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Yale Tissue Regeneration and Fibrosis Program
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Publications

Recent one hundred publications from Yale faculty on injury, repair, and fibrosis

  1. Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-1-induced pulmonary fibrosis. Am J Respir Crit Care Med. 187(2):180-8, 2013 Jan 15.
  2. Interstitial lung disease in the connective tissue diseases. Clin Chest Med. 33(1):123-49, 2012 Mar.
  3. Possible mechanical roles of glycosaminoglycans in thoracic aortic dissection and associations with dysregulated transforming growth factor- J Vasc Res. 50(1):1-10, 2013.
  4. Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor--induced pulmonary fibrosis. J Biol Chem. 287(50):41991-2000, 2012 Dec 7.
  5. Keratoacanthoma: clinical and histopathologic features of regression. J Am Acad Dermatol. 67(5):1008-12, 2012 Nov.
  6. Lubiprostone targets prostanoid signaling and promotes ion transporter trafficking, mucus exocytosis, and contractility. Dig Dis Sci. 57(11):2826-45, 2012 Nov.
  7. Modulation of transforming growth factor- signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers. Circulation. 126(11 Suppl 1):S189-97, 2012 Sep 11.
  8. Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine. Traffic. 13(8):1072-82, 2012 Aug.
  9. Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-1 signaling. J Immunol. 189(5):2635-44, 2012 Sep 1.
  10. Inorganic phosphate stimulates fibronectin expression in renal fibroblasts. Cell Physiol Biochem. 30(1):151-9, 2012.
  11. Anti-fibrosis therapy and diabetic nephropathy Curr Diab Rep. 12(4):414-22, 2012 Aug.
  12. Unusual pulmonary findings in mucolipidosis II. Pediatr Pulmonol. 47(7):719-21, 2012 Jul.
  13. IL-18 induces emphysema and airway and vascular remodeling via IFN-, IL-17A, and IL-13. Am J Respir Crit Care Med. 185(11):1205-17, 2012 Jun 1.
  14. Review Series--Inflammation & Fibrosis. Fibrocytes and fibrosis. QJM. 105(6):505-8, 2012 Jun.
  15. Intestinal and plasma VEGF levels in cirrhosis: the role of portal pressure. J Cell Mol Med. 16(5):1125-33, 2012 May.
  16. Quantitative histological-hemodynamic correlations in cirrhosis. Hepatology. 55(4):1146-53, 2012 Apr.
  17. Gender and the extent of coronary atherosclerosis, plaque composition, and clinical outcomes in acute coronary syndromes. JACC Cardiovasc Imaging. 5(3 Suppl):S62-72, 2012 Mar.
  18. The role of Toll-like receptors in age-associated lung diseases. J Gerontol A Biol Sci Med Sci. 67(3):247-53, 2012 Mar.
  19. Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. Vascul Pharmacol. 56(1-2):47-55, 2012 Jan-Feb.
  20. Management of chronic hepatitis C infection in children. Curr Opin Pediatr. 24(1):113-20, 2012 Feb.
  21. Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101. Am J Physiol Cell Physiol. 302(1):C67-76, 2012 Jan 1.
  22. Combined pulmonary fibrosis and emphysema syndrome: a radiologic perspective. Monaldi Arch Chest Dis. 75(4):220-34, 2011 Dec.
  23. Tracheal stenosis and adenocarcinoma in an olive baboon (Papio cynocephalus anubis). Comp Med. 61(6):546-51, 2011 Dec.
  24. Nephrogenic systemic fibrosis: clinicopathological definition and workup recommendations. J Am Acad Dermatol. 65(6):1095-1106.e7, 2011 Dec.
  25. Studies of vascular endothelial growth factor in asthma and chronic obstructive pulmonary disease. [Review] Proc.Am.Thoracic Soc.. 8(6):512-5, 2011 Nov.
  26. Circulating fibrocytes--biology and mechanisms in wound healing and scar formation. Int Rev Cell Mol Biol. 291:1-19, 2011.
  27. Calcium-modulated chloride pathways contribute to chloride flux in murine cystic fibrosis-affected macrophages. Pediatr Res. 70(5):447-52, 2011 Nov.
  28. Primary diffuse large B-cell lymphoma of the testis. Arch Pathol Lab Med. 135(10):1363-7, 2011 Oct.
  29. Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-kB-mediated inflammatory response in mice. Gastroenterology. 141(4):1498-508, 1508.e1-5, 2011 Oct.
  30. The management of gastrointestinal disease in Hermansky-Pudlak syndrome. J Clin Gastroenterol. 45(8):700-2, 2011 Sep.
  31. Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. J Immunol. 186(12):6990-8, 2011 Jun 15.
