Pulmonary Vascular Disease Program

Publications

2022

LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.Peng T, Liu M, Hu L, Guo D, Wang D, Qi B, Ren G, Hu C, Zhang F, Chun HJ, Song L, Hu J, Li Y. Biol Direct. 2022 Nov 16; 2022 Nov 16. PMID: 36384975.
Reply to Suresh.Bazan IS, Kim SJ, Ardito TA, Zhang Y, Shan P, Sauler M, Lee PJ. Am J Physiol Lung Cell Mol Physiol. 2022 Nov 1. PMID: 36351165.
Corrigendum to 'Impaired systemic oxygen extraction long after mild COVID-19: potential perioperative implications' (Br J Anaesth 2022; 128: e246-9).Heerdt PM, Shelley B, Singh I. Br J Anaesth. 2022 Nov; 2022 Aug 27. PMID: 36041925.
Neurovascular Dysregulation and Acute Exercise Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Placebo-Controlled Trial of Pyridostigmine.Joseph P, Pari R, Miller S, Warren A, Stovall MC, Squires J, Chang CJ, Xiao W, Waxman AB, Systrom DM. Chest. 2022 Nov; 2022 May 6. PMID: 35526605.
Endothelial β-arrestins regulate mechanotransduction by the type II bone morphogenetic protein receptor in primary cilia.Park S, Ma Z, Zarkada G, Papangeli I, Paluri S, Nazo N, Rivera-Molina F, Toomre D, Rajagopal S, Chun HJ. Pulm Circ. 2022 Oct; 2022 Oct 1. PMID: 36532314.
BMPR1A Promotes ID2-ZEB1 Interaction to Suppress Excessive Endothelial to Mesenchymal Transition.Lee HW, Adachi T, Pak B, Park S, Hu X, Choi W, Kowalski PS, Chang CH, Clapham KR, Lee A, Papangeli I, Kim J, Han O, Park J, Anderson DG, Simons M, Jin SW, Chun HJ. Cardiovasc Res. 2022 Sep 27; 2022 Sep 27. PMID: 36166408.
Short and Long Term Non-Invasive Cardiopulmonary Exercise Assessment in previously Hospitalized COVID-19 Patients.Singh I, Joseph P. Eur Respir J. 2022 Sep 22; 2022 Sep 22. PMID: 36137592.
Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung Injury.Harris ZM, Sun Y, Joerns J, Clark B, Hu B, Korde A, Sharma L, Shin HJ, Manning EP, Placek L, Unutmaz D, Stanley G, Chun H, Sauler M, Rajagopalan G, Zhang X, Kang MJ, Koff JL. Oxid Med Cell Longev. 2022; 2022 Sep 20. PMID: 36193076.
Embracing the Diversity of Latinx Communities to Promote Vaccinations.Ortiz AC, Akgün KM, Bazan IS. Yale J Biol Med. 2022 Jun; 2022 Jun 30. PMID: 35782479.
Sex differences and altered mitophagy in experimental pulmonary hypertension.Bazan IS, Kim SJ, Ardito TA, Zhang Y, Shan P, Sauler M, Lee PJ. Am J Physiol Lung Cell Mol Physiol. 2022 May 1; 2022 Feb 9. PMID: 35137625.
Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerations.Khosla A, Mojibian H, Assi R, Tantawy H, Singh I, Pollak J. Pulm Circ. 2022 Apr; 2022 Apr 25. PMID: 35514771.
Pressure-based estimation of right ventricular ejection fraction.Heerdt PM, Singh I, Elassal A, Kheyfets V, Richter MJ, Tello K. ESC Heart Fail. 2022 Apr; 2022 Feb 12. PMID: 35150211.
Association of renalase with clinical outcomes in hospitalized patients with COVID-19.Safdar B, Wang M, Guo X, Cha C, Chun HJ, Deng Y, Dziura J, El-Khoury JM, Gorelick F, Ko AI, Lee AI, Safirstein R, Simonov M, Zhou B, Desir GV. PLoS One. 2022; 2022 Mar 8. PMID: 35259186.
Impaired systemic oxygen extraction long after mild COVID-19: potential perioperative implications.Heerdt PM, Shelley B, Singh I. Br J Anaesth. 2022 Mar; 2021 Dec 27. PMID: 35067364.
Macrophage IL-1β promotes arteriogenesis by autocrine STAT3- and NF-κB-mediated transcription of pro-angiogenic VEGF-A.Mantsounga CS, Lee C, Neverson J, Sharma S, Healy A, Berus JM, Parry C, Ceneri NM, López-Giráldez F, Chun HJ, Lu Q, Sellke F, Choudhary G, Morrison AR. Cell Rep. 2022 Feb 1. PMID: 35108537.
Reply to Grignola and Trujillo.Oakland HT, Joseph P, Naeije R, Elassal A, Cullinan M, Heerdt PM, Singh I. J Appl Physiol (1985). 2022 Jan 1. PMID: 35030044.
Severe breakthrough COVID-19 cases in the SARS-CoV-2 delta (B.1.617.2) variant era.Wang SY, Juthani PV, Borges KA, Shallow MK, Gupta A, Price C, Won CH, Chun HJ. Lancet Microbe. 2022 Jan; 2021 Dec 3. PMID: 34901896.
Persistent Exertional Intolerance After COVID-19: Insights From Invasive Cardiopulmonary Exercise Testing.Singh I, Joseph P, Heerdt PM, Cullinan M, Lutchmansingh DD, Gulati M, Possick JD, Systrom DM, Waxman AB. Chest. 2022 Jan; 2021 Aug 11. PMID: 34389297.

