David Assis, MD

Assistant Professor of Medicine (Digestive Diseases)

Departments & Organizations

Internal Medicine: Adult Cystic Fibrosis Program | Digestive Diseases: Autoimmune and Cholestatic Liver Disease Program; Gastroenterology | Liver Center

Yale Medicine


Dr. Assis received his M.D. from Jefferson Medical College followed by internship and residency at Thomas Jefferson University Hospital in Philadelphia, where he was also Chief Resident. He completed training in gastroenterology and hepatology followed by transplant hepatology fellowships at Yale University.

His clinical and research interests are in autoimmune liver diseases. Specifically, he treats patients with autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis at his liver clinic. He also performs translational and basic research on autoimmune hepatitis using patient biospecimens in addition to work with animal models. He is investigating the link between the pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) and autoimmune hepatitis, and the effect of psychological stress on autoimmune hepatitis.

In addition, Dr. Assis is an active member of the Adult Cystic Fibrosis Program at Yale. In this role, he evaluates and treats patients with Cystic Fibrosis who have GI or liver complications of their disease. He also consults on patients from outside Yale's Cystic Fibrosis program who have these complications.

Education & Training

MD Jefferson Medical College (2005)
BS Messiah College (2001)
Fellowship Yale University School of Medicine
Fellowship Yale University School of Medicine
Residency Thomas Jefferson University Hospital
Internship Thomas Jefferson University, Hospital
Board Certification AB of Internal Medicine, Internal Medicine (2008, recertified: 2018)
Board Certification AB of Internal Medicine, Gastroenterology (2012)
Board Certification AB of Internal Medicine, Transpant Hepatology (2014, recertified: 2015)

Honors & Recognition

  • Rising Professional AwardAmerican Liver Foundation - Connecticut Chapter (2016)

  • 2014 Kushlan Junior Faculty AwardYale Section of Digestive Diseases (2014)

Professional Service

  • American Association for Study of Liver Diseases (2016 - Present) Secretary of the Special Interest Group in Cholestatic and Biliary Disease.

  • International Primary Sclerosing Cholangitis Study Group (2016 - Present) Co-leader of the Working Group on Clinical Trial Design.

  • North American Consortium for Autoimmune Liver Disease (2014 - Present) Steering Committee member of the Consortium, which is consists of a group of investigators from multiple academic medical centers throughout the United States and Canada who are committed to open collaboration to improve the study and treatment of patients with autoimmune liver diseases.

  • American Liver Foundation - Connecticut Chapter (2014 - Present) Board Member of Connecticut Chapter of the American Liver Foundation.

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Contact Info

David Assis, MD
Patient Care Locations
Yale Digestive DiseasesTemple Medical Center
40 Temple Street, Ste Suite 1A

New Haven, CT 06510
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Yale Digestive DiseasesYale Health Center
55 Lock Street

New Haven, CT 06511
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Yale Digestive DiseasesYale New Haven Hospital
20 York Street

New Haven, CT 06510
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Mailing Address
Digestive DiseasesPO Box 208019
New Haven, CT 06520-8019