Clemens Bergwitz, MD

Clemens W.H. Bergwitz, MD, is an endocrinologist and Associate Professor of Medicine. In 2006, he identified the genetic defect underlying the childhood disorder Hereditary Hypophosphatemic Rickets with Hypercalciuria (HHRH), and since then, he has developed a research focus on inborn errors of bone and mineral metabolism. He leads several clinical trials and his lab uses murine models of hypophosphatemia to understand better the responses of the musculoskeletal and renal systems to oral phosphate therapy. Using genome-wide RNAi screens, a more recent research interest is in trying to understand how human and other metazoan cells sense inorganic phosphate and to identify mammalian systems suitable to study identified hits. He also attends the Endocrine Consult Service at Yale New Haven Hospital and, as a member of the Yale Medical Group, sees outpatients with hypophosphatemic disorders, osteoporosis, primary hyperparathyroidism, hyperthyroidism, thyroid nodules, hypogonadism, adrenal, and general endocrine disorders.