Professor of Medicine (Hematology); Director, Hematology/Oncology Fellowship Program
Leadership and Core Faculty
Directors
- Dr. Alfred Ian Lee is Professor of Medicine (Hematology) and Program Director for the hematology/oncology fellowship program. He received his MD/PhD from the Yale School of Medicine in 2004. Dr. Lee completed residency in internal medicine at Brigham & Women’s Hospital, where he served as Chief Medical Resident, followed by a fellowship in hematology/oncology at Dana-Farber Cancer Institute. His primary academic interests are classical hematology, thrombosis, and medical education. He has received such honors as the Charles W. Bohmfalk Prize for teaching in the basic sciences, the Leah M. Lowenstein Award for excellence in the promotion of humane and egalitarian medical education, the Yale Cancer Center Award for Mentorship Excellence, and the David J. Lefell Prize for Clinical Excellence.
Associate Professor of Internal Medicine (Hematology); Duffy Firm Chief for Education, Department of Internal Medicine; Associate Director of the Hematology/Oncology Fellowship Program
Research Interests- Leukemia
- Myelodysplastic Syndromes
- Myeloproliferative Disorders
Dr. Nikolai Podoltsev is an Associate Professor of Medicine (Hematology). His practice is focused on management of patients with acute leukemias, including acute myeloid leukemias (AML) and acute lymphoblastic leukemia (ALL) as well as myeloid neoplasms like myelodisplastic syndromes (MDS) and myeloproliferative neoplasms (MPNs), such as polycythemia vera (PV), essential thrombocythemia (ET), myelofibrosis (MF), and chronic myeloid leukemia (CML) among others. He also provides care for patients with aplastic anemia and bone marrow failure syndromes and follows patients with clonal hematopoiesis of indeterminate potential (CHIP), and systemic mastocytosis and hypereosinophilic syndrome. He is the director of the Hematology/Leukemia Tumor Board. As the Associate Director of the Yale Hematology/Oncology Fellowship Program and Yale-New Haven Hospital Duffy Firm Chief for Education, Dr. Podoltsev is involved in organizing and providing hematology education for hematology/medical oncology fellows, internal medicine residents, and medical students. The Yale Cancer Outcomes Public Policy and Effectiveness Research (COPPER) Center membership helps Dr. Podoltsev to study epidemiology, and the patterns of care and outcomes of patients with hematological malignancies. Dr. Podoltsev is engaged in the clinical research programs of the Leukemia Disease Aligned Research Team (DART) as a Principal Investigator for multiple clinical trials enrolling patients with acute leukemias and myeloid malignancies.Associate Professor of Internal Medicine (Medical Oncology)
Research Interests- Neoplastic Processes
Associate Professor of Internal Medicine (Medical Oncology); Associate Director, Medical Oncology-Hematology Program; Research Director, Center for Thoracic Cancers; Chief, Thoracic Oncology
Research Interests- Carcinoma, Non-Small-Cell Lung
- Immunotherapy
- Lung
- Medical Oncology
- Thoracic Neoplasms
Dr. Sarah Goldberg is an Associate Professor of Medicine in the section of Medical Oncology at the Yale School of Medicine. As a thoracic oncologist she cares for patients with cancers of the chest including lung cancer, mesothelioma and thymoma. She is the Division Chief of Thoracic Oncology, the Research Director for the Center for Thoracic Cancers, and the Associate Program Director for the Medical Oncology-Hematology Fellowship Program at Yale. She received her medical degree from Mount Sinai School of Medicine and completed a Masters in Public Health degree from the Harvard School of Public Health. She conducts clinical and translational research on lung cancer with a focus on investigating biomarkers and novel treatment strategies in non-small cell lung cancer. Her specific research interests include EGFR mutation positive lung cancer, immunotherapeutics for lung cancer, and brain metastases. Learn more about Dr. Sarah Goldberg>>Arthur H and Isabel Bunker Associate Professor of Medicine (Hematology) and Associate Professor of Pathology; Chief, Section of Hematology; Director, DeLuca Center for Innovation in Hematology Research, Yale Cancer Center; Assistant Medical Director CRSL, Yale Cancer Center
Research Interests- Hematopoiesis
- Hematopoietic Stem Cells
- Leukemia
- Myelodysplastic Syndromes
- RNA Splicing
- Alternative Splicing
- Xenograft Model Antitumor Assays
