Wenwei Li

I am very happy to join in Mothes lab. I work on projects to understand the conformational changes of HIV-1 envelope glycoprotein on the surface of virus particles by parallel cryo Electron Tomography (CryoET) and single molecule Forster Resonance Energy Transfer (smFRET). I am also working on COVID19 research to understand the structural conformational change of spike protein of SARS-CoV-2. These projects will provide insights into not only basic science like how envelope mediates fusion of virus with host cell but also translational science aiding an vaccine and anti-retroviral therapies.