2021

Quantification of Arterial and Venous Morphologic Markers in Pulmonary Arterial Hypertension Using CT Imaging.Rahaghi FN, Nardelli P, Harder E, Singh I, Sánchez-Ferrero GV, Ross JC, San José Estépar R, Ash SY, Hunsaker AR, Maron BA, Leopold JA, Waxman AB, San José Estépar R, Washko GR. Chest. 2021 Dec; 2021 Jul 13. PMID: 34270966.
Hospitalisation among vaccine breakthrough COVID-19 infections.Juthani PV, Gupta A, Borges KA, Price CC, Lee AI, Won CH, Chun HJ. Lancet Infect Dis. 2021 Nov; 2021 Sep 7. PMID: 34506735.
Pressure-based estimation of right ventricular ejection fraction: Validation as a clinically relevant target for drug development in a rodent model of pulmonary hypertension.Elassal A, Steppan J, Charania S, Santhanam L, Singh I, Heerdt PM. J Pharmacol Toxicol Methods. 2021 Nov-Dec; 2021 Jul 7. PMID: 34245885.
COVID-19 Healthcare Inequity: Lessons Learned from Annual Influenza Vaccination Rates to Mitigate COVID-19 Vaccine Disparities.Bazan IS, Akgün KM. Yale J Biol Med. 2021 Sep; 2021 Sep 30. PMID: 34602888.
Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data.Manning EP, Ramachandra AB, Schupp JC, Cavinato C, Raredon MSB, Bärnthaler T, Cosme C Jr, Singh I, Tellides G, Kaminski N, Humphrey JD. Front Physiol. 2021; 2021 Sep 14. PMID: 34594238.
Sex Differences and the Role of Sex Hormones in Pulmonary Hypertension.Oakland HT, Joseph P. Clin Chest Med. 2021 Sep. PMID: 34353451.
Association of obesity with venous thromboembolism and myocardial injury in COVID-19.Wang SY, Singh A, Eder MD, Vadlamani L, Lee AI, Chun HJ, Desai NR. Obes Res Clin Pract. 2021 Sep-Oct; 2021 Jul 16. PMID: 34281793.
Liver injury in COVID-19 and IL-6 trans-signaling-induced endotheliopathy.McConnell MJ, Kawaguchi N, Kondo R, Sonzogni A, Licini L, Valle C, Bonaffini PA, Sironi S, Alessio MG, Previtali G, Seghezzi M, Zhang X, Lee AI, Pine AB, Chun HJ, Zhang X, Fernandez-Hernando C, Qing H, Wang A, Price C, Sun Z, Utsumi T, Hwa J, Strazzabosco M, Iwakiri Y. J Hepatol. 2021 Sep; 2021 May 13. PMID: 33991637.
Defining end-systolic pressure for single-beat estimation of right ventricle-pulmonary artery coupling: simple… but not really.Singh I, Oakland H, Elassal A, Heerdt PM. ERJ Open Res. 2021 Jul; 2021 Aug 23. PMID: 34435035.
Chronic Thromboembolic Pulmonary Hypertension: the Bedside.Matusov Y, Singh I, Yu YR, Chun HJ, Maron BA, Tapson VF, Lewis MI, Rajagopal S. Curr Cardiol Rep. 2021 Aug 19; 2021 Aug 19. PMID: 34410530.
Chronic Thromboembolic Pulmonary Hypertension: the Bench.Alba GA, Atri D, Darbha S, Singh I, Tapson VF, Lewis MI, Chun HJ, Yu YR, Maron BA, Rajagopal S. Curr Cardiol Rep. 2021 Aug 19; 2021 Aug 19. PMID: 34410515.
Challenges in interpreting cytokine data in COVID-19 affect patient care and management.Wang SY, Takahashi T, Pine AB, Damsky WE, Simonov M, Zhang Y, Kieras E, Price CC, King BA, Siegel MD, Desir GV, Lee AI, Iwasaki A, Chun HJ. PLoS Biol. 2021 Aug; 2021 Aug 6. PMID: 34358229.
Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.Joseph P, Arevalo C, Oliveira RKF, Faria-Urbina M, Felsenstein D, Oaklander AL, Systrom DM. Chest. 2021 Aug; 2021 Feb 10. PMID: 33577778.
Immunofibrotic drivers of impaired lung function in postacute sequelae of SARS-CoV-2 infection.Chun HJ, Coutavas E, Pine AB, Lee AI, Yu VL, Shallow MK, Giovacchini CX, Mathews AM, Stephenson B, Que LG, Lee PJ, Kraft BD. JCI Insight. 2021 Jul 22; 2021 Jul 22. PMID: 34111030.