Dr. Halene is a physician-scientist who received her MD degree at Eberhardt-Karls-University in Tübingen, Germany. She subsequently completed a postdoctoral fellowship in the laboratory of Donald B. Kohn at CHLA in Los Angeles and her residency in internal medicine at Yale New Haven Hospital. She completed her fellowship in hematology/oncology at Yale and joined the ladder faculty at YSM as an assistant professor in 2010. At that time she was also named director of the Hematology Tissue Bank for Yale Cancer Center. She was promoted to associate professor in 2016 and subsequently served as interim chief of the Section of Hematology prior to her appointment as chief of that section in 2020. Her laboratory studies hematopoiesis and myelopoiesis and in particular how mutations in splicing factors and perturbations in RNA modifications contribute to hematologic malignancies such as myelodysplasia and leukemia. Dr. Halene, in collaboration with the Flavell laboratory in the YSM Department of Immunobiology, has developed the first efficient xenotransplantation model in humanized mice to study myelodysplasia and enable testing of novel drug treatments. Dr. Halene’s research has garnered significant attention from the international community, as evidenced by numerous invited speaking engagements, an invitation to serve as a section editor on myeloid malignancies for a major journal, and publications in top tier journals in her field. In 2015 she was presented with the Sir William Osler Young Investigator Award and in 2019 was elected a member of the Interurban Clinical Club. Dr. Halene is director of the DeLuca Center for Innovation in Hematology Research. Through generous funding from The Frederick A. DeLuca Foundation, the center has established a comprehensive biospecimen bank, awarded pilot and career development grant funding to advance cutting-edge discoveries in hematologic malignancies and classical hematologic disorders. Meet Dr. Stephanie Halene>>Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology; Director, Center for Thoracic Cancers; Assistant Dean for Translational Research, Office of the Dean, School of Medicine; Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital; Deputy Director, Yale Cancer Center; Co-Principal Investigator and Community Outreach Co-Leader, Cancer Disparities Firewall Project
Research Interests- Lung Neoplasms
- Medical Oncology
- Thoracic Neoplasms
- Clinical Trials, Phase I as Topic
- Biomarkers, Pharmacological
- Precision Medicine
Dr. Herbst is nationally recognized for his leadership and expertise in lung cancer treatment and research. He is best known for his work in developmental therapeutics and the personalized therapy of non-small cell lung cancer, in particular the process of linking genetic abnormalities of cancer cells to novel therapies. Learn more about Dr. Herbst >>Prior to his appointment at Yale, Dr. Herbst was the Barnhart Distinguished Professor and Chief of the Section of Thoracic Medical Oncology in the Department of Thoracic/Head and Neck Medical Oncology, at The University of Texas M.D. Anderson Cancer Center (UT-MDACC) in Houston, Texas. He also served as Professor in the Department of Cancer Biology and Co-Director of the Phase I Clinical Trials Program.Dr. Herbst’s primary mission is the enhanced integration of clinical, laboratory, and research programs. He has worked over several decades as a pioneer of personalized medicine and immunotherapy to identify biomarkers and bring novel targeted treatments and immunotherapies to patients, serving as principal investigator for numerous clinical trials testing these agents in advanced stage lung cancers. This work led to the approval of several therapies (such as gefitinib, cetuximab, bevacizumab, axitinib), which have revolutionized the field and greatly enhanced patient survival. He and his Yale colleagues were among the first to describe the PD-1/PD-L1 adaptive immune response in early phase trials and to offer trials of PD-L1 inhibitors atezolizumab and pembrolizumab to lung cancer patients. His leadership in targeted therapeutics resulted in a 2020 ASCO plenary talk and publication of results of the third-generation EGFR-inhibitor osimertinib for the treatment of resected EGFR-mutant NSCLC in the New England Journal of Medicine.In 2015 and again in 2020, his team at Yale was awarded a Lung Cancer SPORE (P50 grant) by the National Cancer Institute (NCI), which has identified new immunotherapies and mechanisms of sensitivity and resistance to EGFR targeted therapies. His work has also been funded by ASCO, AACR, the United States Department of Defense, and by a AACR/ Stand Up to Cancer