CPIRT Publications

2023

Structural insights into the career path between pre- and postgraduate physician-scientist training programs.Williams CS, Gallagher EJ, Rockey DC, Ajijola OA, Hu PJ, Kazmierczak BI, Kontos CD, Vyas JM, Zaidi M, Rhee KY. Elife. 2023 Oct 2; 2023 Oct 2. PMID: 37782020.
Rescue of alveolar wall liquid secretion blocks fatal lung injury due to influenza-staphylococcal coinfection.Tang S, De Jesus AC, Chavez D, Suthakaran S, Moore SK, Suthakaran K, Homami S, Rathnasinghe R, May AJ, Schotsaert M, Britto CJ, Bhattacharya J, Hook JL. J Clin Invest. 2023 Oct 2; 2023 Oct 2. PMID: 37581936.
Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC).Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. Nat Immunol. 2023 Oct. PMID: 37723351.
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC).Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. Nat Immunol. 2023 Oct; 2023 Sep 4. PMID: 37667052.
Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) RNA and viable virus contamination of hospital emergency department surfaces and association with patient coronavirus disease 2019 (COVID-19) status and aerosol-generating procedures.Roberts SC, Barbell ES, Barber D, Dahlberg SE, Heimer R, Jubanyik K, Parwani V, Pettigrew MM, Tanner JM, Ulrich A, Wade M, Wyllie AL, Yolda-Carr D, Martinello RA, Tanner WD. Infect Control Hosp Epidemiol. 2023 Sep 28; 2023 Sep 28. PMID: 37767709.
Distinguishing features of Long COVID identified through immune profiling.Klein J, Wood J, Jaycox J, Dhodapkar RM, Lu P, Gehlhausen JR, Tabachnikova A, Greene K, Tabacof L, Malik AA, Silva Monteiro V, Silva J, Kamath K, Zhang M, Dhal A, Ott IM, Valle G, Peña-Hernandez M, Mao T, Bhattacharjee B, Takahashi T, Lucas C, Song E, Mccarthy D, Breyman E, Tosto-Mancuso J, Dai Y, Perotti E, Akduman K, Tzeng TJ, Xu L, Geraghty AC, Monje M, Yildirim I, Shon J, Medzhitov R, Lutchmansingh D, Possick JD, Kaminski N, Omer SB, Krumholz HM, Guan L, Dela Cruz CS, van Dijk D, Ring AM, Putrino D, Iwasaki A. Nature. 2023 Sep 25; 2023 Sep 25. PMID: 37748514.
Threatening the Future of Global Health - NIH Policy Changes on International Research Collaborations.Ko AI, Abdool Karim SS, Morel C, Swaminathan S, Daszak P, Keusch GT. N Engl J Med. 2023 Sep 7; 2023 Sep 2. PMID: 37668223.
Immunology for the Rheumatologist: A&R introduces a new problem-based immunology review series with great educational potential.Bucala R, Solomon DH. Arthritis Rheumatol. 2023 Sep 1; 2023 Sep 1. PMID: 37655656.
The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study.Kim JY, Jung JW, Kang MJ, Kim DK, Choi H, Cho YJ, Jang SH, Lee CH, Oh YM, Park JS. Korean J Intern Med. 2023 Sep; 2023 Aug 17. PMID: 37586811.
Pyroptosis in cardiovascular diseases: Pumping gasdermin on the fire.Yarovinsky TO, Su M, Chen C, Xiang Y, Tang WH, Hwa J. Semin Immunol. 2023 Sep; 2023 Jul 19. PMID: 37478801.
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model.Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan WY, Davidson EA, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder EA, Coppi A, Schulz W, Iwasaki A, Pierce RW, Cruz CSD, Desir GV, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis NS, Ko AI, Thompson DC, Vasiliou V. Hum Genomics. 2023 Aug 29; 2023 Aug 29. PMID: 37641126.
Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.Pekayvaz K, Gold C, Hoseinpour P, Engel A, Martinez-Navarro A, Eivers L, Coletti R, Joppich M, Dionísio F, Kaiser R, Tomas L, Janjic A, Knott M, Mehari F, Polewka V, Kirschner M, Boda A, Nicolai L, Schulz H, Titova A, Kilani B, Lorenz M, Fingerle-Rowson G, Bucala R, Enard W, Zimmer R, Weber C, Libby P, Schulz C, Massberg S, Stark K. Immunity. 2023 Aug 24; 2023 Aug 24. PMID: 37652021.
