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Pilot Feasibility Grants

2021-2022 Applications


The NIH/NIDDK P30 Liver Center grant provides for the annual submission of pilot projects (up to $40,000 direct costs each) from both Liver Center and non-Liver Center investigators.

The purposes of the pilots are to fund new initiatives, not ongoing research, and to support new investigators to pursue liver related research that should lead to future R01-type funding or other support. Projects utilizing Core Facilities and supporting young investigators or applying new methodologies or approaches to the study of liver pathophysiology are given priority.

Investigators should meet one of the following criteria, in order of priority:

  1. Senior fellows or junior faculty at Yale, currently not funded by NIH grants and in need of funds to help prepare for R01-type applications.
  2. Established University investigators not currently funded for work related to the Center’s focus on liver related research, but who wish to apply their areas of expertise to subjects of Center interest.
  3. Funded Center investigators who wish to pursue a project that is different from their current focus of interest, and who needs to develop preliminary data to apply for new R01-type funding.

Pilot grants will undergo two levels of review: first from Center executive committee and then from our External Advisory Board. The Board will convene at Yale in July or August to determine a priority score for each request and can approve or disapprove the project or modify the budget. No pilot projects can be submitted for more than two consecutive years.

All current pilot project recipients must follow the same guidelines to request a second year of funding.

Important Dates

Please note the following dates on your calendar:

Friday, April 16, 2021

Deadline for submission of Letter of Intent (one electronic copy) emailed to Christine Abu-Hanna by 5:00pm.

The letter of intent must include the following:

  1. Academic position, VISA status and future scientific plans regarding liver-related research
  2. Title of pilot project and
  3. A sentence as to the applicability of the pilot project to the Liver Center. Projects must make use of the Center’s facilities.

Upon Letter of Intent review by the Executive Committee, applicants will be notified whether they can submit a full application.

Friday, May 14, 2021

Deadline for submission of full applications (one electronic copy) emailed to Christine Abu-Hanna by 5:00pm. This should include all documents listed below. Due to pilot projects being internally funded, a TranSum and Office of Sponsored Projects approval/signature is not required.

Friday, May 28, 2021

Internal reviews of most competitive applications are returned to investigators for revisions.

Friday, June 18, 2021

Receipt of revised application deadline (one electronic copy) emailed to Christine Abu-Hanna by 5:00pm.

July or August 2021

External Advisory Board meets to make final decisions on awards. Applicants will be expected to present their pilot project to the Board on this date (approximately 15 minutes).

September 1, 2021

Approved projects will begin funding.

Format of applications

The general format of the NIH research project applications on fillable individual PHS 398 forms Rev. 3/20 approved through 03/28/2023 must be used to request pilot funding. Please only use forms listed in the instructions and submit in the order listed. If using the PDF forms, Adobe Acrobat Professional software is required to save/edit your application on the forms required when submitting your application. Instructions for grant applications can be found on the left hand side of this page. Please only include the forms listed.


If you have any questions, please contact Christine Abu-Hanna by email or 203-785-5610.