Author Correction: Delayed production of neutralizing antibodies correlates with fatal COVID-19.Lucas C, Klein J, Sundaram ME, Liu F, Wong P, Silva J, Mao T, Oh JE, Mohanty S, Huang J, Tokuyama M, Lu P, Venkataraman A, Park A, Israelow B, Vogels CBF, Muenker MC, Chang CH, Casanovas-Massana A, Moore AJ, Zell J, Fournier JB, Wyllie AL, Campbell M, Lee AI, Chun HJ, Grubaugh ND, Schulz WL, Farhadian S, Dela Cruz C, Ring AM, Shaw AC, Wisnewski AV, Yildirim I, Ko AI, Omer SB, Iwasaki A. Nat Med. 2021 Jul. PMID: 34145437.
Arterial load and right ventricular-vascular coupling in pulmonary hypertension.Oakland H, Joseph P, Naeije R, Elassal A, Cullinan M, Heerdt PM, Singh I. J Appl Physiol (1985). 2021 Jul 1; 2021 May 27. PMID: 34043473.
Delayed production of neutralizing antibodies correlates with fatal COVID-19.Lucas C, Klein J, Sundaram ME, Liu F, Wong P, Silva J, Mao T, Oh JE, Mohanty S, Huang J, Tokuyama M, Lu P, Venkataraman A, Park A, Israelow B, Vogels CBF, Muenker MC, Chang CH, Casanovas-Massana A, Moore AJ, Zell J, Fournier JB, Wyllie AL, Campbell M, Lee AI, Chun HJ, Grubaugh ND, Schulz WL, Farhadian S, Dela Cruz C, Ring AM, Shaw AC, Wisnewski AV, Yildirim I, Ko AI, Omer SB, Iwasaki A. Nat Med. 2021 Jul; 2021 May 5. PMID: 33953384.
Interleukin-1- Receptor Kinase 4 Inhibition: Achieving Immunomodulatory Synergy to Mitigate the Impact of COVID-19.Gupta A, Chun HJ. Front Immunol. 2021; 2021 Jun 23. PMID: 34248990.
Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients.McAlpine LS, Zubair AS, Maran I, Chojecka P, Lleva P, Jasne AS, Navaratnam D, Matouk C, Schindler J, Sheth KN, Chun H, Lee AI, Spudich S, Sharma R, Sansing LH. Stroke. 2021 Jun; 2021 May 10. PMID: 33966492.
Sex-Related Differences in Dynamic Right Ventricular-Pulmonary Vascular Coupling in Heart Failure With Preserved Ejection Fraction.Singh I, Oliveira RKF, Heerdt PM, Pari R, Systrom DM, Waxman AB. Chest. 2021 Jun; 2021 Jan 1. PMID: 33388286.
Impact of right ventricular work and pulmonary arterial compliance on peak exercise oxygen uptake in idiopathic pulmonary arterial hypertension.Messina CMS, Ferreira EVM, Singh I, Fonseca AXC, Ramos RP, Nery LE, Systrom DM, Oliveira RKF, Ota-Arakaki JS. Int J Cardiol. 2021 May 15; 2021 Feb 3. PMID: 33545265.
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.Ma L, Sahu SK, Cano M, Kuppuswamy V, Bajwa J, McPhatter J, Pine A, Meizlish ML, Goshua G, Chang CH, Zhang H, Price C, Bahel P, Rinder H, Lei T, Day A, Reynolds D, Wu X, Schriefer R, Rauseo AM, Goss CW, O’Halloran JA, Presti RM, Kim AH, Gelman AE, Dela Cruz CS, Lee AI, Mudd PA, Chun HJ, Atkinson JP, Kulkarni HS. Sci Immunol. 2021 May 13. PMID: 34446527.
Refining drug-eluting stent technologies: from engineering to basic science.Lansky A, Chun H, Pietras C, Hussain Y. Eur Heart J. 2021 May 7. PMID: 33624813.
Immuno-fibrotic drivers of impaired lung function in post-acute sequelae of SARS-CoV-2 infection (PASC).Chun HJ, Coutavas E, Pine A, Lee AI, Yu V, Shallow M, Giovacchini CX, Mathews A, Stephenson B, Que LG, Lee PJ, Kraft BD. medRxiv. 2021 Apr 21; 2021 Apr 21. PMID: 33564789.
Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: A propensity score-matched analysis.Meizlish ML, Goshua G, Liu Y, Fine R, Amin K, Chang E, DeFilippo N, Keating C, Liu Y, Mankbadi M, McManus D, Wang SY, Price C, Bona RD, Ochoa Chaar CI, Chun HJ, Pine AB, Rinder HM, Siner JM, Neuberg DS, Owusu KA, Lee AI. Am J Hematol. 2021 Apr 1; 2021 Feb 22. PMID: 33476420.
Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension.Ntokou A, Dave JM, Kauffman AC, Sauler M, Ryu C, Hwa J, Herzog EL, Singh I, Saltzman WM, Greif DM. JCI Insight. 2021 Mar 22; 2021 Mar 22. PMID: 33591958.
A neutrophil activation signature predicts critical illness and mortality in COVID-19.Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. Blood Adv. 2021 Mar 9. PMID: 33635335.
Systemic vascular distensibility relates to exercise capacity in connective tissue disease.Singh I, Oliveira RKF, Naeije R, Oldham WM, Faria-Urbina M, Waxman AB, Systrom DM. Rheumatology (Oxford). 2021 Mar 2. PMID: 33001175.
Pulmonary Hypertension: An Integrative Approach to Assessment and Management.Waxman AB, Singh I. Clin Chest Med. 2021 Mar. PMID: 33541622.
Pulmonary Hypertension in Pregnancy.Singh I, Horn E, Haythe J. Clin Chest Med. 2021 Mar; 2021 Jan 9. PMID: 33541621.
The Evolution in Nomenclature, Diagnosis, and Classification of Pulmonary Hypertension.Fouad J, Joseph P. Clin Chest Med. 2021 Mar; 2021 Jan 8. PMID: 33541603.
Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation.Gu SX, Tyagi T, Jain K, Gu VW, Lee SH, Hwa JM, Kwan JM, Krause DS, Lee AI, Halene S, Martin KA, Chun HJ, Hwa J. Nat Rev Cardiol. 2021 Mar; 2020 Nov 19. PMID: 33214651.
A Clinic Blueprint for Post-Coronavirus Disease 2019 RECOVERY: Learning From the Past, Looking to the Future.Lutchmansingh DD, Knauert MP, Antin-Ozerkis DE, Chupp G, Cohn L, Dela Cruz CS, Ferrante LE, Herzog EL, Koff J, Rochester CL, Ryu C, Singh I, Tickoo M, Winks V, Gulati M, Possick JD. Chest. 2021 Mar; 2020 Nov 4. PMID: 33159907.
The emerging role of Janus kinase inhibitors in the treatment of autoimmune and inflammatory diseases.Damsky W, Peterson D, Ramseier J, Al-Bawardy B, Chun H, Proctor D, Strand V, Flavell RA, King B. J Allergy Clin Immunol. 2021 Mar; 2020 Oct 28. PMID: 33129886.
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.Ma L, Sahu SK, Cano M, Kuppuswamy V, Bajwa J, McPhatter J, Pine A, Meizlish M, Goshua G, Chang CH, Zhang H, Price C, Bahel P, Rinder H, Lei T, Day A, Reynolds D, Wu X, Schriefer R, Rauseo AM, Goss CW, O'Halloran JA, Presti RM, Kim AH, Gelman AE, Cruz CD, Lee AI, Mudd P, Chun HJ, Atkinson JP, Kulkarni HS. bioRxiv. 2021 Feb 23; 2021 Feb 23. PMID: 33655244.
MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease.Nouws J, Wan F, Finnemore E, Roque W, Kim SJ, Bazan I, Li CX, Skold CM, Dai Q, Yan X, Chioccioli M, Neumeister V, Britto CJ, Sweasy J, Bindra R, Wheelock ÅM, Gomez JL, Kaminski N, Lee PJ, Sauler M. JCI Insight. 2021 Jan 25; 2021 Jan 25. PMID: 33290275.
Collateral Damage: Gun Violence-Induced STEMI.Shah NN, Kay B, Jiang NM, Chun HJ. JACC Case Rep. 2021 Jan; 2021 Jan 20. PMID: 34317462.
Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: a propensity score-matched analysis.Meizlish ML, Goshua G, Liu Y, Fine R, Amin K, Chang E, DeFilippo N, Keating C, Liu Y, Mankbadi M, McManus D, Wang S, Price C, Bona RD, Chaar CIO, Chun HJ, Pine AB, Rinder HM, Siner J, Neuberg DS, Owusu KA, Lee AI. medRxiv. 2021 Jan 15; 2021 Jan 15. PMID: 33469595.