Prior cycles of anti-CD20 antibodies affect antibody responses after repeated SARS-CoV-2 mRNA vaccination.Asashima H, Kim D, Wang K, Lele N, Buitrago-Pocasangre NC, Lutz R, Cruz I, Raddassi K, Ruff WE, Racke MK, Wilson JE, Givens TS, Grifoni A, Weiskopf D, Sette A, Kleinstein SH, Montgomery RR, Shaw AC, Li F, Fan R, Hafler DA, Tomayko MM, Longbrake EE. JCI Insight. 2023 Aug 22; 2023 Aug 22. PMID: 37606046.
Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging.Kumar A, Wang J, Esterly A, Radcliffe C, Zhou H, Wyk BV, Allore HG, Tsang S, Barakat L, Mohanty S, Zhao H, Shaw AC, Zapata HJ. Aging (Albany NY). 2023 Aug 21; 2023 Aug 21. PMID: 37606991.
Evidence of leaky protection following COVID-19 vaccination and SARS-CoV-2 infection in an incarcerated population.Lind ML, Dorion M, Houde AJ, Lansing M, Lapidus S, Thomas R, Yildirim I, Omer SB, Schulz WL, Andrews JR, Hitchings MDT, Kennedy BS, Richeson RP, Cummings DAT, Ko AI. Nat Commun. 2023 Aug 19; 2023 Aug 19. PMID: 37598213.
Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination.Suberi A, Grun MK, Mao T, Israelow B, Reschke M, Grundler J, Akhtar L, Lee T, Shin K, Piotrowski-Daspit AS, Homer RJ, Iwasaki A, Suh HW, Saltzman WM. Sci Transl Med. 2023 Aug 16; 2023 Aug 16. PMID: 37585505.
Zika virus RNA persistence and recovery in water and wastewater: An approach for Zika virus surveillance in resource-constrained settings.Zhu K, Hill C, Muirhead A, Basu M, Brown J, Brinton MA, Hayat MJ, Venegas-Vargas C, Reis MG, Casanovas-Massana A, Meschke JS, Ko AI, Costa F, Stauber CE. Water Res. 2023 Aug 1; 2023 May 23. PMID: 37270953.
A Multiclass Radiomics Method-Based WHO Severity Scale for Improving COVID-19 Patient Assessment and Disease Characterization From CT Scans.Henao JAG, Depotter A, Bower DV, Bajercius H, Todorova PT, Saint-James H, de Mortanges AP, Barroso MC, He J, Yang J, You C, Staib LH, Gange C, Ledda RE, Caminiti C, Silva M, Cortopassi IO, Dela Cruz CS, Hautz W, Bonel HM, Sverzellati N, Duncan JS, Reyes M, Poellinger A. Invest Radiol. 2023 Jul 27; 2023 Jul 27. PMID: 37493348.
IL-7R licenses a population of epigenetically poised memory CD8(+) T cells with superior antitumor efficacy that are critical for melanoma memory.Micevic G, Daniels A, Flem-Karlsen K, Park K, Talty R, McGeary M, Mirza H, Blackburn HN, Sefik E, Cheung JF, Hornick NI, Aizenbud L, Joshi NS, Kluger H, Iwasaki A, Bosenberg MW, Flavell RA. Proc Natl Acad Sci U S A. 2023 Jul 25; 2023 Jul 17. PMID: 37459511.
COVID-19 annual update: a narrative review.Biancolella M, Colona VL, Luzzatto L, Watt JL, Mattiuz G, Conticello SG, Kaminski N, Mehrian-Shai R, Ko AI, Gonsalves GS, Vasiliou V, Novelli G, Reichardt JKV. Hum Genomics. 2023 Jul 24; 2023 Jul 24. PMID: 37488607.
MPL36, a major plasminogen (PLG) receptor in pathogenic Leptospira, has an essential role during infection.Zhu W, Passalia FJ, Hamond C, Abe CM, Ko AI, Barbosa AS, Wunder EA Jr. PLoS Pathog. 2023 Jul; 2023 Jul 24. PMID: 37486929.
Year-round RSV Transmission in the Netherlands Following the COVID-19 Pandemic - A Prospective Nationwide Observational and Modeling Study.Löwensteyn YN, Zheng Z, Rave N, Bannier MAGE, Billard MN, Casalegno JS, Pitzer VE, Wildenbeest JG, Weinberger DM, Bont L. J Infect Dis. 2023 Jul 21; 2023 Jul 21. PMID: 37477906.
Failure to Detect Influenza A H1N1 Highlights the Need for Multiple Gene Targets in Influenza Molecular Tests.Landry ML, Owen M. J Clin Microbiol. 2023 Jul 20; 2023 Jun 20. PMID: 37338345.
Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer.Huth S, Huth L, Heise R, Marquardt Y, Lopopolo L, Piecychna M, Boor P, Fingerle-Rowson G, Kapurniotu A, Yazdi AS, Bucala R, Bernhagen J, Baron JM. Sci Rep. 2023 Jul 18; 2023 Jul 18. PMID: 37464010.
The MIF promoter SNP rs755622 is associated with immune activation in glioblastoma.Alban TJ, Grabowski MM, Otvos B, Bayik D, Wang W, Zalavadia A, Makarov V, Troike K, McGraw M, Rabljenovic A, Lauko A, Neumann C, Roversi G, Waite KA, Cioffi G, Patil N, Tran TT, McCortney K, Steffens A, Diaz CM, Brown JM, Egan KM, Horbinski CM, Barnholtz-Sloan JS, Rajappa P, Vogelbaum MA, Bucala R, Chan TA, Ahluwalia MS, Lathia JD. JCI Insight. 2023 Jul 10; 2023 Jul 10. PMID: 37252795.
PROSER: A Web-Based Peripheral Blood Smear Interpretation Support Tool Utilizing Electronic Health Record Data.Iscoe MS, Loza AJ, Turbiville D, Campbell SM, Peaper DR, Balbuena-Merle RI, Hauser RG. Am J Clin Pathol. 2023 Jul 5. PMID: 37026746.
VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis.Kim SH, Adams TS, Hu Q, Shin HJ, Chae G, Lee SE, Sharma L, Kwon HK, Lee FY, Park HJ, Huh WJ, Manning E, Kaminski N, Sauler M, Chen L, Song JW, Kim TK, Kang MJ. Am J Respir Cell Mol Biol. 2023 Jul. PMID: 36450109.
Advances in molecular infectious diseases testing in the time of COVID-19.Peaper DR, Kerantzas CA, Durant TJS. Clin Biochem. 2023 Jul; 2022 Feb 15. PMID: 35181291.
Increasing sensitivity of antibody-antigen interactions using photo-cross-linking.Torrents de la Peña A, Sewall LM, de Paiva Froes Rocha R, Jackson AM, Pratap PP, Bangaru S, Cottrell CA, Mohanty S, Shaw AC, Ward AB. Cell Rep Methods. 2023 Jun 26; 2023 Jun 5. PMID: 37426749.
High-throughput single-cell profiling of B cell responses following inactivated influenza vaccination in young and older adults.Wang M, Jiang R, Mohanty S, Meng H, Shaw AC, Kleinstein SH. Aging (Albany NY). 2023 Jun 26; 2023 Jun 26. PMID: 37367734.
Genomic analysis of plasma circulating tumor DNA in patients with heavily pretreated HER2 + metastatic breast cancer.Lee K, Lee J, Choi J, Sim SH, Kim JE, Kim MH, Park YH, Kim JH, Koh SJ, Park KH, Kang MJ, Ahn MS, Lee KE, Kim HJ, Ahn HK, Kim HJ, Park KU, Park IH. Sci Rep. 2023 Jun 19; 2023 Jun 19. PMID: 37336919.
A pref-1-controlled non-inflammatory mechanism of insulin resistance.Huang Y, Cui D, Chen L, Tong H, Wu H, Muller GK, Qi Y, Wang S, Xu J, Gao X, Fifield KE, Wang L, Xia Z, Vanderluit JL, Liu S, Leng L, Sun G, McGuire J, Young LH, Bucala R, Qi D. iScience. 2023 Jun 16; 2023 May 19. PMID: 37283810.
High Levels of Detection of Nonpneumococcal Species of Streptococcus in Saliva from Adults in the United States.Hislop MS, Allicock OM, Thammavongsa DA, Mbodj S, Nelson A, Shaw AC, Weinberger DM, Wyllie AL. Microbiol Spectr. 2023 Jun 15; 2023 Apr 17. PMID: 37067447.
Persistence of Pneumococcal Carriage among Older Adults in the Community despite COVID-19 Mitigation Measures.Wyllie AL, Mbodj S, Thammavongsa DA, Hislop MS, Yolda-Carr D, Waghela P, Nakahata M, Stahlfeld AE, Vega NJ, York A, Allicock OM, Wilkins G, Ouyang A, Siqueiros L, Strong Y, Anastasio K, Alexander-Parrish R, Arguedas A, Gessner BD, Weinberger DM. Microbiol Spectr. 2023 Jun 15; 2023 Apr 10. PMID: 37036377.
