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Yale Adult Cystic Fibrosis Center

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The Yale Adult Cystic Fibrosis Center, accredited by the national Cystic Fibrosis Foundation, specializes in the diagnosis, management, treatment and research of cystic fibrosis. We provide a team approach to care that includes medical, nurse, registered dietician, physical therapy, social worker, and respiratory therapy cystic fibrosis specialists. We collaborate closely with our colleagues in the Yale Pediatric Cystic Fibrosis Center to assist adolescents and young adults in the transition from pediatric to adult care.

Our mission

  1. To provide effective, evidence-based care for adults with cystic fibrosis.
  2. To investigate and to implement new treatments for cystic fibrosis.
  3. To advance the scientific understanding of cystic fibrosis.
  4. To train providers of adult cystic fibrosis care.

Our services

  • Comprehensive cystic fibrosis diagnosis including sweat testing and blood testing for all known mutations related to cystic fibrosis.
  • Full range of treatments for all complications related to cystic fibrosis, including those involving the respiratory, sinus, digestive, endocrine, and reproductive systems.
  • Management of cystic fibrosis lung disease, including mucus clearance techniques, mucolytics, and preventive therapy for patients infected with pseudomonas.
  • Comprehensive nutrition counseling and care, including pancreatic enzyme replacement therapy, screening for and repletion of vitamin deficiencies.
  • Cystic fibrosis education and counseling.

Latest News


  • Jon Koff

    Director, Yale Adult Cystic Fibrosis

    Associate Professor Term; Associate Director, Fellowship Research, Pulmonary, Critical Care & Sleep Medicine; Director, Adult Cystic Fibrosis Program

    Research Interests
    • Asthma
    • Bronchiectasis
    • Cystic Fibrosis
    • Immunity, Innate
    • Influenza, Human
    • Lung
    • Viruses
    • Immunity, Mucosal
    • Respiratory Mucosa
    Clinical Interests
    • Cystic Fibrosis
  • Clemente Britto-Leon

    Assistant Professor of Medicine (Pulmonary)

    Research Interests
    • Bacterial Infections and Mycoses
    • Cystic Fibrosis
    • Epithelium
    • Immune System Diseases
    • Lung
    • Respiratory Tract Diseases
    • Pulmonary Medicine
    • Airway Management
  • Jaideep S. Talwalkar

    Associate Professor of Internal Medicine (General Medicine); Associate Director, Yale Cystic Fibrosis Adult Program, Pulmonary, Critical Care & Sleep Medicine; Associate Program Director, Yale Combined Med-Peds Residency Program; Director of Clinical Skills, Office of Education; Faculty Advisor, Yale Resident Spanish-language Initiative

    Research Interests
    • Curriculum
    • Cystic Fibrosis
    • Education, Medical
    • Internal Medicine
    • Pediatrics

Contact Us

Winchester Chest Clinic
Fitkin Memorial Pavilion
789 Howard Ave, 2nd Floor
New Haven, CT 06519

Appt: (203) 785-4198
Fax: (203) 737-5453