Barbara Irene Kazmierczak, PhD, MD

Professor of Medicine (Infectious Diseases); Director, MD-PhD Program, Yale University; Professor of Microbial Pathogenesis

Departments & Organizations

Internal Medicine: CPIRT - Pulmonary Infection Research and Treatment | Infectious Diseases

Microbial Pathogenesis

Discovery to Cure Internship

MD-PhD Program: BioMed SURF

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Microbiology | Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and Physiology

Yale Medicine

Office of Cooperative Research


Dr. Kazmierczak received her Ph.D. from Rockefeller University (1993) and her M.D. from Cornell University Medical College (1994), both in New York City. She completed an Internal Medicine residency and Infectious Diseases fellowship training at the University of California, San Francisco. She began research on the opportunistic bacterial pathogen, Pseudomonas aeruginosa, while a postdoctoral scientist at UCSF.

Dr. Kazmierczak joined the faculty at Yale School of Medicine in 2001. She currently holds appointments in both Internal Medicine (Infectious Diseases) and Microbial Pathogenesis. She sees hospitalized patients as an attending physician on the Infectious Diseases consult service. Her laboratory studies the bacterial and host factors that enable environmental bacteria, such as Pseudomonas aeruginosa and Staphylococcus aureus, to cause opportunistic infections.

Education & Training

MD Cornell University Medical College (1994)
PhD Rockefeller University (1993)
BA University of Chicago (1986)
MS University of Chicago (1986)
Assistant Adjunct Professor University of California, San Francisco
Fellow University of California, San Francisco
Resident University of California, San Francisco
Intern University of California, San Francisco
Board Certification AB of Internal Medicine, Infectious Disease (1999, recertified: 2009)

Honors & Recognition

  • Elected Member, ASCIAmerican Society for Clinical Investigation (2014)

  • Visiting Faculty Research GrantDeutscher Akademischer Austausch Dienst (DAAD) (2010)

  • Elected MemberPolish Institute of Arts and Sciences in America (2009)

  • Fellow, IDSAInfectious Diseases Society of America (2008)

  • Investigator in Pathogenesis of Infectious DiseasesBurroughs Wellcome Fund (2007)

  • Investigator AwardPatrick and Catherine Weldon Donaghue Medical Research Foundation (2003)

Professional Service

  • MD-PhD Steering Committee, GREAT Group, AAMC (2017 - Present)

  • Yale University (2010 - 2014) Associate Director for Basic Research, MD-PhD Program

  • IDSA (2009 - 2012) Annual Meeting Planning Committee

  • Director of Admissions, Microbiology Program, Yale University (2004 - 2007)

  • Yale University (2004 - Present) MD/PhD Faculty Committee


  • Innate immune responses to bacterial infection Berlin, Germany (2010 - 2010)

    Visiting Researcher

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Contact Info

Barbara Irene Kazmierczak, PhD, MD
Patient Care Location
Yale Infectious DiseasesYale New Haven Hospital
20 York Street

New Haven, CT 06510
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Lab Location
The Anlyan Center
300 Cedar Street, Ste S140

New Haven, CT 06519
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Office Location
The Anlyan Center
300 Cedar Street, Ste S169B

New Haven, CT 06519
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Mailing Address
Infectious DiseasesPO Box 208056
333 Cedar Street

New Haven, CT 06520-8056
Heterogeneous expression of virulence in Pseudomonas aeruginosa

A Type 3 secretion system transcriptional reporter driving sfGFP expression reveals variation among genetically identical bacteria exposed to conditions that induce this virulence system.