2020

Diagnostic utility of sub-maximum cardiopulmonary exercise testing in the ambulatory setting for heart failure with preserved ejection fraction.Oakland HT, Joseph P, Elassal A, Cullinan M, Heerdt PM, Singh I. Pulm Circ. 2020 Oct-Dec; 2020 Nov 25. PMID: 33282205.
Circulating markers of angiogenesis and endotheliopathy in COVID-19.Pine AB, Meizlish ML, Goshua G, Chang CH, Zhang H, Bishai J, Bahel P, Patel A, Gbyli R, Kwan JM, Won CH, Price C, Dela Cruz CS, Halene S, van Dijk D, Hwa J, Lee AI, Chun HJ. Pulm Circ. 2020 Oct-Dec; 2020 Nov 25. PMID: 33282193.
Dynamic right ventricular function response to incremental exercise in pulmonary hypertension.Singh I, Oliveira RKF, Heerdt P, Brown MB, Faria-Urbina M, Waxman AB, Systrom DM. Pulm Circ. 2020 Jul-Sep; 2020 Oct 2. PMID: 33062259.
Fick principle and exercise pulmonary hemodynamic determinants of the six-minute walk distance in pulmonary hypertension.Joseph P, Oliveira RKF, Eslam RB, Agarwal M, Waxman AB, Systrom DM. Pulm Circ. 2020 Jul-Sep; 2020 Sep 11. PMID: 32994925.
Aortic valve calcification predicts all-cause mortality independent of coronary calcification and severe stenosis.Christensen JL, Tan S, Chung HE, Ghosalkar DS, Qureshi R, Chu A, Yu W, Berus J, Shah NR, Wu WC, Chun H, Aikawa E, Choudhary G, Morrison AR. Atherosclerosis. 2020 Aug; 2020 Jul 8. PMID: 32702536.
Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study.Goshua G, Pine AB, Meizlish ML, Chang CH, Zhang H, Bahel P, Baluha A, Bar N, Bona RD, Burns AJ, Dela Cruz CS, Dumont A, Halene S, Hwa J, Koff J, Menninger H, Neparidze N, Price C, Siner JM, Tormey C, Rinder HM, Chun HJ, Lee AI. Lancet Haematol. 2020 Aug; 2020 Jun 30. PMID: 32619411.
A 50-Year-Old Woman With Limited Scleroderma Presenting With Shortness of Breath.Walia A, Singh I, Ryu C, Lutchmansingh DD. Chest. 2020 Jul; 2020 Jul 2. PMID: 32654737.
Circulating Markers of Angiogenesis and Endotheliopathy in COVID-19.Meizlish ML, Pine AB, Goshua G, Chang CH, Zhang H, Bishai J, Bahel P, Patel A, Gbyli R, Kwan J, Price C, Cruz CSD, Halene S, van Dijk D, Hwa J, Lee AI, Chun HJ. medRxiv. 2020 Jul 1; 2020 Jul 1. PMID: 32637968.
A pressure-based single beat method for estimation of right ventricular ejection fraction: proof of concept.Heerdt PM, Kheyfets V, Charania S, Elassal A, Singh I. Eur Respir J. 2020 Mar; 2020 Mar 12. PMID: 31771999.