The Impact of Coronavirus Disease 2019 on Viral, Bacterial, and Fungal Respiratory Infections.Losier A, Gupta G, Caldararo M, Dela Cruz CS. Clin Chest Med. 2023 Jun; 2023 Feb 26. PMID: 37085229.
Immunomodulatory Agents for Coronavirus Disease-2019 Pneumonia.McManus D, Davis MW, Ortiz A, Britto-Leon C, Dela Cruz CS, Topal JE. Clin Chest Med. 2023 Jun; 2022 Nov 22. PMID: 37085221.
Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain.Ye S, Mahmood DFD, Ma F, Leng L, Bucala R, Vera PL. Cells. 2023 May 22; 2023 May 22. PMID: 37408274.
Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine-associated myocarditis.Barmada A, Klein J, Ramaswamy A, Brodsky NN, Jaycox JR, Sheikha H, Jones KM, Habet V, Campbell M, Sumida TS, Kontorovich A, Bogunovic D, Oliveira CR, Steele J, Hall EK, Pena-Hernandez M, Monteiro V, Lucas C, Ring AM, Omer SB, Iwasaki A, Yildirim I, Lucas CL. Sci Immunol. 2023 May 12; 2023 May 5. PMID: 37146127.
The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire Properties.Jiang R, Roy B, Wu Q, Mohanty S, Nowak RJ, Shaw AC, Kleinstein SH, O'Connor KC. Immunohorizons. 2023 May 1. PMID: 37171806.
Excess Mortality Among Patients in the Veterans Affairs Health System Compared With the Overall US Population During the First Year of the COVID-19 Pandemic.Weinberger DM, Rose L, Rentsch C, Asch SM, Columbo JA, King J Jr, Korves C, Lucas BP, Taub C, Young-Xu Y, Vashi A, Davies L, Justice AC. JAMA Netw Open. 2023 May 1; 2023 May 1. PMID: 37155169.
Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study.Datta R, Han L, Doyle M, Allore H, Sanft T, Quagliarello V, Juthani-Mehta M. Palliat Med. 2023 May; 2023 Mar 31. PMID: 36999898.
Molecular Characterization of Leptospira Species Detected in the Kidneys of Slaughtered Livestock in Abattoirs in Gauteng Province, South Africa.Dogonyaro BB, van Heerden H, Potts AD, Fasina FO, Casanovas-Massana A, Kolo FB, Lötter C, Byaruhanga C, Ko AI, Wunder EA Jr, Adesiyun AA. Pathogens. 2023 Apr 30; 2023 Apr 30. PMID: 37242336.
Adaptation of Nontypeable Haemophilus influenzae in Human Airways in COPD: Genome Rearrangements and Modulation of Expression of HMW1 and HMW2.Murphy TF, Kirkham C, D'Mello A, Sethi S, Pettigrew MM, Tettelin H. mBio. 2023 Apr 25; 2023 Mar 16. PMID: 36927061.
Identification of Efflux Substrates Using a Riboswitch-Based Reporter in Pseudomonas aeruginosa.Urdaneta-Páez V, Hamchand R, Anthony K, Crawford J, Sutherland AG, Kazmierczak BI. mSphere. 2023 Apr 20; 2023 Mar 22. PMID: 36946743.
Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants.Moriyama M, Lucas C, Monteiro VS, Iwasaki A. Proc Natl Acad Sci U S A. 2023 Apr 18; 2023 Apr 10. PMID: 37036977.
Type 2 Dendritic Cells Orchestrate a Local Immune Circuit to Confer Antimetastatic Immunity.Weizman OE, Luyten S, Krykbaeva I, Song E, Mao T, Bosenberg M, Iwasaki A. J Immunol. 2023 Apr 15. PMID: 36881866.
A Novel Zinc (II) Porphyrin Is Synergistic with PEV2 Bacteriophage against Pseudomonas aeruginosa Infections.Geyer J, Krupa KA, Harris ZM, Sun Y, Sharma L, Würstle S, Hu B, Stanley G, Rajagopalan G, Pellot E, Koff JL, Robinson JB. Antibiotics (Basel). 2023 Apr 10; 2023 Apr 10. PMID: 37107097.
Nonsystematic Reporting Biases of the SARS-CoV-2 Variant Mu Could Impact Our Understanding of the Epidemiological Dynamics of Emerging Variants.Petrone ME, Lucas C, Menasche B, Breban MI, Yildirim I, Campbell M, Omer SB, Holmes EC, Ko AI, Grubaugh ND, Iwasaki A, Wilen CB, Vogels CBF, Fauver JR. Genome Biol Evol. 2023 Apr 5. PMID: 36974986.