  32. Incidence of encapsulating peritoneal sclerosis: a single-center experience with long-term peritoneal dialysis in the United States. Perit Dial Int. 31(3):279-86, 2011 May-Jun.
  33. Current usage and future directions for the bovine pericardial patch. Ann Vasc Surg. 25(4):561-8, 2011 May.
  34. Scraping fibrosis: expressway to the core of fibrosis. Nat Med. 17(5):552-3, 2011 May.
  35. Reticulon 4B (Nogo-B) is a novel regulator of hepatic fibrosis. Hepatology. 53(4):1306-15, 2011 Apr.
  36. A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells. J Cell Biol. 193(1):219-33, 2011 Apr 4.
  37. Imaging patients with kidney disease in the era of NSF: can it be done safely?. Clin Nephrol. 75(4):279-85, 2011 Apr.
  38. Imaging patients with kidney disease: how do we approach contrast-related toxicity?. Am J Med Sci. 341(3):215-21, 2011 Mar.
  39. Small intestinal neuroendocrine cell pathobiology: 'carcinoid' tumors. Curr Opin Oncol. 23(1):45-52, 2011 Jan.
  40. Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. [Review] Annu Rev Physiol. 73:479-501, 2011.
  41. Pregnancy in cystic fibrosis. Clin Chest Med. 32(1):111-20, ix, 2011 Mar.
  42. Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells. Hepatology. 53(2):548-57, 2011 Feb.
  43. "Clark/dysplastic" nevi with florid fibroplasia associated with pseudomelanomatous features. J Am Acad Dermatol. 64(2):346-51, 2011 Feb.
  44. Physiological relevance of cell-specific distribution patterns of CFTR, NKCC1, NBCe1, and NHE3 along the crypt-villus axis in the intestine. Am J Physiol Gastrointest Liver Physiol. 300(1):G82-98, 2011 Jan.
  45. Toxin mediated diarrhea in the 21 century: the pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection. Toxins (Basel). 2(8):2132-57, 2010 Aug.
  46. Identification and regulation of reticulon 4B (Nogo-B) in renal tubular epithelial cells. Am J Pathol. 177(6):2765-73, 2010 Dec.
  47. Clinical pharmacology of portal hypertension. Gastroenterol Clin North Am. 39(3):681-95, 2010 Sep.
  48. Recent advances in pulmonary fibrosis: implications for scleroderma. Curr Opin Rheumatol. 22(6):683-9, 2010 Nov.
  49. Ultrasound-based hepatic elastography: origins, limitations, and applications. J Clin Gastroenterol. 44(9):637-45, 2010 Oct.
  50. Cell death and fibrogenesis. Semin Liver Dis. 30(3):226-31, 2010 Aug.
  51. Drug-induced acute interstitial nephritis. Nat Rev Nephrol. 6(8):461-70, 2010 Aug.
  52. Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD. Nephrol Dial Transplant. 25(7):2187-94, 2010 Jul.
  53. Fibrocytes in health and disease. Exp Hematol. 38(7):548-56, 2010 Jul.
  54. Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Lab Invest. 90(6):812-23, 2010 Jun.
  55. Swarming motility, secretion of type 3 effectors and biofilm formation phenotypes exhibited within a large cohort of Pseudomonas aeruginosa clinical isolates. J Med Microbiol. 59(Pt 5):511-20, 2010 May.
  56. Portal fibroblasts: Underappreciated mediators of biliary fibrosis. Hepatology. 51(4):1438-44, 2010 Apr.
  57. Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct. Proc Natl Acad Sci U S A. 107(13):6082-7, 2010 Mar 30.
  58. Altered renal proximal tubular endocytosis and histology in mice lacking myosin-VI. Cytoskeleton. 67(3):178-92, 2010 Mar.
  59. Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. Mol Pharm. 7(1):86-93, 2010 Feb 1.
  60. Patients' preferences for treatment of hepatitis C. Med Decis Making. 30(1):45-57, 2010 Jan-Feb.
  61. Protein-protein interactions among ion channels regulate ion transport in the kidney. Bull Mem Acad R Med Belg. 164(3-4):133-41; discussion 141-2, 2009.
  62. Fibrosis of the hand secondary to jet propellant exposure: a new clinical syndrome. Plast Reconstr Surg. 124(5):266e-7e, 2009 Nov.
  63. Gadolinium-based contrast agents and nephrogenic systemic fibrosis: why did it happen and what have we learned?. J Magn Reson Imaging. 30(6):1236-9, 2009 Dec.
  64. Subretinal fibrosis and uveitis syndrome in a patient with ectodermal dysplasia. Ocul Immunol Inflamm. 17(5):348-50, 2009 Sep-Oct.
