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Yale Department of Internal Medicine Celebrates Top Female Scientists

December 05, 2022
by Elisabeth Reitman, Julie Parry and Abigail Davis

Last month, Research.com published the Best Female Scientists in 2022. The results were based on a ranking system which measures the impact of a researcher’s publications by combining the number of papers they have published and how often they are cited by other papers.

623 U.S.-based researchers appeared in list with following three women representing the Yale Department of Internal Medicine.

Alexandra J. Lansky, MD

Alexandra J. Lansky, MD, is professor of medicine in Cardiology at the Yale School of Medicine (YSM) and director of the Yale Heart and Vascular Clinical Research Program. Her research focuses on the clinical outcomes of patients undergoing minimally invasive cardiovascular interventions, as well as evaluating the safety and effectiveness of novel medical devices, with a strong interest in sex-based outcomes. Examples of her trial leadership include EMPOWER CAD, which will assess the safety and effectiveness of IntraVascular Lithotripsy (IVL) in the first all female patient interventional study and the landmark FREEDOM Trial, which demonstrated the benefits of bypass surgery in patients with diabetes. In 2004, she led the first American Heart Association sex-specific statement on revascularization and in 2017 she led the first consensus on defining neurologic endpoints in cardiovascular trials. Dr Lansky is the inaugural Editor-in-Chief of the Journal of the Society of Cardiac Angiography and Intervention (JSCAI).

Her most cited work include:

  • Clinical end points in coronary stent trials: A case for standardized definitions
  • A prospective natural-history study of coronary atherosclerosis
  • A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: Development and initial validation

Amy C. Justice, MD, PhD

Amy C. Justice, MD, PhD, C.N.H. Long Professor of Medicine (General Medicine), YSM, and professor of public health (health policy), Yale School of Public Health, is a clinical epidemiologist. Justice has devoted the last two decades to developing large national cohorts based on data from the VA Healthcare System’s electronic medical record (EMR). She is the principal investigator on the Veterans Aging Cohort Study (VACS), which compares outcomes among veterans aging with and without HIV infection. Her understanding of the EMR has also enabled her to conduct instrumental research on HIV-associated cancers, substance use, and COVID-19. Justice’s work has been critical in furthering the Million Veteran Program and a VA collaboration with the Department of Energy applying artificial intelligence and high-performance computing.

Her most cited work include:

  • Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies.
  • Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies
  • Effect of early versus deferred antiretroviral therapy for HIV on survival.

Mary Tinetti, MD

The current research and clinical focus of Mary Tinetti, MD, Gladys Phillips Crofoot Professor of Medicine (Geriatrics) and Public Health is on clinical decision-making for older adults with multiple health conditions. She measures the net benefit and harms of commonly used medications, and studies the importance of cross-disease universal health outcomes. Tinetti leads Patient Priorities Care, a national effort to align clinical care and decision-making with the specific health priorities of older adults with multiple conditions. Her previous research involved the identification of risk factors for, and prevention of, falls in older adults.

Her most cited work include:

  • Risk factors for falls among elderly persons living in the community.
  • Performance-oriented assessment of mobility problems in elderly patients
  • A multifactorial intervention to reduce the risk of falling among elderly people living in the community.

The Department of Internal Medicine at Yale is among the nation's premier departments, bringing together an elite cadre of clinicians, investigators, educators, and staff in one of the world's top medical schools. To learn more, visit Internal Medicine.

Submitted by Julie Parry on December 04, 2022