2019

The apelinergic system: a perspective on challenges and opportunities in cardiovascular and metabolic disorders.Marsault E, Llorens-Cortes C, Iturrioz X, Chun HJ, Lesur O, Oudit GY, Auger-Messier M. Ann N Y Acad Sci. 2019 Nov; 2019 Jun 25. PMID: 31236974.
Right Ventricular-Arterial Uncoupling During Exercise in Heart Failure With Preserved Ejection Fraction: Role of Pulmonary Vascular Dysfunction.Singh I, Rahaghi FN, Naeije R, Oliveira RKF, Systrom DM, Waxman AB. Chest. 2019 Nov; 2019 May 16. PMID: 31103695.
Pulmonary Vascular Distensibility and Early Pulmonary Vascular Remodeling in Pulmonary Hypertension.Singh I, Oliveira RKF, Naeije R, Rahaghi FN, Oldham WM, Systrom DM, Waxman AB. Chest. 2019 Oct; 2019 May 20. PMID: 31121149.
Dynamic right ventricular-pulmonary arterial uncoupling during maximum incremental exercise in exercise pulmonary hypertension and pulmonary arterial hypertension.Singh I, Rahaghi FN, Naeije R, Oliveira RKF, Vanderpool RR, Waxman AB, Systrom DM. Pulm Circ. 2019 Jul-Sep. PMID: 31218910.
MEF2 and the Right Ventricle: From Development to Disease.Clapham KR, Singh I, Capuano IS, Rajagopal S, Chun HJ. Front Cardiovasc Med. 2019; 2019 Mar 28. PMID: 30984767.
Cell Death in the Lung: The Apoptosis-Necroptosis Axis.Sauler M, Bazan IS, Lee PJ. Annu Rev Physiol. 2019 Feb 10; 2018 Nov 28. PMID: 30485762.
Pulmonary artery pseudoaneurysm causing massive hemoptysis in hyperimmunoglobulin E syndrome: a case report.Hakim A, Bazan IS, Sanogo ML, Manning EP, Pollak JS, Chupp GL. BMC Pulm Med. 2019 Feb 8; 2019 Feb 8. PMID: 30736787.
Malignant Pleural Effusion at Presentation in Patients with Small-Cell Lung Cancer.Shojaee S, Singh I, Solsky I, Nana-Sinkam P. Respiration. 2019; 2019 May 23. PMID: 31121583.