The effects of elexafactor/tezafactor/ivacaftor beyond the epithelium: spurring macrophages to fight infections.Bruscia EM. Eur Respir J. 2023 Apr; 2023 Apr 1. PMID: 37003613.
Why we need a deeper understanding of the pathophysiology of long COVID.Iwasaki A, Putrino D. Lancet Infect Dis. 2023 Apr; 2023 Feb 14. PMID: 36967698.
The COVID-19 pandemic as an opportunity for unravelling the causative association between respiratory viruses and pneumococcus-associated disease in young children: a prospective study.Dagan R, van der Beek BA, Ben-Shimol S, Greenberg D, Shemer-Avni Y, Weinberger DM, Danino D. EBioMedicine. 2023 Apr; 2023 Feb 28. PMID: 36857965.
Coronaviruses, Lysosomes, and Secondary Bacterial Infections: Coronaviruses Outsmart the Host.Peng X, Dela Cruz CS, Sharma L. DNA Cell Biol. 2023 Apr; 2023 Feb 10. PMID: 36763591.
Mature B cells and mesenchymal stem cells control emergency myelopoiesis.Lim VY, Feng X, Miao R, Zehentmeier S, Ewing-Crystal N, Lee M, Tumanov AV, Oh JE, Iwasaki A, Wang A, Choi J, Pereira JP. Life Sci Alliance. 2023 Apr; 2023 Jan 30. PMID: 36717247.
MIF is a common genetic determinant of COVID-19 symptomatic infection and severity.Shin JJ, Fan W, Par-Young J, Piecychna M, Leng L, Israni-Winger K, Qing H, Gu J, Zhao H, Schulz WL, Unlu S, Kuster J, Young G, Liu J, Ko AI, Baeza Garcia A, Sauler M, Wisnewski AV, Young L, Orduña A, Wang A, Ocskay K, Garcia-Blesa A, Hegyi P, Armstrong ME, Mitchell PD, Bernardo D, Garami A, Kang I, Bucala R. QJM. 2023 Mar 27. PMID: 36222594.
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms.Taghi Khani A, Kumar A, Sanchez Ortiz A, Radecki KC, Aramburo S, Lee SJ, Hu Z, Damirchi B, Lorenson MY, Wu X, Gu Z, Stohl W, Sanz I, Meffre E, Müschen M, Forman SJ, Koff JL, Walker AM, Swaminathan S. Commun Biol. 2023 Mar 20; 2023 Mar 20. PMID: 36941341.
The Coxiella burnetii effector EmcB is a deubiquitinase that inhibits RIG-I signaling.Duncan-Lowey J, Crabill E, Jarret A, Reed SCO, Roy CR. Proc Natl Acad Sci U S A. 2023 Mar 14; 2023 Mar 9. PMID: 36893270.
Covid-19 vaccine acceptance among individuals incarcerated in Connecticut state jails.Lind ML, Kennedy BS, Nieto MD, Houde AJ, Sosensky P, Borg R, Cummings DAT, Ko AI, Richeson RP. Health Justice. 2023 Mar 13; 2023 Mar 13. PMID: 36913159.
SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity.Jaycox JR, Lucas C, Yildirim I, Dai Y, Wang EY, Monteiro V, Lord S, Carlin J, Kita M, Buckner JH, Ma S, Campbell M, Ko A, Omer S, Lucas CL, Speake C, Iwasaki A, Ring AM. Nat Commun. 2023 Mar 9; 2023 Mar 9. PMID: 36894554.
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection.Wei J, Patil A, Collings CK, Alfajaro MM, Liang Y, Cai WL, Strine MS, Filler RB, DeWeirdt PC, Hanna RE, Menasche BL, Ökten A, Peña-Hernández MA, Klein J, McNamara A, Rosales R, McGovern BL, Luis Rodriguez M, García-Sastre A, White KM, Qin Y, Doench JG, Yan Q, Iwasaki A, Zwaka TP, Qi J, Kadoch C, Wilen CB. Nat Genet. 2023 Mar; 2023 Mar 9. PMID: 36894709.
Response to: Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect.Takahashi T, Stoiljkovic M, Song E, Gao XB, Yasumoto Y, Kudo E, Carvalho F, Kong Y, Park A, Shanabrough M, Szigeti-Buck K, Liu ZW, Kristant A, Zhang Y, Sulkowski P, Glazer PM, Kaczmarek LK, Horvath TL, Iwasaki A. Neuron. 2023 Mar 1. PMID: 36863323.