  65. Advanced kidney disease, gadolinium and nephrogenic systemic fibrosis: the perfect storm. [Review] [41 refs] Curr Opin Nephrol Hypertens. 18(6):519-25, 2009 Nov.
  66. Remedial operation for primary hyperparathyroidism. World J Surg. 33(11):2324-34, 2009 Nov.
  67. Update on rheumatology: part 2. Home Healthc Nurse. 27(9):535-9; quiz 540-1, 2009 Oct.
  68. Deletion of the Met receptor in the collecting duct decreases renal repair following ureteral obstruction. Kidney Int. 76(8):868-76, 2009 Oct.
  69. Diabetes mellitus and bone disease in cystic fibrosis. SEMIN. RESPIR. CRIT. CARE MED.. 30(5):514-30, 2009 Oct.
  70. Cystic fibrosis. SEMIN. RESPIR. CRIT. CARE MED.. 30(5):503, 2009 Oct.
  71. Evaluation of hepatic fibrosis with portal pressure gradient in rats. Magn Reson Med. 61(5):1185-92, 2009 May.
  72. Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med. 206(5):1149-66, 2009 May 11.
  73. Nephrogenic systemic fibrosis. Magn Reson Imaging Clin N Am. 17(1):159-67, 2009 Feb.
  74. Intracellular calcium signals regulate growth of hepatic stellate cells via specific effects on cell cycle progression. Cell Calcium. 45(3):284-92, 2009 Mar.
  75. A comparison of hepatopathologists' and community pathologists' review of liver biopsy specimens from patients with hepatitis C. Clin Gastroenterol Hepatol. 7(3):335-8, 2009 Mar.
  76. Current status of gadolinium toxicity in patients with kidney disease. Clin J Am Soc Nephrol. 4(2):461-9, 2009 Feb.
  77. Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/- mice. Am J Respir Cell Mol Biol. 40(3):295-304, 2009 Mar.
  78. Met and the epidermal growth factor receptor act cooperatively to regulate final nephron number and maintain collecting duct morphology. Development. 136(2):337-45, 2009 Jan.
  79. Toxin mediated diarrhea in the 21 century: the pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection. Toxins (Basel). 2(8):2132-57, 2010 Aug.
  80. Cell death and fibrogenesis. Semin Liver Dis. 30(3):226-31, 2010 Aug.
  81. Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct. Proc Natl Acad Sci U S A. 107(13):6082-7, 2010 Mar 30.
  82. Modulation of transforming growth factor- signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers. Circulation. 126(11 Suppl 1):S189-97, 2012 Sep 11.
  83. Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine. Traffic. 13(8):1072-82, 2012 Aug.
  84. Intestinal and plasma VEGF levels in cirrhosis: the role of portal pressure. J Cell Mol Med. 16(5):1125-33, 2012 May.
  85. Current usage and future directions for the bovine pericardial patch. Ann Vasc Surg. 25(4):561-8, 2011 May.
  86. Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells. Hepatology. 53(2):548-57, 2011 Feb.
  87. Physiological relevance of cell-specific distribution patterns of CFTR, NKCC1, NBCe1, and NHE3 along the crypt-villus axis in the intestine. Am J Physiol Gastrointest Liver Physiol. 300(1):G82-98, 2011 Jan.
  88. Identification and regulation of reticulon 4B (Nogo-B) in renal tubular epithelial cells. Am J Pathol. 177(6):2765-73, 2010 Dec.
  89. Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. J Immunol. 186(12):6990-8, 2011 Jun 15.
  90. Scraping fibrosis: expressway to the core of fibrosis. Nat Med. 17(5):552-3, 2011 May.
  91. Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. Vascul Pharmacol. 56(1-2):47-55, 2012 Jan-Feb.
  92. Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-1-induced pulmonary fibrosis. Am J Respir Crit Care Med. 187(2):180-8, 2013 Jan 15.
  93. The role of Toll-like receptors in age-associated lung diseases. J Gerontol A Biol Sci Med Sci. 67(3):247-53, 2012 Mar.
  94. Tracheal stenosis and adenocarcinoma in an olive baboon (Papio cynocephalus anubis). Comp Med. 61(6):546-51, 2011 Dec.
  95. Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-kB-mediated inflammatory response in mice. Gastroenterology. 141(4):1498-508, 1508.e1-5, 2011 Oct.
  96. Reticulon 4B (Nogo-B) is a novel regulator of hepatic fibrosis. Hepatology. 53(4):1306-15, 2011 Apr.
  97. Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology. 46(5):1509-18, 2007 Nov.
  98. Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-1 signaling. J Immunol. 189(5):2635-44, 2012 Sep 1.
  99. Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. Annu Rev Physiol. 73:479-501, 2011.
  100. Fibrocytes in health and disease. Exp Hematol. 38(7):548-56, 2010 Jul.