2018

Therapeutic Engagement of the Histone Deacetylase IIA-Myocyte Enhancer Factor 2 Axis Improves Experimental Pulmonary Hypertension.Sofer A, Lee S, Papangeli I, Adachi T, Hwangbo C, Comhair S, DaSilva-Jardine P, Kim J, Schwarz JJ, Erzurum SC, Chun HJ. Am J Respir Crit Care Med. 2018 Nov 15. PMID: 30106596.
Hypercoagulability in Pulmonary Hypertension.Bazan IS, Fares WH. Clin Chest Med. 2018 Sep. PMID: 30122183.
Mitochondrial dysfunction and pulmonary hypertension: cause, effect, or both.Marshall JD, Bazan I, Zhang Y, Fares WH, Lee PJ. Am J Physiol Lung Cell Mol Physiol. 2018 May 1; 2018 Jan 18. PMID: 29345195.
Staged Endovascular Intervention of Bilateral Pulmonary Artery Stenosis.Goljo E, Bazan IS, Brandt EJ, Fares WH, Asnes JD. JACC Cardiovasc Interv. 2018 Mar 26. PMID: 29566807.
Pulmonary arterial hypertension in the setting of scleroderma is different than in the setting of lupus: A review.Bazan IS, Mensah KA, Rudkovskaia AA, Adonteng-Boateng PK, Herzog EL, Buckley L, Fares WH. Respir Med. 2018 Jan; 2017 Dec 2. PMID: 29413506.

2017

A Tale of Two Elabela Null Mice.Papangeli I, Chun HJ. Trends Endocrinol Metab. 2017 Nov; 2017 Sep 27. PMID: 28964631.
Reply: Transforming Growth Factor β1- and Bone Morphogenetic Protein 2/PPARγ-regulated MicroRNAs in Pulmonary Arterial Hypertension.Chun HJ, Bonnet S, Chan SY. Am J Respir Crit Care Med. 2017 Nov 1. PMID: 28653904.
Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.Hwangbo C, Wu J, Papangeli I, Adachi T, Sharma B, Park S, Zhao L, Ju H, Go GW, Cui G, Inayathullah M, Job JK, Rajadas J, Kwei SL, Li MO, Morrison AR, Quertermous T, Mani A, Red-Horse K, Chun HJ. Sci Transl Med. 2017 Sep 13. PMID: 28904225.
Enhancing Insights into Pulmonary Vascular Disease through a Precision Medicine Approach. A Joint NHLBI-Cardiovascular Medical Research and Education Fund Workshop Report.Newman JH, Rich S, Abman SH, Alexander JH, Barnard J, Beck GJ, Benza RL, Bull TM, Chan SY, Chun HJ, Doogan D, Dupuis J, Erzurum SC, Frantz RP, Geraci M, Gillies H, Gladwin M, Gray MP, Hemnes AR, Herbst RS, Hernandez AF, Hill NS, Horn EM, Hunter K, Jing ZC, Johns R, Kaul S, Kawut SM, Lahm T, Leopold JA, Lewis GD, Mathai SC, McLaughlin VV, Michelakis ED, Nathan SD, Nichols W, Page G, Rabinovitch M, Rich J, Rischard F, Rounds S, Shah SJ, Tapson VF, Lowy N, Stockbridge N, Weinmann G, Xiao L. Am J Respir Crit Care Med. 2017 Jun 15. PMID: 28430547.
Modulation of Endothelial Bone Morphogenetic Protein Receptor Type 2 Activity by Vascular Endothelial Growth Factor Receptor 3 in Pulmonary Arterial Hypertension.Hwangbo C, Lee HW, Kang H, Ju H, Wiley DS, Papangeli I, Han J, Kim JD, Dunworth WP, Hu X, Lee S, El-Hely O, Sofer A, Pak B, Peterson L, Comhair S, Hwang EM, Park JY, Thomas JL, Bautch VL, Erzurum SC, Chun HJ, Jin SW. Circulation. 2017 Jun 6; 2017 Mar 29. PMID: 28356442.
A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis.Lee A, Papangeli I, Park Y, Jeong HN, Choi J, Kang H, Jo HN, Kim J, Chun HJ. Sci Rep. 2017 May 31; 2017 May 31. PMID: 28566713.
Relative predictive value of lung cancer screening CT versus myocardial perfusion attenuation correction CT in the evaluation of coronary calcium.Bailey G, Healy A, Young BD, Sharma E, Meadows J, Chun HJ, Wu WC, Choudhary G, Morrison AR. PLoS One. 2017; 2017 Apr 24. PMID: 28437443.
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi MM, Bender JR, Morrison AR. Arterioscler Thromb Vasc Biol. 2017 Feb; 2016 Nov 10. PMID: 27834690.
Translational Advances in the Field of Pulmonary Hypertension. Translating MicroRNA Biology in Pulmonary Hypertension. It Will Take More Than "miR" Words.Chun HJ, Bonnet S, Chan SY. Am J Respir Crit Care Med. 2017 Jan 15. PMID: 27648944.