Dream Team grant.His work on "umbrella” trials has galvanized the field of targeted therapy and cancer drug approvals at the FDA. Nationally, he works closely with public-private partnerships to develop large master protocol clinical studies. He was co-leader for the BATTLE-1 clinical trial program, co-leads the subsequent BATTLE-2 clinical trial program. and is principal investigator (PI) of the Lung Master Protocol (Lung-MAP). He testified on this before the House of Representatives 21st Century Cures committee and served as a prominent figure in this area, for nine years as a member of the National Academy of Medicine’s Cancer Policy Forum, for which he organized several meetings focused on policy issues in personalized medicine and tobacco control. He is currently the Vice Chair for Developmental Therapeutics for the Southwestern Oncology Group (SWOG) Lung Committee and PI of the SWOG 0819 trial.After earning a B.S. and M.S. degree from Yale University, Dr. Herbst earned his M.D. at Cornell University Medical College and his Ph.D. in molecular cell biology at The Rockefeller University in New York City, New York. His postgraduate training included an internship and residency in medicine at Brigham and Women’s Hospital in Boston, Massachusetts. His clinical fellowships in medicine and hematology were completed at the Dana-Farber Cancer Institute and Brigham and Women’s Hospital, respectively. Subsequently, Dr. Herbst completed a M.S. degree in clinical translational research at Harvard University in Cambridge, Massachusetts.Dr. Herbst is a highly respected clinician scientist who has been a champion of translational medicine for decades, recently authoring a high-profile review of the 20-year progress in lung cancer. He has authored or co-authored more than 350 publications, including peer-reviewed journal articles, abstracts, and book chapters. His work has appeared in many prominent journals, such as the Journal of Clinical Oncology, Clinical Cancer Research, Lancet, and the New England Journal of Medicine. Work published in Nature was awarded the 2015 Herbert Pardes Clinical Research Excellence Award by the Clinical Research Forum. His abstracts have been presented at the annual meetings of the American Society of Clinical Oncology (ASCO), the American Association for Cancer Research (AACR), the World Conference on Lung Cancer, the Society of Nuclear Medicine Conference, and the European Organization for Research and Treatment of Cancer.He is a Fellow of the American Society of Clinical Oncology and a member of the American Association of Cancer Research (AACR), where serves as Chair of the AACR Scientific Policy and Government Affairs Committee. He has been a major proponent of efforts to promote tobacco control and regulation (including e-cigarettes), authoring multiple policy statements and leading frequent Capitol Hill briefings. In 2019, he was elected to the International Association for the Study of Lung Cancer (IASLC) board of directors. He is a fellow of the American College of Physicians and an elected member of the Association of American Physicians. He is vice chair of the Southwestern Oncology Group’s (SWOG) Lung Committee.For his lifetime achievement in scientific contributions to thoracic cancer research, Dr. Herbst was awarded the 2016 Paul A. Bunn, Jr. Scientific Award by the IASLC at their 17th World Conference on Lung Cancer in Vienna, Austria. A team of Yale Cancer Center investigators led by Roy S. Herbst, MD, PhD, was awarded the 2018 Team Science Award from the Association for Clinical and Translational Science (ACTS) for its pioneering work in advancing our understanding of Immunotherapy. In 2020, Dr. Herbst was awarded the AACR Distinguished Public Service Award for Exceptional Leadership in Cancer Science Policy. Dr. Herbst is the recipient of the 2022 Giants of Cancer Care® award for Lung Cancer and was honored by Friends of Cancer Research in 2022 as one of their 25 scientific and advocacy leaders who, through their work and partnership, have been instrumental over the course of the last 25 years in making significant advancements for patients.Professor; Director, VA Comprehensive Cancer Center
Research Interests- Health Services Research
- Hematology
- Medical Oncology
- Veterans
Alfred Gilman Professor of Pharmacology and Professor of Medicine (Medical Oncology); Director, Yale Cancer Center; Physician-in-Chief, Smilow Cancer Network; Alfred Gilman Professor, Medicine and Pharmacology
Research Interests- Breast
