Andrey Zinchuk, MD, MHS
Assistant Professor; Director, Advanced Apnea Management Program; Director, Yale Sleep Fellowship Didactic and Research Curriculum, Internal Medicine, PCCSM; Director, Upper Airway Neurostimulation Program; Section of Pulmonary, Critical Care and Sleep Medicine
Biography
Research & Publications
Patient Care
News
Locations
Appointments
Biography
After working as a chemical engineer, I completed my medical school training at University of Connecticut and have found the intersection between disciplines to be an exciting area for patient care and research. I have trained in internal medicine, neurology, pulmonary, critical care and sleep medicine and am now focused on caring for patients with sleep disorders and those who are critically ill.
Patient care: My goal is to provide the kind of care that I would want for my own family. I believe in taking the time to hear the patient and being a guide in their journey in health and illness. In the clinic, my focus is on caring for patients with sleep disorders and in particular, individuals with complex sleep disordered breathing.
Research: My aim is to improve the lives of people with sleep disordered breathing. My colleagues and I hope to do so by identifying subgroups (phenotypes) of sleep apnea patients with unique physiology, prognoses and treatment responsiveness, as well as through development of novel, effective and tolerable treatments.
Service: I am working to mitigate the consequences of Russia's war on the health of Ukrainian people. Along with other Yale colleagues with Ukrainian roots, we co-founded Doctors United for Ukraine, a non-profit organization focused on critical care, mental and women's health of vulnerable populations in Ukraine. Doctors United for Ukraine – Dwight Hall at Yale
Mentors: Klar Yaggi MD, MPH, Andrew Wellman, MD, PhD (Harvard), Scott Sands, PhD (Harvard), Nancy Redeker, RN, PhD (UCONN)
Education & Training
- MHSYale University (2018)
- Fellow, Sleep MedicineYale University (2017)
- Fellow, Pulmonary & Critical CareYale University (2016)
- Chief Medical ResidentBeth Israel Deaconess Medical Center and Boston Veterans Affairs Medical Center (2013)
- Resident, Internal MedicineBeth Israel Deaconess Medical Center, Harvard University (2012)
- Resident, NeurologyBeth Israel Deaconess Medical Center, Harvard University (2010)
- Intern, Internal MedicineBeth Israel Deaconess Medical Center, Harvard University (2009)
- MDUniversity of Connecticut (2008)
- BSLehigh University (2000)
Activities
- Sleep Clinic 2030: Big Data, Wearables and Deep Learning Change Sleep MedicineCreator and Chair of Symposium 2020Sleep Clinic 2030: Big Data, Wearables and Deep Learning Change Sleep Medicine
- Physiological Phenotypes of OSAVirtual meeting presentation 2020Physiological Phenotypes of OSA
- A. Zinchuk, H. K. Yaggi, J. Liang, J. Chu, S. Op de Beeck, C. Stepnowsky, D. Wellman, Y. Peker, S. A. Sands. Physiologic OSA Traits and CPAP Adherence Among Patients With Coronary Artery Disease And OSAVirtual oral presentation 20201. A. Zinchuk, H. K. Yaggi, J. Liang, J. Chu, S. Op de Beeck, C. Stepnowsky, D. Wellman, Y. Peker, S. A. Sands. Physiologic OSA Traits and CPAP Adherence Among Patients With Coronary Artery Disease And OSA
- A. Zinchuk, H. K. Yaggi, J. Liang, J. Chu, S. Op de Beeck, C. Stepnowsky, D. Wellman, Y. Peker, S. A. Sands. Physiologic Traits Predict Therapeutic Pressure Requirements and Residual Respiratory Events Among Patients with Coronary Artery Disease and Obstructive Sleep ApneaVirtual poster presentation 2020A. Zinchuk, H. K. Yaggi, J. Liang, J. Chu, S. Op de Beeck, C. Stepnowsky, D. Wellman, Y. Peker, S. A. Sands. Physiologic Traits Predict Therapeutic Pressure Requirements and Residual Respiratory Events Among Patients with Coronary Artery Disease and Obstructive Sleep Apnea
- Phenotypes of Sleep Apnea: Implications for Precision MedicineOsaka, Osaka, Japan 2019Phenotypes of Sleep Apnea: Implications for Precision Medicine
- Physiologic Subtypes of Obstructive Sleep Apnea” in course of “OSA Diagnosis and ManagementVancouver, BC, Canada 2019"Physiologic Subtypes of Obstructive Sleep Apnea” in course of “OSA Diagnosis and Management"
