE2.Ssenyange G, Kerfoot M, Zhao M, Farhadian S, Chen S, Peng L, Ren P, Dela Cruz CS, Gupta S, Sutton RE. Cell Rep Methods. 2022 Jul 18; 2022 Jun 20. PMID: 35757815.
Emerging Concepts in Defective Macrophage Phagocytosis in Cystic Fibrosis.Jaganathan D, Bruscia EM, Kopp BT. Int J Mol Sci. 2022 Jul 13; 2022 Jul 13. PMID: 35887098.
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation.Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, O'Dea MR, Dutton S, Shamardani K, Nwangwu K, Mancusi R, Yalçın B, Taylor KR, Acosta-Alvarez L, Malacon K, Keough MB, Ni L, Woo PJ, Contreras-Esquivel D, Toland AMS, Gehlhausen JR, Klein J, Takahashi T, Silva J, Israelow B, Lucas C, Mao T, Peña-Hernández MA, Tabachnikova A, Homer RJ, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Vogel H, Hefti MM, Perl DP, Liddelow S, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M. Cell. 2022 Jul 7; 2022 Jun 13. PMID: 35768006.