Dr. Eric Winer is the Director of Yale Cancer Center and Physician-in-Chief of Smilow Cancer Network as of February 1, 2022. An internationally renowned expert in breast cancer, Dr. Winer has led and collaborated on innumerable clinical trials that have changed the face of the disease. His work is both broad and deep, and it has touched almost all aspects of breast cancer. Dr. Winer has long been an advocate of building teams consisting of scientists and clinicians to accelerate progress in cancer research and care. Dr. Winer is President of the American Society of Clinical Oncology (ASCO) and a member of the Scientific Advisory Board of the Breast Cancer Research Foundation. For over a decade, he served as chief scientific advisor and chair of the Scientific Advisory Board for Susan G. Komen for the Cure. For the past six years he has co-led the National Cancer Institute Breast Cancer Steering Committee. Dr. Winer has published over 350 original manuscripts and mentored over 30 fellows and junior faculty. In recognition of his mentoring impact, he was the recipient of the William Silen Lifetime Achievement in Mentoring Award from Harvard Medical School in 2020. He has also received numerous awards for his breast cancer research, most notably the William L. McGuire Memorial Lecture Award in 2016 at the San Antonio Breast Cancer Symposium.Dr. Winer is an alumnus of both Yale College and Yale School of Medicine. After receiving his medical degree in 1983, he completed training in internal medicine and served as chief resident at Yale New Haven Hospital. He completed a fellowship in hematology/oncology at Duke University School of Medicine and served on the Duke faculty from 1989 to 1997. He then joined Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and Harvard Medical School where he has spent the last 24 years. Most recently, he held the Thompson Chair in Breast Cancer Research and served as chief clinical development officer, and senior vice president for medical affairs at Dana-Farber Cancer Institute, as well as Professor of Medicine at Harvard Medical School.
Core Faculty
Assistant Professor of Medicine (Hematology)
Noffar Bar, MD, is an Assistant Professor of Medicine (Hematology) at Yale School of Medicine and completed her internship and residency at the Mount Sinai Hospital and her fellowship at Yale. She received her medical degree from the Sackler School of Medicine New York State/American Program of Tel Aviv University. Dr. Bar is a member of the American Society of Clinical Oncology, the American Society of Hematology, and the International Myeloma Society. Dr. Bar’s research is focused on multiple myeloma and other plasma cell disorders. She specializes in all treatment modalities for myeloma including CAR T-cell therapy and stem cell transplant. She received grant support through the Conquer Cancer Foundation’s Young Investigator Award for her work looking at the prevention of multiple myeloma. Dr. Bar is dedicated to improving treatments for myeloma patients through innovative clinical trials. Additionally, Dr. Bar is a medical educator and a member of the Classical Hematology Disease team at Yale. She is interested in promoting high value care for hematology patients.Associate Professor of Medicine (Medical Oncology); Disease Aligned Research Team Leader, Head and Neck Cancers Program
Research Interests- Head and Neck Neoplasms
- Medical Oncology
Associate Professor of Medicine (Medical Oncology); Disease Aligned Research Team (DART) Leader Sarcoma, Medical Oncology; Director Medical Oncology Inpatient Consult Service, Medical Oncology
Research Interests- Chondrosarcoma
- Leiomyosarcoma
- Liposarcoma
- Osteosarcoma
- Soft Tissue Neoplasms
- Sarcoma, Synovial
- Thyroid Neoplasms
- Neoplasms, Connective and Soft Tissue
- Liposarcoma, Myxoid
Dr. Hari Deshpande, Associate Professor of Medicine in the Section of Medical Oncology, cares for patients with sarcomas along with the sarcoma multidisciplinary team.Previously in practice at both the New London Cancer Center and Las Vegas Cancer Center, Dr. Deshpande also has clinical interests in sarcomas, cancers of unknown primary, and thyroid cancers. He is a member of the Head and Neck Cancer and GU cancer teams. He is the Director of the Medical Oncology Inpatient Consult service.Learn more about Dr. Deshpande>>Professor Adjunct
Research Interests- Signal Transduction
- Clinical Trial
- Clinical Trial, Phase I
- Precision Medicine