- Subjective data: questionnaires” panel discussion leader in “Sleep-circadian Informatics Data HarmonizationVancouver, BC, Canada 2019Subjective data: questionnaires” panel discussion leader in “Sleep-circadian Informatics Data Harmonization
- OSA Physiology and Personalized Medicine: Beyond the AHINorwalk, CT, United States 2019OSA Physiology and Personalized Medicine: Beyond the AHI
- A. Zinchuk, H.K. Yaggi, J. Concato, S. Jeon, D. Bravata, A. Wellman, S. Sands. “Low arousal threshold correlates with reduced continuous positive airway pressure use in non-obese individuals with obstructive sleep apnea and strokeDallas, TX, United States 2019A. Zinchuk, H.K. Yaggi, J. Concato, S. Jeon, D. Bravata, A. Wellman, S. Sands. “Low arousal threshold correlates with reduced continuous positive airway pressure use in non-obese individuals with obstructive sleep apnea and stroke, RaPID oral poster presentation
- Upper Airway Stimulation for Sleep Disordered BreathingSan Antonio, TX, United States 2019Co-Chair, “Upper Airway Stimulation for Sleep Disordered Breathing
- Clinical and Polysomnographic OSA PhenotypesSan Antonio, TX, United States 2019Clinical and Polysomnographic OSA Phenotypes
- A Look to the Future of Sleep. Use of Novel Technologies and Software AnalysisDallas, TX, United States 2019A Look to the Future of Sleep. Use of Novel Technologies and Software Analysis
- A. Zinchuk, H.K. Yaggi, J. Concato, A. Wellman, E. Smales, L. Hess, J. Denos, Y. Peker, S. Sands. Effect of arousal scoring on reliability of automated, non-invasive phenotyping of physiologic sleep apnea traits from polysomnographyDallas, TX, United States 2019A. Zinchuk, H.K. Yaggi, J. Concato, A. Wellman, E. Smales, L. Hess, J. Denos, Y. Peker, S. Sands. Effect of arousal scoring on reliability of automated, non-invasive phenotyping of physiologic sleep apnea traits from polysomnography
- B. Cade, J. Lee, S. Gharib, D. Gottlieb, K. He, D. Hillman, J. Liang, … A. Zinchuk, R. Saxena, S. Purcell, X. Zhu, S. Redline. Shared Genetic Architecture Between Sleep and Blood Pressure Traits in HumansDallas, TX, United States 20195. B. Cade, J. Lee, S. Gharib, D. Gottlieb, K. He, D. Hillman, J. Liang, … A. Zinchuk, R. Saxena, S. Purcell, X. Zhu, S. Redline. Shared Genetic Architecture Between Sleep and Blood Pressure Traits in Humans
- Sleep Apnea PhenotypesSpringfield, MA, United States 2018Sleep Apnea Phenotypes
- Clinical Implications of Sleep Apnea PhenotypesNew York, NY, United States 2018Clinical Implications of Sleep Apnea Phenotypes
- Polysomnographic Sleep Apnea PhenotypesSan Antonio, TX, United States 2018Polysomnographic Sleep Apnea Phenotypes
- Clinical Sleep Apnea Phenotypes and Cardiovascular DiseaseSan Diego, CA, United States 2018Clinical Sleep Apnea Phenotypes and Cardiovascular Disease
- Novel physiologic predictors of adherence to PAP: NICEPAP studyBoston, MA, United States 2018Novel physiologic predictors of adherence to PAP: NICEPAP study
- Patient-Centered Outcomes in Sleep-Disordered BreathingBaltimore, MD, United States 2018Patient-Centered Outcomes in Sleep-Disordered Breathing
- Zinchuk, A., Koo, B., Jeon, S., Yaggi, H.K.. High Frequency of PLMS is Associated with Increased Risk Of Incident Cardiovascular Events and Death Among OSA PatientsBaltimore, MD, United States 2018Zinchuk, A., Koo, B., Jeon, S., Yaggi, H.K.. High Frequency of PLMS is Associated with Increased Risk Of Incident Cardiovascular Events and Death Among OSA Patients
- Trivedi V, Zinchuk A, Qin L, Bravata DM, Strohl KP, Selim BJ, Yaggi HK. A Composite Model of Commonly Derived Polysomnographic Variables Predicts Risk of Cardiovascular Outcomes Better Than the Apnea Hypopnea Index AloneBaltimore, MD, United States 2018Trivedi V, Zinchuk A, Qin L, Bravata DM, Strohl KP, Selim BJ, Yaggi HK. A Composite Model of Commonly Derived Polysomnographic Variables Predicts Risk of Cardiovascular Outcomes Better Than the Apnea Hypopnea Index Alone
- Shoajee, A., Yaggi, K., Siner, J., Zang, W., Zinchuk, A. Obstructive sleep apnea increases the risk of diastolic heart failure: results of a large population studySan Diego, CA, United States 2018Shoajee, A., Yaggi, K., Siner, J., Zang, W., Zinchuk, A. “Obstructive sleep apnea increases the risk of diastolic heart failure: results of a large population study
