Geneticist Sidi Chen Receives Large Award Which Will Further His Breast Cancer Work
This Department of Defense award goes to the “best and brightest in their fields,” and recognizes “creative and innovative individuals.” Investigators are chosen for their ability “to go beyond conventional thinking” in their respective areas of expertise.
Yale Scientists Help Immune System Find Hidden Cancer Cells
Cancer cells are masters at avoiding detection, but a new system developed by Yale Cancer Center scientists can make them stand out from the crowd and help the immune system spot and eliminate tumors that other forms of immunotherapies might miss, the researchers report Oct. 14 in the journal Nature Immunology.
Clinical trials take innovative approach
Since their arrivals at Yale within the past six years, Joseph Paul Eder, MD, and Patricia LoRusso, DO, have overseen a sharp increase in the number of clinical trials conducted by the Phase I Program at Yale Cancer Center. Bench investigators and the clinicians who design and conduct early-phase trials interact regularly, each sharing knowledge with the other that both strengthens the basic science and brings new discoveries to patients more quickly and effectively.
Breast cancer test helps determine who will benefit from long-term therapy
Women with a common form of breast cancer can receive better advice about whether to undergo long-term therapy because of a new genetic test, according to a Yale School of Medicine doctor. Dr. Tara Sanft, medical director of the survivorship program at the Yale Cancer Center and a breast cancer oncologist, said the test helps to predict who will benefit by undergoing anti-estrogen therapy for more than the standard five years.Source: New Haven Register
American Cancer Society Approves New Research and Training Grants at Yale University
The American Cancer Society (ACS), the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding for three new research grants totaling over $1.7 million to investigators at Yale University. These grants are among 11 new projects in effect across New England as of January 1, 2017 totaling more than $4.4 million dollars.
Large Gene Network Required to Predict Response to HER2-Targeted Therapy
It is unlikely that any single gene can predict response to targeted therapy for patients with HER2-positive breast cancer, new findings from a study suggest. Instead, gene networks— specifically those involving PI3 kinase (PI3K)—may provide a clearer picture of patient outcomes.Source: OncLive
Dr. Raman Nelakanti Awarded the 2023 Slayman Prize in Genetics
The Carolyn Slayman prize, awarded each year by the Department of Genetics, recognizes not only achievement in scientific research but also exceptional contributions to the scientific community. This year’s recipient is Dr. Raman Nelakanti, a geneticist who recently obtained his MD-PhD from the School of Medicine.
How genetics determine our life choices
It has been 20 years since the Human Genome Project was "completed". But it quickly became apparent that the efforts to sequence and map the human "book of life" was only just the beginning. Far from closing the question of what makes our bodies tick and why they do so differently, research on the human genome has revealed a far more complex picture than anyone could have imagined. We may not realize it, but it appears that many routine aspects of our daily lives might be partially driven by our genome.Source: BBC.com
Researchers explore the role of cellular plasticity in cancer
A recently published Yale study explored how cancer cell plasticity — which refers to the ability of cells to adapt their phenotypes in response to environmental signals without undergoing genetic alterations — might impact the development, progression and treatment of cancer.Source: Yale Daily News
Multidisciplinary COPPER Center Brings a Public Health Lens to Cancer Care
Studying cancer treatment outcomes is the mission of the Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, a collaborative effort of the Yale Cancer Center and the Schools of Medicine and Public Health.Source: Yale Public Health magazine