I was the principal clinical investigator of the Harvard UO1 Phase I program in 1995, uniting the clinical efforts at the DFCI, BWH, MGH and BIDMC. In 1998, I became the Clinical Director of the Experimental Therapeutics Program for the Dana-Farber/Harvard Cancer Center. As Clinical Director, I assumed overall responsibility for the trials performed at the DF/HCC. In 2004 I assumed the responsibilities as the Clinical Director of the DFCI General Cancer Research Center at the Dana-Farber/ Brigham and Women’s Hospital. These clinical and basic research activities have involved collaboration with clinical and basic scientists at Harvard and elsewhere, the Cancer Therapy Evaluation Program of the National Cancer Institute, presentations at national and international meetings, and correspondence with a number of leaders in the field of cancer drug development. At AstraZeneca PLC, I was the Medical Science Director for AstraZeneca’s Boston site, responsible for the medical and clinical aspects of development of agents from chemical lead identification through clinical proof of concept in phase II. I was responsible for the design and interpretation of the entire clinical development plan for five agents. This position had global responsibilities with clinical trials in the US, Canada, European Union, Japan and Korea. I was a member of the Strategic Planning & Business Development as an ad hoc member and was the global Disease Area Clinical Expert for Hematology.Professor of Medicine (Hematology) and of Dermatology; Director, Multidisciplinary T cell Lymphoma Program, Hematology; Scientific Leader, Lymphoma DART, Yale Cancer Center; Host, Yale Cancer Center Answers, Yale Cancer Center
Research Interests- Biological Factors
- Graft vs Host Disease
- Hodgkin Disease
- Immune System Diseases
- Leukemia, Hairy Cell
- Leukemia, Lymphoid
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Sezary Syndrome
- Skin Neoplasms
- Leukemia, B-Cell
- Leukemia, T-Cell
- Leukemia, Prolymphocytic, T-Cell
- Leukemia, Prolymphocytic, B-Cell
- Composite Lymphoma
- Chemicals and Drugs
Dr. Francine Foss, Professor of Medicine in the Section of Medical Oncology at the Yale Cancer Center, is an internationally recognized clinician and clinical researcher with expertise in adult lymphomas and in stem cell transplantation. She has developed and tested therapies that have been used to treat thousands of cancer patients, and her research has substantially impacted the field of stem cell research, benefiting patients at Yale and around the world. Dr. Foss has brought a nationally established clinical trials program to the Yale Cancer Center. In her previous position at Tufts New England Medical Center in Boston, she designed, initiated, and directed multi-center national clinical trials which led to FDA approval of several novel therapies for lymphomas. One of these, Interleukin-2- Diphtheria toxin fusion protein, was the first FDA-approved fusion protein biologic drug and the first drug to be FDA approved for the treatment of T-cell lymphoma. In her laboratory work, she investigated and elucidated the mechanism by which extracorporeal photopheresis modulated antigen presenting cells, leading to a reduction in graft-vs-host disease in patients undergoing allogeneic stem cell transplant. These findings led to the initiation of two National Cancer Institute-sponsored trials to confirm these results in patients with lymphoma and myelodysplastic syndrome. Dr. Foss is a member of the Stem Cell Therapy clinical program at the Smilow Cancer Center. Learn more about Dr. Foss>>Dr. Foss is a world expert in T cell Lymphomas. She has pioneered several novel therapies for T cell lymphomas and has been a leader in many national studies. She developed and initiated the first national registry for T cell lymphomas in the United States and is a founder and co-chairman of the T CELL Forum, the preeminent international T cell lymphoma research meeting. She is a co-founder of the United States Cutaneous Lymphoma Consortium and currently serves as its President. She has been a Director of the international T-cell Project to research treatment and biology of T-cell lymphomas and serves on the NCCN panel of experts for T-cell lymphomas. As a translational researcher in T cell Lymphomas, she currently is collaborating with a number of laboratories and scientists at Yale to identify molecular targets in T Cell Lymphoma and recently was awarded a grant through the PITCH program for the state of Connecticut to develop a promising small molecule therapeutic for a rare form of lymphoma. Dr. Foss currently leads the multi-disciplinary T-cell Lymphoma clinical team at the Smilow Cancer Center and co-directs the Cutaneous Lymphoma Program at Yale with Dr. Michael Girardi. Her clinical practice at the Smilow Cancer Center attracts patients from around the world. In addition, Dr Foss has been one of the early developers and hosts of the Yale Cancer Answers, a weekly program on Connecticut National Public Radio.Assistant Professor of Medicine (Hematology); Assistant Professor of Medicine (Hematology), Internal Medicine
