New Research Sheds Light on Equitable Treatment Options for Pediatric Patients with Sickle Cell Disease
A new study led by Yale Cancer Center researchers at Yale School of Medicine for the first time analyzed the cost effectiveness of allotransplantation therapy and gene therapy to help determine equitable treatment options for this historically marginalized pediatric patient population in the United States.
Yale Cancer Center Physicians Bring Myeloma Message to Hamden’s Newhall Neighborhood
Doctors and researchers still are not sure what causes myeloma, a rare cancer of the white blood cells that initially shows few symptoms, but they do know that 20 percent of myeloma cases are detected in Black Americans – and that the number is rising. That is why members of the Yale Myeloma team went to Hamden’s Newhall neighborhood on November 30 for, “Understanding Myeloma: A Community Event.”
Phase 3 Results Offer Hope for Patients With Myelodysplastic Syndromes
Senior author of the study and Yale Cancer Center expert Amer Zeidan , MBBS, says the results showed that imetelstat, a first-in-class telomerase inhibitor, leads to durable red blood cell transfusion independence and a significant improvement in anemia in heavily transfused lower-risk MDS patients.
Yale Cancer Center Experts Present New Research at Hematology Annual Meeting
Physicians and scientists from Yale Cancer Center, part of Yale School of Medicine, will present new research at the 65th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego, Calif., from December 9 to 12.
Dr. George Goshua Named Finalist for NOMIS & Science Young Explorer Award
In recognition of his innovation and visionary research, George Goshua, MD, MSc, Assistant Professor of Medicine (Hematology), has been recognized as a finalist for the NOMIS & Science Young Explorer Award. The award acknowledges three young and creative researchers across the globe who take bold risks to ask fundamental questions at the intersection of life and social sciences and who have made significant advances in applying techniques developed in one domain to address questions in another.
How a Time Out Can Help Address Bias
To counter the sometimes-deadly effects of bias in healthcare, hospital executive Gina Calder, Dr. Cecelia Calhoun, and other leaders in the field developed a tool to help teams spot and address bias in real time. The Bias Time Out draws on a system that has successfully reduced other kinds of medical errors.Source: Yale Insights
How PCPs can improve care for their transgender patients
In medical settings, transgender patients often must decide between facing the risks associated with transphobia and those associated with clinicians not having all possibly relevant information, according to an expert. “Transgender people experience mistreatment in health care encounters that can include harassment, assault and denial of care,” Ash B. Alpert, MD, MFA, lead study author and an instructor of medicine at the Yale School of Medicine division of hematology, and colleagues wrote in Annals of Family Medicine. “The specific experiences of transgender people when clinicians learn they are transgender and the impact of these experiences on patients’ information sharing remain largely unexplored.”Source: Healio
The Impact of Violence on Cancer Risk Factors for Marginalized Populations
Host, Dr. Catherine Cerulli is joined by her guests, Ash B. Alpert, MD, MFA, and Sabrina Jamileh Sayegh. Dr. Alpert and Sabrina explore the mechanisms by which violence plays a role in social determinants of health and how violence can contribute to cancer and/or cancer risk factors. Dr. Alpert explains that there are 4 major ways violence can lead to cancer and/or cancer risk factors including: 1) increased stress, otherwise known as allostatic load, which can lead to a higher risk of cancer through inflammatory pathways, 2) increased exposure to viruses including HPV, HIV and hepatitis for those exposed to sexual violence, 3) increased distress which can lead to increased substance use which can increase the risk of certain cancers including lung and liver cancer, and 4) increased mental distress and illness, which is linked to increased mortality for people living with cancer.Source: The Transform Center
Dr. Amer Zeidan Highlights Key Implications of the COMMANDS Trial in Lower-Risk MDS
Drs. Garcia-Manero and Zeidan discuss the significance of efficacy and safety data from the COMMANDS trial in myelodysplastic syndrome, takeaways from the subgroup analyses, and expectations around treatment sequencing in the lower-risk population.Source: OncLive
Stigma, Even Harm Common When Transgender People Meet With Doctors
Transgender people have a tough time receiving adequate medical care due to issues like voyeurism, being treated as abnormal and even being denied care due to their gender identity, a new study finds. “After clinicians learn that patients are trans, usually transgender people feel that their care gets worse and not better,” said study author Dr. Ash Alpert (pronouns: they/them). “A number of people in the study talked about how people started misgendering them after they learned that they were transgender instead of getting their pronouns right.” These medical experiences left the study participants stuck between choosing to reveal their gender identity and face transphobia or withholding their gender identity and consequently receiving ineffective medical care. They also discussed the fact that improving the safety of transgender people in the medical system is complicated due to the medical field being “inherently violent or stigmatizing of transgender people.”Source: USNews
Introducing the Internal Medicine 2021-2022 Annual Report
In the new report, there are updates from our clinical programs, research endeavors, our work on diversity, equity, and inclusion, and educational programs. Our faculty members were honored for their educational excellence. Research initiatives at Yale received applause on the national and international stages. This book highlights all that we have accomplished together this past year…