NLRX1 knockdown attenuates pro-apoptotic signaling and cell death in pulmonary hyperoxic acute injury.Kim HR, Kim MN, Kim EG, Leem JS, Baek SM, Lee YJ, Kim KW, Kang MJ, Song TW, Sohn MH. Sci Rep. 2023 Mar 1; 2023 Mar 1. PMID: 36859435.
Use of Whole-Genome Sequencing to Estimate the Contribution of Immune Evasion and Waning Immunity on Decreasing COVID-19 Vaccine Effectiveness.Lind ML, Copin R, McCarthy S, Coppi A, Warner F, Ferguson D, Duckwall C, Borg R, Muenker MC, Overton J, Hamon S, Zhou A, Cummings DAT, Ko AI, Hamilton JD, Schulz WL, Hitchings MDT. J Infect Dis. 2023 Mar 1. PMID: 36408616.
Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection.Ganesan S, Alvarez NN, Steiner S, Fowler KM, Corona AK, Roy CR. mBio. 2023 Feb 28; 2023 Feb 2. PMID: 36728431.
Magnetic bead-based separation of pneumococcal serotypes.York A, Huynh E, Mbodj S, Yolda-Carr D, Hislop MS, Echlin H, Rosch JW, Weinberger DM, Wyllie AL. Cell Rep Methods. 2023 Feb 27; 2023 Feb 21. PMID: 36936076.
Direct and indirect mortality impacts of the COVID-19 pandemic in the United States, March 1, 2020 to January 1, 2022.Lee WE, Woo Park S, Weinberger DM, Olson D, Simonsen L, Grenfell BT, Viboud C. Elife. 2023 Feb 22; 2023 Feb 22. PMID: 36811598.
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.Ahangari F, Price NL, Malik S, Chioccioli M, Bärnthaler T, Adams TS, Kim J, Pradeep SP, Ding S, Cosmos C Jr, Rose KS, McDonough JE, Aurelien NR, Ibarra G, Omote N, Schupp JC, DeIuliis G, Villalba Nunez JA, Sharma L, Ryu C, Dela Cruz CS, Liu X, Prasse A, Rosas I, Bahal R, Fernández-Hernando C, Kaminski N. JCI Insight. 2023 Feb 22; 2023 Feb 22. PMID: 36626225.
Age-dependent impairment in antibody responses elicited by a homologous CoronaVac booster dose.Filardi BA, Monteiro VS, Schwartzmann PV, do Prado Martins V, Zucca LER, Baiocchi GC, Malik AA, Silva J, Hahn AM, Chen NFG, Pham K, Pérez-Then E, Miric M, Brache V, Cochon L, Larocca RA, Mendez RDR, Bardini Silveira D, Pinto AR, Croda J, Yildirim I, Omer SB, Ko AI, Vermund SH, Grubaugh ND, Iwasaki A, Lucas C, Vogels CBF, Breban M, Koch TR, Chaguza C, Tikhonova I, Castaldi C, Mane S, De Kumar B, Ferguson D, Kerantzas N, Peaper D, Landry ML, Schulz W. Sci Transl Med. 2023 Feb 15; 2023 Feb 15. PMID: 36791210.
Nonutility of procalcitonin for diagnosing bacterial pneumonia in patients with severe COVID-19.Cohen AJ, Glick LR, Lee S, Kunitomo Y, Tsang DA, Pitafi S, Valda Toro P, Ristic NR, Zhang E, Carey GB, Datta R, Dela Cruz CS, Gautam S. Eur Clin Respir J. 2023; 2023 Feb 8. PMID: 36815942.
Testing Frequency Matters: An Evaluation of the Diagnostic Performance of a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Rapid Antigen Test in US Correctional Facilities.Lind ML, Schultes OL, Robertson AJ, Houde AJ, Cummings DAT, Ko AI, Kennedy BS, Richeson RP. Clin Infect Dis. 2023 Feb 8. PMID: 35686341.
Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti-PD-1 Immunotherapy in Endometrial Carcinoma.Chow RD, Michaels T, Bellone S, Hartwich TMP, Bonazzoli E, Iwasaki A, Song E, Santin AD. Cancer Discov. 2023 Feb 6. PMID: 36301137.
Routine saliva testing for SARS-CoV-2 in children: Methods for partnering with community childcare centers.Rayack EJ, Askari HM, Zirinsky E, Lapidus S, Sheikha H, Peno C, Kazemi Y, Yolda-Carr D, Liu C, Grubaugh ND, Ko AI, Wyllie AL, Spatz ES, Oliveira CR, Bei AK. Front Public Health. 2023; 2023 Feb 3. PMID: 36817891.