Research Interests- Anemia, Aplastic
- Blood Transfusion
- Bone Marrow Diseases
- Immunotherapy
- Leukemia
- Lymphoma
- Multiple Myeloma
- Myelodysplastic Syndromes
- Hematopoietic Stem Cell Transplantation
- Primary Myelofibrosis
Curing hematologic cancers with precision medicine and minimal toxicity has been a multigeneration challenge and a highly prioritized work for our group at Yale. Through continual engagement with patients and their families, educational meetings and well informed decision making sessions, we help our patients navigate the field of transplantation and cellular therapy. Our multidisciplinary team while trying to harness the curative promise of cellular immunotherapy also has special focus to enhance its safety and provide long term supervision for cancer survivors. We strongly encourage our patients to learn the strengths and limitations of the existing standard of care, the knowledge of which could be applied to personalize treatment plans and foster research environment to advance the broader field.Assistant Professor; Assistant Professor (Medical Oncology)
Research Interests- Clinical Trial
- Clinical Trial, Phase I
Navid Hafez, MD, MPH completed his residency and fellowship at Yale and his received his medical degree from the University of Wisconsin School of Medicine and Public Health.Associate Professor of Internal Medicine (Hematology); Medical Director, Hematology Outpatient Program
Research Interests- Hematologic Diseases
- Insurance
- Lymphoma
Scott Huntington, MD, MPH is a clinician and researcher at the Yale School of Medicine specializing in the care of patients with lymphoma and chronic lymphocytic leukemia. He is an Associate Professor of Medicine (Hematology) and the Medical Director of Yale Cancer Center's Hematology Outpatient Program. Prior to joining Yale, he completed his hematology-oncology training and received a Master of Science in Health Policy Research at the University of Pennsylvania. Dr. Huntington serves as an investigator on clinical trials evaluating novel cancer therapeutics and is an active member of Yale’s Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, where he leads research focused on improving the delivery of complex cancer treatment during routine care.Associate Professor of Medicine (Hematology); Co-Director Adult CAR T-Cell Therapy Program, Hematology; Co-Leader, Cellular Therapy Disease Aligned Research Team (DART), Yale Cancer Center; Co-Chair, Cellular Therapy (CT)-SAFE Committee, Yale Cancer Center
Research Interests- Clinical Trials as Topic
- Graft vs Host Disease
- Lymphoma
- Bone Marrow Transplantation
- Clinical Trials, Phase I as Topic
- Transplantation Conditioning
Associate Professor of Internal Medicine (Medical Oncology); Director, Prostate Cancer Research; Lecture Coordinator in Hematology/Oncology, Yale Affiliated Hospital Program
Dr. Joseph Kim is a board-certified medical oncologist and a Director of the Prostate Cancer Research Program for Prostate and Urological Cancers DART of Yale Cancer Center. He is a recipient of the Cancer Clinical Investigator Team Leadership Award from the National Cancer Institute (NCI) and a recipient of other awards from Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO). Dr. Kim has led several peer-reviewed, NCI-sponsored, investigator-initiated clinical trials in prostate cancer, bladder cancer, and other solid tumors as a study chair. Dr. Joseph Kim serves as an author/editor of the genitourinary (GU) cancers chapter of ASCO-SEP, an educational textbook for medical oncologists, and a co-editor of the GU cancers section of a peer-reviewed journal, Current Oncology Report, and ad hoc reviewer of multiple oncology journals. He has been invited as a speaker for numerous international and national academic conferences including GU Cancers Symposium, ASCO Annual Meeting, CTEP/ NCI meeting, ASCO Direct highlights, International Genitourinary Cancer Conference, and many others. His passion lies in delivering compassionate, patient-centered, and evidence-based care for patients with genitourinary cancer including prostate cancer, bladder, and other urinary tract cancer, testicular cancer, and penile cancer. He is also passionate about developing and executing hypothesis-driven clinical trials of novel therapies in GU cancers and other solid tumors.Harvey and Kate Cushing Professor of Medicine (Oncology) and of Dermatology; Director, Yale SPORE in Skin Cancer, Yale Cancer Center; Vice Chair for Translational Research, Internal Medicine; Chief, Division of Skin and Kidney Cancer; Associate Cancer Center Director, Education, Training and Faculty Development; Deputy Section Chief, Medical Oncology
