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Research

Federally-funded research includes observational studies and randomized clinical trials of addiction treatment designed to facilitate the dissemination of effective strategies from specialty to primary care, Emergency Department and HIV clinical sites. Yale Addiction Medicine also conducts research at the interface of pain and addiction and substance use prevention. Faculty have ongoing projects in a variety of realms including quality improvement, community engaged research in addition to the partial list of projects below:

  • The Veterans Aging Cohort Study (VACS) is a prospective, observational cohort study of HIV- positive and an age/race/site matched control group of HIV- negative veterans in care in the United States. The study's aim is to understand the role of comorbid medical and psychiatric disease in determining clinical outcomes in HIV infection. It is funded primarily by the National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health. The study has a special focus on the role of alcohol use and alcohol use disorder in determining clinical outcomes.


  • The Yale Center for Health & Learning Games develops and evaluates videogame-based interventions with the goal of reducing risk (including substance use and smoking) and promoting healthy behaviors, social good and education. Its multidisciplinary team integrates established behavioral change theories into our interventions to create healthier, safer lives for our players. We aim to foster risk awareness, well-being, and social intelligence with high levels of engagement, fidelity, and impact. We use rigorous scientific methods and metrics to develop and evaluate our video game technology.



  • We have developed behavioral and medication treatments for patients presenting to the Emergency Department who use tobacco and engage in unhealthy alcohol and drug use. This area is of particular significance to Emergency Medicine as substance use problems are a leading cause of preventable illness and injury, and represent a substantial portion of the 140 million Emergency Department visits each year. An innovative new line of research at the Yale Department of Emergency Medicine focuses on the development of Emergency Department-initiated screening, treatment initiation and referral (STIR).
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