- Polysomnographic phenotypes in obstructive sleep apnoea and their cardiovascular implicationsLondon, England, United Kingdom 2017Polysomnographic phenotypes in obstructive sleep apnoea and their cardiovascular implications
- Continuous vs. Auto-Positive Airway Pressure: Does It MatterToronto, ON, Canada 2017Continuous vs. Auto-Positive Airway Pressure: Does It Matter
- Phenotyping in OSA: Leveraging Physiology for Patient OutcomesTucson, AZ, United States 2017Phenotyping in OSA: Leveraging Physiology for Patient Outcomes
- Phenotyping in OSA: Approaches and ExamplesBoston, MA, United States 2017Phenotyping in OSA: Approaches and Examples
- Zinchuk, A., Edwards, B., Jeon, S., Yaggi, K. Arousal threshold, obesity, age and race predict CPAP use among U.S. Veterans with OSABoston, MA, United States 2017Zinchuk, A., Edwards, B., Jeon, S., Yaggi, K. Arousal threshold, obesity, age and race predict CPAP use among U.S. Veterans with OSA
- Brady, V., Zinchuk, A., Possick, J. TB or not TB: That is the QuestionWashington, DC, United States 2017Brady, V., Zinchuk, A., Possick, J. TB or not TB: That is the Question
- Zinchuk, A., Yaggi, H., Thomas, R., Redeker, N. ECG-derived spectrogram measures of sleep quality, insomnia and functional outcomes among patients with heart failureDenver, CO, United States 2016Zinchuk, A., Yaggi, H., Thomas, R., Redeker, N. ECG-derived spectrogram measures of sleep quality, insomnia and functional outcomes among patients with heart failure
- Zinchuk, A., Koo, B., Jeon, S., Redeker, N., Concato, J., Yaggi, H. Clinically Relevant Phenotypes of Obstructive Sleep ApneaSan Francisco, CA, United States 2016Zinchuk, A., Koo, B., Jeon, S., Redeker, N., Concato, J., Yaggi, H. Clinically Relevant Phenotypes of Obstructive Sleep Apnea
- Zinchuk, A., Bravata, D., Shah, N., Koo, B., Won, C., Qin, L., Jeon, S., Redeker, N., Mohsenin, V., Selim, M., Kingman, S., Concato, J., Yaggi, H. The Apnea-CV Risk Score: A Simple Prognostic Tool for Cardiovascular Events and Mortality Among Patients with Sleep-Disordered BreathingDenver, CO, United States 2015Zinchuk, A., Bravata, D., Shah, N., Koo, B., Won, C., Qin, L., Jeon, S., Redeker, N., Mohsenin, V., Selim, M., Kingman, S., Concato, J., Yaggi, H. The Apnea-CV Risk Score: A Simple Prognostic Tool for Cardiovascular Events and Mortality Among Patients with Sleep-Disordered Breathing
- Bazan I, Zinchuk A, Mohsenin V, Homer R, Fares W. Unique Cause Of A Lung Mass In A Patient With AIDSDenver, CO, United States 2015Bazan I, Zinchuk A, Mohsenin V, Homer R, Fares W. Unique Cause Of A Lung Mass In A Patient With AIDS
- Zinchuk, A. A Novel Sleep Apnea Treatment: A Wearable Transcranial Magnetic Stimulation DeviceNew Haven, CT, United States 2014Zinchuk, A. A Novel Sleep Apnea Treatment: A Wearable Transcranial Magnetic Stimulation Device
- Zinchuk, A., Boosalis, V., M.D., Brahma, P., Saukkonen, J. Simultaneous mantle cell lymphoma and undifferentiated carcinoma presenting as pleural studding and effusionChicago, IL, United States 2013Zinchuk, A., Boosalis, V., M.D., Brahma, P., Saukkonen, J. Simultaneous mantle cell lymphoma and undifferentiated carcinoma presenting as pleural studding and effusion
- Zinchuk, A., Wood, C., Mietus, J., Thomas, R. ECG-based Cardiopulmonary Coupling Sleep Indices as Markers for the Impact of Obstructive Sleep Apnea on NeurocognitionBoston, MA, United States 2012Zinchuk, A., Wood, C., Mietus, J., Thomas, R. ECG-based Cardiopulmonary Coupling Sleep Indices as Markers for the Impact of Obstructive Sleep Apnea on Neurocognition
- Impact of the Chornobyl Disaster Perceptions on the Reproductive Health of Ukrainian WomenAmsterdam, NH, Netherlands 2007Impact of the Chornobyl Disaster Perceptions on the Reproductive Health of Ukrainian Women
- Zinchuk, A., Schensul, S., Bogatyryova, H., Gnateyko, O. Impact of the Chornobyl Disaster Perceptions on the Reproductive Health of Ukrainian WomenAmsterdam, NH, Netherlands 2007Zinchuk, A., Schensul, S., Bogatyryova, H., Gnateyko, O. Impact of the Chornobyl Disaster Perceptions on the Reproductive Health of Ukrainian Women
Honors & Recognition