Research Interests- Medical Oncology
- Melanoma
Dr. Kluger is a medical oncologist who sees patients with melanoma and renal cell carcinoma. Her research interests focus on developing new drug regimens and biomarkers predictive of response to therapies in melanoma and renal cell carcinoma. She participates in a number of clinical trials studying new agents for the treatment of these diseases, both targeting the immune system and the cancer cell. She runs an active research laboratory that studies tumor and immune cells from patients treated with novel therapies to determine mechanisms of resistance to therapy and mediators of toxicity from immune checkpoint inhibitors. The laboratory also conducts pre-clinical studies to improve treatment regimens for patients with melanoma, renal cell carcinoma or brain metastasis. Learn more about Dr. Kluger>>Assistant Professor of Medicine (Hematology)
Research Interests- Drug Resistance
- Apoptosis
- Lymphoma, Mantle-Cell
Shalin Kothari, MD is an Assistant Professor of Medicine (Hematology) at Yale University. Dr. Kothari completed his residency in Internal Medicine at SUNY Upstate Medical University and his Hematology and Medical Oncology fellowship through the University at Buffalo/Roswell Park Comprehensive Cancer Center where he was the Chief Fellow. He received his Medical Degree from Gujarat University in India. Dr. Kothari specializes in the treatment of lymphomas. His research is focused on using his clinical skills and basic science knowledge to answer scientific questions focused on mechanistic understanding of lymphoma therapeutics and its translation in the form of early-phase clinical trials for various aggressive forms of B-cell lymphomas including mantle cell lymphoma. He also conducts research in the Katz Laboratory here at Yale University with a specific focus on developing new therapies for mantle cell lymphoma.He is a Lymphoma Research Foundation (LRF) Scholar, and an inductee of the ASH Advocacy Leadership Institute and the Gold Humanism Honor Society. He has presented his research in multiple national and international meetings and has won abstract achievement and travel awards.Professor of Medicine (Medical Oncology)
Dr. Jill Lacy is Professor of Medicine in the Section of Medical Oncology at Yale School of Medicine with over 30 years of experience as a practicing Medical Oncologist. Dr. Lacy graduated from Yale School of Medicine in 1978, completed training in Internal Medicine and Medical Oncology at Yale, and is board-certified in Internal Medicine and Medical Oncology. Dr. Lacy's early career was focused on clinical and basic research related to Epstein Barr virus-mediated oncogenesis and HIV-associated malignancies during the height of the AIDS epidemic. In recent years, Dr. Lacy's clinical practice has been devoted to caring for patients with gastrointestinal malignancies. Her current research is focused on therapeutic clinical trials in GI malignancies, including gastroesophageal, pancreatic, and colorectal cancers. She is the principle investigator on a number of investigator-initiated, pharmaceutical, and cooperative group studies. She has served on national committees focused on optimizing the education of Medical Oncology trainees and recruiting minority students to careers in Oncology.Associate Professor of Internal Medicine (Hematology); Research Leader, Myeloma Program, Hematology
Research Interests- Amyloidosis
- Hematology
- Leukemia, Plasma Cell
- Waldenstrom Macroglobulinemia
- Multiple Myeloma
- Myeloma Proteins
- Paraproteinemias
- Neoplasms, Plasma Cell
- Smoldering Multiple Myeloma