2016

Review of the Ongoing Story of Appetite Suppressants, Serotonin Pathway, and Pulmonary Vascular Disease.Bazan IS, Fares WH. Am J Cardiol. 2016 May 15; 2016 Mar 2. PMID: 27018933.
MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation.Papangeli I, Kim J, Maier I, Park S, Lee A, Kang Y, Tanaka K, Khan OF, Ju H, Kojima Y, Red-Horse K, Anderson DG, Siekmann AF, Chun HJ. Nat Commun. 2016 Apr 12; 2016 Apr 12. PMID: 27068353.
miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart.Li N, Hwangbo C, Jaba IM, Zhang J, Papangeli I, Han J, Mikush N, Larrivée B, Eichmann A, Chun HJ, Young LH, Tirziu D. Sci Rep. 2016 Feb 18; 2016 Feb 18. PMID: 26888314.

2015

Pulmonary hypertension: diagnostic and therapeutic challenges.Bazan IS, Fares WH. Ther Clin Risk Manag. 2015; 2015 Aug 17. PMID: 26316767.
Letter by Papangeli et al Regarding Article, "The ERG-APLNR Axis Controls Pulmonary Venule Endothelial Proliferation in Pulmonary Veno-Occlusive Disease".Papangeli I, Sharma B, Chun HJ. Circulation. 2015 Jul 14. PMID: 26169651.
Elafin in pulmonary arterial hypertension. Beyond targeting elastases.Chun HJ, Yu PB. Am J Respir Crit Care Med. 2015 Jun 1. PMID: 26029832.
Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.Kim J, Hwangbo C, Hu X, Kang Y, Papangeli I, Mehrotra D, Park H, Ju H, McLean DL, Comhair SA, Erzurum SC, Chun HJ. Circulation. 2015 Jan 13; 2014 Oct 21. PMID: 25336633.

2014

Endothelium as a gatekeeper of fatty acid transport.Mehrotra D, Wu J, Papangeli I, Chun HJ. Trends Endocrinol Metab. 2014 Feb; 2013 Dec 3. PMID: 24315207.
Essential role of Apelin signaling during lymphatic development in zebrafish.Kim JD, Kang Y, Kim J, Papangeli I, Kang H, Wu J, Park H, Nadelmann E, Rockson SG, Chun HJ, Jin SW. Arterioscler Thromb Vasc Biol. 2014 Feb; 2013 Dec 5. PMID: 24311379.

2013

Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development.Kang Y, Kim J, Anderson JP, Wu J, Gleim SR, Kundu RK, McLean DL, Kim JD, Park H, Jin SW, Hwa J, Quertermous T, Chun HJ. Circ Res. 2013 Jun 21; 2013 Apr 19. PMID: 23603510.
Severe obstructive sleep apnea increases mortality in patients with ischemic heart disease and myocardial injury.Won CH, Chun HJ, Chandra SM, Sarinas PS, Chitkara RK, Heidenreich PA. Sleep Breath. 2013 Mar. PMID: 22294346.
An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension.Kim J, Kang Y, Kojima Y, Lighthouse JK, Hu X, Aldred MA, McLean DL, Park H, Comhair SA, Greif DM, Erzurum SC, Chun HJ. Nat Med. 2013 Jan; 2012 Dec 23. PMID: 23263626.

2012

Apelin/APJ signaling is a critical regulator of statin effects in vascular endothelial cells--brief report.McLean DL, Kim J, Kang Y, Shi H, Atkins GB, Jain MK, Chun HJ. Arterioscler Thromb Vasc Biol. 2012 Nov; 2012 Sep 20. PMID: 22995518.