Albert Sinusas, MD

Professor of Medicine (Cardiology); Director, Translational Research Imaging Center; Director, Cardiovascular Imaging

Research Interests

Cardiology; Cardiovascular System; Echocardiography; Magnetic Resonance Imaging; Tomography, Emission-Computed, Single-Photon; Positron-Emission Tomography; Myocardial Perfusion Imaging; Translational Medical Research

Research Organizations

Internal Medicine: Cardiovascular Medicine: Yale Translational Research Imaging Center (Y-TRIC)

Bioimaging Sciences

Clinical Radiology

Vascular Biology and Therapeutics Program

Office of Cooperative Research

Research Summary

My research is directed at development of noninvasive imaging approaches for the assessment of myocardial viability, angiogenesis, and post–infarction remodeling. This translational research employs the 3–D modalities of SPECT, PET, echocardiography and MR imaging for assessment of regional myocardial perfusion, function and metabolism, in an animal physiology laboratory, employing large and small animal models of myocardial ischemia and infarction, and peripheral arterial disease. My laboratory is currently focused on targeted molecular imaging, developing non–invasive nuclear imaging strategies for identifying the hypoxic stimulus for angiogenesis, and targeted imaging of selected integrins previously established to modulate the angiogenic process, and evaluation of the role of matrix metalloproteinases on post–infarction remodeling. The investigation of these biological processes involves, in vitro cellular and whole heart preparations, as well as ex vivo and in vivo imaging in both small and large animal models, using dedicated high–resolution and real–time 3D ultrasound imaging, hybrid SPECT–CT and PET–CT imaging, cardiac MR imaging, and fluorescent imaging systems.

Specialized Terms: Advanced cardiovascular and molecular imaging

Selected Publications

Full List of PubMed Publications

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Contact Info

Albert Sinusas, MD
Patient Care Locations
Yale CardiologyYale New Haven Shoreline Medical Center
111 Goose Lane, Ste 2nd Floor

Guilford, CT 06437
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Yale Nuclear CardiologyYale New Haven Hospital
20 York Street

New Haven, CT 06510
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Mailing Address
Internal MedicinePO Box 208056
333 Cedar Street

New Haven, CT 06520-8056

Curriculum Vitae

Yale Translational Research Imaging Center (Y-TRIC)