Brian Joseph Clark, MD


Departments & Organizations

Internal Medicine: Pulmonary, Critical Care & Sleep Medicine

Yale Medicine


Residency: Northwestern University

Research: Acute lung injury (ALI) is a common illness in intensive care units with a significant morbidity and mortality. Currently, the treatment of ALI focuses primarily on supportive care and, if known, treatment of the underlying cause. My research focuses on the signaling in the alveolar epithelium involved in the propagation of acute lung injury. In the laboratory, my experiments use human and murine cells in vitro and murine models of ALI in vivo to investigate signaling pathways important in ALI. The eventual goal of my research is to identify potentially novel therapeutic targets for the prevention and treatment of acute lung injury.

Mentors: Jonathan Koff, MD

Education & Training

MD Northwestern University (2010)
BA Hamilton College (2004)
Board Certification AB of Internal Medicine, Internal Medicine (2013, recertified: 2015)
Board Certification AB of Internal Medicine, Pulmonary Disease (2016)
Board Certification AB of Internal Medicine, Critical Care Medicine (Internal Medicine) (2017)

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Brian Joseph Clark, MD

Curriculum Vitae