Project NEW HOPE

Project NEW HOPE was a double-blinded placebo controlled RCT of XR NTX among HIV+ prisoners with opioid dependence who were transitioning from the prison to the community setting. HIV treatment (HIV-1 RNA levels, CD4 count), substance abuse treatment (time to relapse to opioid use, percent of days using opioids, percent of days abstinent from opioids, addiction severity), adverse side effects, and HIV risk behavior (sexual and drug-related risks) outcomes were assessed. This project was conducted in New Haven, Hartford, and Springfield in collaboration with Baystate Medical Center.

Bio Profile

Sandra Ann Springer, MD

Principal Investigator

Associate Professor of Medicine (AIDS) and Associate Clinical Professor of Nursing

Director, Infectious Disease Outpatient Clinic, Veterans Administration Healthcare Services, Newington

Sandra Springer, MD is an Associate Professor of Medicine in the Department of Internal Medicine, Section of Infectious Diseases at the Yale School of Medicine. She is also the Director of the Infectious Disease (ID) Clinic at the Newington site of t and an Attending ID physician at the West Haven site of the VA Connecticut Healthcare System (VACHS). She is board-Certified in Internal Medicine, Infectious Diseases and Addiction Medicine. She has significant clinical and research experience with...

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Funding provided by:
National Institute on Drug Abuse 

Project Period:
September 1, 2010 – August 31, 2015 

Link to Report:
Project New Hope at