Yale and Mayo Clinic Awarded FDA Grant to Study Opioid Prescribing and Use
Yale University and Mayo Clinic have been awarded a grant for up to $5.3 million over two years by the U.S. Food and Drug Administration (FDA) to study patients’ experiences with pain and use of opioids prescribed for acute pain. This project is part of the Center of Excellence in Regulatory Science and Innovation (CERSI), a joint effort between Yale, Mayo Clinic, and the FDA. The study will be conducted in collaboration with Regional Health of Rapid City, S.D., and University of Alabama at Birmingham (UAB).
Meet Yale Internal Medicine: Sarwat Chaudhry, MD, Associate Professor of Medicine (General Internal Medicine); Co-Director, National Clinician Scholars Program; and Vice-Chair, Dean’s Faculty Advisory Council.
As part of our “Meet Yale Internal Medicine” series, today’s featured physician is Sarwat Chaudhry, MD, associate professor of medicine (general internal medicine); co-director, National Clinician Scholars Program; and vice-chair, Dean’s Faculty Advisory Council.
Krystal and Nunez-Smith Are Honored by Association for Clinical and Translational Science
John H. Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research, chair and professor of psychiatry, and professor of neuroscience; and Marcella Nunez-Smith, MD, MHS, associate professor of medicine (general medicine) and of epidemiology (chronic diseases), have been chosen for awards by the Association for Clinical and Translational Science.
Patrick O’Connor to Chair National Clinician Scholars Program Board of Directors
Patrick G. O’Connor, MD, MPH, Dan Adams and Amanda Adams Professor of General Medicine and chief of general internal medicine, has been elected chair of the National Clinician Scholars Program Board of Directors. His three-year term began on January 1.
Krumholz, Spatz receive funding to develop new 24/7 blood pressure monitor
The National Institute of Biomedical Imaging and Bioengineering has awarded a $1.2 million, four-year grant to investigators at Texas A&M University and Yale University for the development of a wrist-worn, cuffless blood pressure monitoring system.
Medical faculty elected to the American Society for Clinical Investigation
Drs. Daniel Greif, Cary Gross, Chirag Parikh, and Joseph Ross of Yale School of Medicine have been elected to the American Society for Clinical Investigation (ASCI). One of the nation’s oldest and most prestigious medical honor societies, ASCI supports the work of top physician-scientists whose research improves human health.
Most studies misuse data set, researchers find
A team of researchers, including a professor and a postdoctoral researcher at Yale, recently published a paper with troubling findings: The vast majority of a set of studies conducted with data from a widely used public data set are not meeting required methodological standards. According to the study, which was published in the Nov. 28 issue of JAMA, 102 of 120 studies — selected at random and intended as a representative sample of the 1,084 studies published using an open-source database in 2015–16 — did not adhere to one or more required research practices.
Yale experts selected to conduct medical device surveillance research
Two projects conducted by Yale School of Medicine faculty have been selected as Demonstration Projects by NEST, the National Evaluation System for Health Technology, which was established by the Medical Device Innovation Consortium and funded by FDA.
Pushing Hospitals To Reduce Readmissions Hasn't Increased Deaths
Too often, people return home from the hospital only to find themselves heading back soon after. Sometimes the need arises because, despite the best care, it is difficult to slow the progression of disease. But other times, it's because we in the health care system fail to communicate, coordinate and orchestrate the care that people need to successfully make the transition from hospital to home.Source: NPR Shots
Heart study finds faulty link between biomarkers and clinical outcomes
Surrogate endpoints (biomarkers), which are routinely used in clinical research to test new drugs, should not be trusted as the ultimate measure to approve new health interventions in cardiovascular medicine, according to a recent study by Yale School of Medicine researchers in JAMA.
Seeking better health: Yale and New Haven
In the early 1970s, Maria Melendez, recently arrived from Puerto Rico, saw that there were no Spanish-speaking doctors serving her new neighborhood of Fair Haven. With others in the community as well as local groups, she launched a campaign that led first to nursing visits and then to the establishment of the Fair Haven Community Health Center.Source: Yale Medicine
Yale Study: Minority Breast Cancer Patients Less Likely To Have Genetic Test
A genetic test that helps doctors determine how best to treat breast cancer—and whether chemotherapy is likely to help—is significantly more likely to be administered to white women than blacks or Hispanics, a Yale study has found.Source: Connecticut Health I-Team
Trump wants faster FDA action, but 1 in 3 drugs have safety issues after approval
President Trump wants the Food and Drug Administration to approve drugs faster, but researchers at the Yale School of Medicine found that nearly a third of medications that reached the market from 2001 through 2010 had major safety issues years after they became widely available to patients.Source: STAT
FDA approves drugs more quickly than peer agency in Europe
The U.S. Food and Drug Administration (FDA) reviews and approves new medicines in a shorter timeframe than its peer agency in Europe, the European Medicines Agency (EMA), says a Yale researcher. This finding comes at a time when the FDA is under renewed pressure to streamline and speed up its approval process, and provides data to inform ongoing policy discussions.
More than 8 million children could face higher insurance costs without CHIP
More than 8 million children enrolled in the Children’s Health Insurance Program (CHIP) could be at risk of losing coverage if federal funding for the program is not extended this year. Children with chronic conditions are most vulnerable, and their families could face substantial cost increases if they lose CHIP coverage and need to shift their insurance to a Marketplace plan, according to a Yale study.
The immigration ban threatens the health of patients and the public
We took an oath in medical school. Earnestly, in short white coats, we acknowledged our “special obligations to all [our] fellow human beings” and our commitment to care for those who sought our help. And now, as full-fledged physicians, we find our ability to fulfill this special obligation obstructed. The Trump administration’s immigration policies have shaken up families and communities. As the first executive order (EO) barring people from seven majority-Muslim nations from entering the United States. is under scrutiny in the courts, a second, similar ban has also been halted by legal challenges. Outside the courtroom, however, Immigration and Customs Enforcement (ICE) raids are occurring with increasing intensity and breadth.Source: Medium.com
Racial Disparities in Genetic Testing of Women With Breast Cancer
MedicalResearch.com Interview with: Cary P. Gross, MD Section of General Internal Medicine Yale University School of Medicine New Haven, CT MedicalResearch.com: What is the background for this study? What are the main findings? Response: Prior work has demonstrated racial and socioeconomic disparities in breast cancer diagnosis, treatment, and outcomes. As the oncology field has progressed over the past decade, the use of genetic testing to guide treatment decisions is one of the most exciting new developments.Source: Medical Research