| Award | Awarding Organization | Date |
|---|---|---|
| Top Author for 2020 Review Articles, recognized for article: "Phenotypic Subtypes of OSA: A Challenge and Opportunity for Precision Medicine" | CHEST Journal | 2021 |
| Most cited articles since 2017 for article “Phenotypes in obstructive sleep apnea: A definition, examples and evolution of approaches” | Sleep Medicine Reviews Journal (highest impact journal devoted to Sleep Medicine) | 2020 |
| Top-10 Paper in Sleep Medicine, "Cardiovascular phenotypes and their cardiovascular implication in Obstructive Sleep Apnoea.” | American Academy of Sleep Medicine | 2018 |
| Outstanding Early Investigator Award | Sleep Research Society | 2018 |
| Parker B. Francis Fellowship Career Development Award | Francis Family Foundation | 2018 |
| Highlighted paper, “Cardiovascular phenotypes and their cardiovascular implication in Obstructive Sleep Apnoea” | British Thoracic Society, London | 2017 |
| Sleep Research Society Trainee Merit Based Award | Associated Professional Sleep Societies Annual Meeting, Boston MA | 2017 |
| Award Winner and Grant Recipient for Clinical Research | 12th Annual Respiratory Disease Young Investigators Forum | 2016 |
| Fellowship in Clinical Research Grant Award | Robert E. Leet and Clara Guthrie Patterson Trust | 2016 |
| Yale Center for Clinical Investigation and Center for Biomedical and Interventional Technology Emerging Core Award | Yale University | 2014 |
| The James H. Foster, M.D. Teaching Award, Excellence of Medical Student Education | University of Connecticut School of Medicine, Farmington, CT | 2008 |
| Winner, Global Health Project Competition | 15th Annual Global Health Education Consortium Conference, Toronto | 2006 |
| University of Connecticut Research Day Award | University of Connecticut, Farmington CT | 2006 |
| Presidential Scholar Award | Lehigh University | 2001 |
| Phi Beta Kappa, Tau Beta Pi--Engineering | Phi Eta Sigma Honor Societies | 1996 |
Professional Service
| Organization | Role | Date |
|---|---|---|
| Yale School of Medicine Physician Associate Thesis Readers | Member | 2020 - Present |
| Yale School of Medicine/Yale New Haven Hospital Internal Medicine Residency Mentor-Advisor-Coach committee | Member | 2020 - Present |
| Yale New Haven Hospital and Yale School of Medicine Focus group on Physician Burnout and Resilience | Member | 2019 - Present |
| Principles and Practice of Sleep Medicine (Seventh Edition), the authoritative reference book for sleep researchers and practitioners, Co-Editor for Sleep Disordered Breathing Section | Associate Editor | 2019 - Present |
| American Thoracic Society, Sleep Respiratory Neurobiology Program Committee, Scientific Session Co-chair and Poster Discussion Facilitator | Co-Chair | 2018 - 2020 |
| Yale University and Yale New Haven Hospital, Advanced Apnea Management Program | Director | 2018 - Present |
| Yale Sleep Fellowship Program Clinical Competency Committee | Member | 2017 - Present |
| Yale University, Sleep Fellowship Didactic and Research Educational Curriculum | Director | 2017 - Present |
| American Academy of Sleep Medicine (SLEEP/APSS), Scientific Session Co-chair and Discussion Facilitator | Co-Chair | 2017 - Present |
| Sleep Research Society | Member | 2016 - Present |
| American Academy of Sleep Medicine (SLEEP/APSS), VA Sleep Clinical and Research Network | Member | 2015 - 2019 |
| American Thoracic Society, Sleep Respiratory Neurobiology Education and Web Committee | Committee Member | 2015 - 2018 |
| American Thoracic Society | Member | 2013 - Present |
| American College of Chest Physicians | Member | 2013 - Present |
| Guilford Center for Children | Volunteer | 2013 - Present |
| Guilford Free Public Library | Volunteer | 2013 - Present |
| American Journal of Respiratory and Critical Care Medicine, Annals of American Thoracic Society, CHEST, Journal of Clinical Sleep Medicine, Sleep and Breathing, Heart & Lung - The Journal of Acute and Critical Care, SLEEP, Sleep Medicine Reviews | Reviewer | 2013 - Present |
| American Academy of Sleep Medicine (SLEEP/APSS) | Member | 2011 - Present |
| Ukrainian Medical Association of North America | Member | 2008 - Present |