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Evangelos Oikonomou, MD, DPhil

Clinical Fellow; Cardiovascular Medicine, Yale School of Medicine

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Evangelos Oikonomou, MD, DPhil


Evangelos (Evan) Oikonomou is a clinical fellow in cardiovascular medicine and a member of the ABIM Physician-Scientist Research Pathway at Yale School of Medicine. He holds a medical degree from the University of Athens (Greece), and a Ph.D. (D.Phil.) in Medical Sciences from the University of Oxford (United Kingdom). As a Ph.D. student in Oxford (Division of Cardiovascular Medicine, Radcliffe Department of Medicine), Evangelos investigated the biological interplay between the perivascular adipose tissue and human vasculature. During the course of his project "Non-invasive phenotyping of perivascular adipose tissue for cardiovascular disease diagnosis and risk stratification", he developed and validated a machine learning radiomic approach to better characterize the role of perivascular inflammation in atherosclerosis. As a physician-scientist at Yale and a member of the Cardiovascular Data Science (CarDS) Lab (led by Dr Rohan Khera), Evangelos is interested in applying multi-modal machine learning approaches (using a mixture of unstructured and structured data types) to personalize the diagnosis and treatment of cardiovascular disease. His most recent work has focused on the use of phenomapping strategies to derive personalized effect estimates from randomized controlled trials, as well as on the deep learning phenotyping of echocardiograms for early disease diagnosis. His work has been published in several peer-reviewed journals, including the Lancet, Lancet Digital Health, European Heart Journal, JACC, Circulation, JAMA Cardiology, Diabetes Care.

Education & Training

  • Clinical fellow
    Yale School of Medicine (2023)
  • Resident
    Yale School of Medicine (2021)
  • Intern
    Yale School of Medicine (2020)
  • DPhil
    University of Oxford (2019)
  • MD
    University of Athens School of Health Sciences (2015)

Honors & Recognition

AwardAwarding OrganizationDate
Elizabeth Barrett-Connor Research Award in Epidemiology and Prevention (Winner)American Heart Association2023
Ruth L. Kirschstein Postdoctoral Individual National Research Service Award (F32)National Heart, Lung, and Blood Institute (NIH)2023
Yale/Mayo CERSI scholar 2022-2023Yale University & Mayo Clinic Center for Excellence in Regulatory Science and Innovation (CERSI)2022
Council on Lifestyle and Cardiometabolic Health Early Career Investigator AwardAmerican Heart Association2021
First Place Award (Clinical Fellows)Northwestern Cardiovascular Young Investigators' Forum2021
Young Investigator Award in Population Science (Winner)European Association of Preventive Cardiology2021
Young Investigator Award in Clinical Science (Winner)European Society of Cardiology Congress 20192019
Radcliffe Department of Medicine Graduate PrizeUniversity of Oxford2018
Young Investigator Award in Clinical Science (Winner)European Society of Cardiology Congress 20182018
Paul Dudley White international ScholarAmerican Heart Association2017
Toshiba Young Investigator Award (Winner)Society of Cardiovascular Computed Tomography2017
Class ValedictorianUniversity of Athens2015

Professional Service

European Heart JournalReviewer2020 - Present
CirculationReviewer2020 - Present
JACC: Cardiovascular ImagingReviewer2020 - Present
JACC: Journal of the American College of CardiologyReviewer2020 - Present
Cardiovascular ResearchReviewer2018 - Present
American Journal of CardiologyReviewer2017 - Present

Departments & Organizations