Platelet response to influenza vaccination reflects effects of aging.Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins TP, Belshe RB, Chawla DG, Rondina MT, Gill TM, Montgomery RR, Allore HG, Kleinstein SH, Shaw AC. Aging Cell. 2023 Feb; 2023 Jan 19. PMID: 36656789.
Glucocorticoid Therapy in COVID-19.Amati F, Tonutti A, Huston J, Dela Cruz CS. Semin Respir Crit Care Med. 2023 Feb; 2023 Jan 16. PMID: 36646089.
COVID-19.Dela Cruz CS, Feldman C. Semin Respir Crit Care Med. 2023 Feb; 2023 Jan 16. PMID: 36646080.
Correction to: Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb. PMID: 36565380.
Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb; 2022 Nov 19. PMID: 36401063.
PD-1(high)CXCR5(-)CD4(+) peripheral helper T cells promote CXCR3(+) plasmablasts in human acute viral infection.Asashima H, Mohanty S, Comi M, Ruff WE, Hoehn KB, Wong P, Klein J, Lucas C, Cohen I, Coffey S, Lele N, Greta L, Raddassi K, Chaudhary O, Unterman A, Emu B, Kleinstein SH, Montgomery RR, Iwasaki A, Dela Cruz CS, Kaminski N, Shaw AC, Hafler DA, Sumida TS. Cell Rep. 2023 Jan 31; 2023 Jan 2. PMID: 36596303.
Identification of two specific transcriptomic clusters of COVID-19 acute respiratory distress syndrome patients with different immune profiles and different outcomes.Shindo Y, Dela Cruz CS, Witzenrath M. Eur Respir J. 2023 Jan; 2023 Jan 27. PMID: 36517181.
COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation.Patton MJ, Orihuela CJ, Harrod KS, Bhuiyan MAN, Dominic P, Kevil CG, Fort D, Liu VX, Farhat M, Koff JL, Lal CV, Gaggar A, Richter RP, Erdmann N, Might M, Gaggar A. Crit Care. 2023 Jan 23; 2023 Jan 23. PMID: 36691080.
Editorial: Thematic issue on bacterial-viral co-infections.Manna S, Weinberger DM, Satzke C. FEMS Microbes. 2023; 2023 Jan 19. PMID: 37333434.
Waning Effectiveness of the BNT162b2 Vaccine Against Infection in Adolescents in Israel.Prunas O, Weinberger DM, Pitzer VE, Gazit S, Patalon T. Clin Infect Dis. 2023 Jan 6. PMID: 36484301.
Choice Architecture to Assist Clinicians with Appropriate COVID-19 Test Ordering.Sangal RB, Venkatesh AK, Cahill J, Pettker CM, Peaper DR. J Appl Lab Med. 2023 Jan 4. PMID: 36610419.
Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells.Tyagi T, Jain K, Yarovinsky TO, Chiorazzi M, Du J, Castro C, Griffin J, Korde A, Martin KA, Takyar SS, Flavell RA, Patel AA, Hwa J. J Exp Med. 2023 Jan 2; 2022 Oct 28. PMID: 36305874.
Bacteriophage Therapy for Pan-Drug-Resistant Pseudomonas aeruginosa in Two Persons With Cystic Fibrosis.Hahn A, Sami I, Chaney H, Koumbourlis AC, Del Valle Mojica C, Cochrane C, Chan BK, Koff JL. J Investig Med High Impact Case Rep. 2023 Jan-Dec. PMID: 37515541.
Reflections for the 50th Anniversary of The Journal of Rheumatology: The Past, Present, and Future of Rheumatology.Masi AT, Bucala RJ. J Rheumatol. 2023 Jan. PMID: 36587952.
Nasal host response-based screening for undiagnosed respiratory viruses: a pathogen surveillance and detection study.Cheemarla NR, Hanron A, Fauver JR, Bishai J, Watkins TA, Brito AF, Zhao D, Alpert T, Vogels CBF, Ko AI, Schulz WL, Landry ML, Grubaugh ND, van Dijk D, Foxman EF. Lancet Microbe. 2023 Jan. PMID: 36586415.
IFN-γ Is Protective in Cytokine Release Syndrome-associated Extrapulmonary Acute Lung Injury.Sun Y, Hu B, Stanley G, Harris ZM, Gautam S, Homer R, Koff JL, Rajagopalan G. Am J Respir Cell Mol Biol. 2023 Jan. PMID: 36125351.
