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Maor Sauler, MD

Assistant Professor of Medicine (Pulmonary)

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Maor Sauler, MD

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Biography

Maor Sauler has been a member of the Pulmonary & Critical Care faculty since 2014. Dr. Sauler specializes in adult critical care including acute lung injury and sepsis. He also sees patients in the outpatient setting with pulmonary diseases such as Chronic Obstructive Pulmonary Disease (COPD). Dr. Sauler is board-certified in internal medicine, pulmonary medicine, and critical care medicine.

Dr. Sauler earned his undergraduate degree from Princeton University and received his MD from Rutgers-New Jersey Medical School. Dr. Sauler then completed both an internship and residency in internal medicine at Yale-New Haven Hospital. He went on to complete fellowship training in pulmonary and critical care medicine at Yale-School of Medicine.

The overall goal of Dr. Sauler's research program is to study biologic mechanisms that maintain lung "resilience" in response to oxidative stress and DNA damage. His research focuses on understanding cellular stress responses that change with age or with COPD, and then try to identify mechanisms through which these aberrant cellular stress responses contribute to susceptibility to injury, excessive inflammation, or abnormal lung repair. To do this, his lab integrates lung- and cell-targeted genetic mouse models, cell-based assays, novel imaging techniques, and multiple high-throughput genomic approaches. His work has focused on the role of Macrophage Migration Inhibitory Factor (MIF), a canonical innate immune cytokine that is secreted in response to oxidative stress, DNA damage, and infection. Dr. Sauler's lab has identified mechanisms through which this cytokine can mitigate oxidative stress, cellular senescence, and apoptosis, and promote tissue repair. His research has also demonstrated that expression of DNA repair enzymes are decreased in COPD and he has identified a dysregulated miR-24-3p/BRCA1 signaling network that may contribute to COPD pathogenesis.




Education & Training

  • Fellow
    Yale School of Medicine (2014)
  • Resident
    Yale-New Haven Hospital (2009)
  • Intern
    Yale-New Haven Hospital (2007)
  • MD
    Rutgers New Jersey Medical School (2006)
  • BA
    Princeton University (2001)

Honors & Recognition

AwardAwarding OrganizationDate
K08 Career Development AwardNational Institute of Health, NHLBI2017
Young Clinical Scientist AwardFlight Attendant Medical Research Institute2015
Abstract Scholarship AwardAmerican Thoracic Society2015
Parker B. Francis FellowshipFrancis Ford Foundation2015
Distinction in ScholarshipAmerican Physiology Society2014
Senior Research Training FellowshipAmerican Lung Association2013
Respiratory DIsease Young Investigators' Forum, Top Presentation Award2013

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