Martin Schwartz, PhD

Robert W. Berliner Professor of Medicine (Cardiology) and Professor of Biomedical Engineering and of Cell Biology

Departments & Organizations

Cell Biology: Cytoskeletal Dynamics | Developmental Cell Biology and Genetics

Internal Medicine: Cardiovascular Medicine: Yale Cardiovascular Research Center: Schwartz Lab | Diabetes Research Center

Vascular Biology and Therapeutics Program

Yale Cancer Center: Signal Transduction

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development

Leducq TNE


Martin Schwartz earned a BA in chemistry from New College in Sarasota FL and a PhD in physical chemistry from Stanford, where he worked in Harden McConnell’s lab on biophysics of phospholipid membranes.He then did postdoctoral research in biology at MIT in the laboratory of Richard Hynes where he studied interactions of fibronectin with cells and other proteins. He was on the faculty at Harvard Medical School, Scripps Research Institute and the University of Virginia prior to moving to Yale in 2011. Starting in the 1980’s, his lab was among the first to report that integrin mediated adhesion could regulate signaling pathways in cells;that integrin-mediated adhesion promotes cell survival, that integrins synergize with growth factor receptors to activate growth signaling pathways and that integrins regulate Rho family GTPases. His lab has also elucidated mechanotransduction pathways by which endothelial cells respond to fluid shear stress to activate inflammatory pathways linked to atherosclerosis. His current research program combines studies using biophysical, cellular and animal approaches to important questions about integrin signaling, mechanotransduction and disease in the vascular system.

Education & Training

PhD Stanford University (1979)
BA New College of the University South Florida (1975)
Postdoctoral fellow MIT

Honors & Recognition

  • Fellow of the American Society for Cell BiologyAmerican Society for Cell Biology (2017)

  • Fellow of the American Association for Advancement of ScienceAmerican Association for Advancement of Science (2016)

  • Harold F. Dvorak Plenary LectureHarvard Medical School (2013)

  • Andrew P. Somlyo Honorary LecturePennsylvania Muscle Institute, University of Pennsylvania (2013)

  • Robert W. Berliner Professor of MedicineYale School of Medicine (2012)

  • Hayashi Lecturer, Woods Hole MBL Physiology CourseMarine Biology Laboratory (2009)

  • James O. Davis LectureshipUniversity of Missouri (2009)

Professional Service

  • Gordon Research Conference, Signaling by Cell Adhesion Receptor (2012) Chairperson

  • Frontiers in Cell Migration & Mechanotransduction (2011) Chairperson

  • Gordon Research Conference, Vascular Cell Biology (2011) Chairperson

  • Mechanotransduction in Physiology and Disease (2009) Chairperson

  • Keystone conference on Signaling by Integrins and Growth Factor Receptors (1998) Chairperson

  • Keystone conference on Integrins and Signaling Events in Cell Biology and Disease (1996) Chairperson

  • Matrix Biology (1997-2012) Board Member

  • Journal of Cell Biology (2001-present) Associate Editor

  • Journal of Cell Science (2006-present) Board Member

  • Biochemical Journal (2006-2008) Board Member

  • Biochemical Journal (2008-present) Editor

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