Adding Insult to Injury: Does COVID-19 Promote Acute Respiratory Distress Syndrome by Inhibiting Surfactant?Richmond BW, Dela Cruz CS. Am J Respir Crit Care Med. 2023 Jan 1. PMID: 35976979.

2022

Inhaled Bacteriophage Therapy for Multi-Drug Resistant Achromobacter.Winzig F, Gandhi S, Lee A, Würstle S, Stanley GL, Capuano I, Neuringer I, Koff JL, Turner PE, Chan BK. Yale J Biol Med. 2022 Dec; 2022 Dec 22. PMID: 36568830.
Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein.Lapidus S, Liu F, Casanovas-Massana A, Dai Y, Huck JD, Lucas C, Klein J, Filler RB, Strine MS, Sy M, Deme AB, Badiane AS, Dieye B, Ndiaye IM, Diedhiou Y, Mbaye AM, Diagne CT, Vigan-Womas I, Mbengue A, Sadio BD, Diagne MM, Moore AJ, Mangou K, Diallo F, Sene SD, Pouye MN, Faye R, Diouf B, Nery N Jr, Costa F, Reis MG, Muenker MC, Hodson DZ, Mbarga Y, Katz BZ, Andrews JR, Campbell M, Srivathsan A, Kamath K, Baum-Jones E, Faye O, Sall AA, Vélez JCQ, Cappello M, Wilson M, Ben-Mamoun C, Tedder R, McClure M, Cherepanov P, Somé FA, Dabiré RK, Moukoko CEE, Ouédraogo JB, Boum Y 2nd, Shon J, Ndiaye D, Wisnewski A, Parikh S, Iwasaki A, Wilen CB, Ko AI, Ring AM, Bei AK. Sci Rep. 2022 Dec 22; 2022 Dec 22. PMID: 36550362.
Impact of Temporary Storage Conditions on the Viability of Streptococcus pneumoniae in Saliva.Allicock OM, York A, Waghela P, Yolda-Carr D, Weinberger DM, Wyllie AL. mSphere. 2022 Dec 21; 2022 Nov 21. PMID: 36409104.
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Am J Respir Crit Care Med. 2022 Dec 15. PMID: 35998281.
Leptospira Infection in Rural Areas of Urabá Region, Colombia: A Prospective Study.Quintero-Vélez JC, Rodas JD, Rojas CA, Ko AI, Wunder EA. Am J Trop Med Hyg. 2022 Dec 14; 2022 Nov 14. PMID: 36375452.
Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis.Öz HH, Cheng EC, Di Pietro C, Tebaldi T, Biancon G, Zeiss C, Zhang PX, Huang PH, Esquibies SS, Britto CJ, Schupp JC, Murray TS, Halene S, Krause DS, Egan ME, Bruscia EM. Cell Rep. 2022 Dec 13. PMID: 36516754.
Why is leptospirosis hard to avoid for the impoverished? Deconstructing leptospirosis transmission risk and the drivers of knowledge, attitudes, and practices in a disadvantaged community in Salvador, Brazil.Palma FAG, Costa F, Lustosa R, Mogaji HO, de Oliveira DS, Souza FN, Reis MG, Ko AI, Begon M, Khalil H. PLOS Glob Public Health. 2022; 2022 Dec 9. PMID: 36962720.
Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case-control analysis.Lind ML, Robertson AJ, Silva J, Warner F, Coppi AC, Price N, Duckwall C, Sosensky P, Di Giuseppe EC, Borg R, Fofana MO, Ranzani OT, Dean NE, Andrews JR, Croda J, Iwasaki A, Cummings DAT, Ko AI, Hitchings MDT, Schulz WL. PLoS Med. 2022 Dec; 2022 Dec 1. PMID: 36454733.
Cystic Fibrosis in the Era of Highly Effective CFTR Modulators.Britto CJ, Taylor-Cousar JL. Clin Chest Med. 2022 Dec. PMID: 36344084.
Non-Modulator Therapies: Developing a Therapy for Every Cystic Fibrosis Patient.Egan ME. Clin Chest Med. 2022 Dec. PMID: 36344076.
Novel Approaches to Multidrug-Resistant Infections in Cystic Fibrosis.Murray TS, Stanley G, Koff JL. Clin Chest Med. 2022 Dec. PMID: 36344073.
Emerging Approaches to Monitor and Modify Care in the Era of Cystic Fibrosis Transmembrane Conductance Regulators.Britto CJ, Ratjen F, Clancy JP. Clin Chest Med. 2022 Dec. PMID: 36344071.