Dr. Neparidze obtained her medical degree from Aieti Medical School in Tbilisi, Georgia in 2000. She subsequently completed Postdoctoral Research Fellowships at Emory, Northwestern and Yale Universities, followed by Internal Medicine Residency and Hematology/Medical Oncology Fellowship at Yale University. She has served as an assistant professor at Yale University School of Medicine, Medical Oncology/Hematology since 2012. She specializes in multiple myeloma, monoclonal gammopathies, AL amyloidosis, Waldenstrom's macroglobulinemia. Dr. Neparidze has developed multiple research projects in myeloma, including a number of investigator-initiated therapeutic clinical trials. She collaborates with other researchers nationally and internationally, serve as a PI and co-PI on multiple therapeutic clinical trials and leads several clinical outcomes studies in patients with myeloma. She serves as the leader of the Yale Myeloma Research team. Her ongoing research directions include use of advanced imaging and evaluating tumor heterogeneity to enhance precision medicine approaches for myeloma, novel combination immunotherapy strategies and MRD-driven therapies in myeloma, as well as studying biology and clinical outcomes of monoclonal gammopathies in association with metabolic, viral and other co-morbidities, investigating mechanisms of tumor progression and resistance in myeloma. Dr. Neparidze is actively involved in educational process, teaching Hematology/Oncology fellows, medical students, residents and colleagues at Yale and in community. Learn more about Dr. Neparidze>>Associate Professor of Medicine (Medical Oncology); Chief, Patient Experience Officer; Medical Director, Survivorship Clinic
Research Interests- Breast Diseases
- Communication
- Survivorship
I am board certified in both medical oncology and hospice and palliative medicine, which I feel helps me treat the "whole person" and not just a disease. As the Chief Patient Experience Officer at Smilow Cancer Hospital, I enjoy thinking about improving care, especially where the provider and patient experience overlaps. As a breast oncologist, I have a busy practice and enjoy taking care of women with newly diagnosed breast cancer. As the director of the Yale Survivorship Clinic, one of the nation’s only multi-disciplinary clinics specializing in cancer survivorship, I learn from patients about key issues after treatment and this informs my role as Chair of the NCCN Survivorship Guidelines. My research focuses on healthy lifestyles and quality of life after cancer. I am a facilitator for Relationship-Centered Communication Workshop that address how we develop therapeutic relationships with our patients and each other. Learn more about Dr. Tara Sanft>>Associate Professor of Medicine (Medical Oncology); Chief, Ambulatory Officer
I am an Associate Professor of Medicine in the section of Medical Oncology within the Department of Medicine, and in the clinic, I see patients with breast cancer. I am also involved in education of students, residents, and fellows here at Yale. Outside of the clinic, I am involved with the COPPER (Cancer Outcomes, Public Policy, and Effectiveness Research) Center within the School of Medicine, with a specific interest in chemotherapy regimens used in the treatment of breast cancer and how they are used in clinical practice.Learn more about Dr. Schellhorn>>Professor of Internal Medicine (Hematology); Acting Director, Stem Cell Transplantation; Chairman, Car-T Cell Joint Steering Committee; Director, Unrelated Donor Transplant Program, Stem Cell Transplantation; Co-Director, Immune Effector Cell Therapy; Co-Director, Adult CAR T-Cell Therapy Program
Research Interests- Hematologic Diseases
- Hematopoietic Stem Cells
- Hodgkin Disease
- Leukemia
- Lymphocytes
- Lymphoma
- Lymphoma, Non-Hodgkin
- Plasma Cells
- Bone Marrow Transplantation
- Clinical Trials, Phase III as Topic
Dr. Seropian is a Professor of Medicine in the department of Internal Medicine, Section of Hematology, Yale University School of Medicine. He received his medical degree from George Washington University School of Medicine and completed residency and fellowship training at Yale-New Haven Hospital/Yale University School of Medicine in 1996. Dr. Seropian serves as Interim Director of the Stem Cell Transplant Program, Co-Director, Immune Effector Cell Therapy, and Chairman, Car-T Cell Joint Steering Committee, Yale-New Haven Hospital. Dr. Seropian’s research interests include methods to improve the outcomes of transplantation through use of novel anti-cancer agents and new methods of treating graft versus host diseaseAssistant Professor of Medicine (Hematology)
Research Interests- Epidemiology
- Leukemia
- Myelodysplastic Syndromes
- Myeloproliferative Disorders
- Myelodysplastic-Myeloproliferative Diseases
Dr. Shallis received his MD from Rutgers-Robert Wood Johnson Medical School, completed his residency training at Brown University-Rhode Island Hospital and fellowship training at Yale-New Haven Hospital. He is focused on the care and research of patients with myeloid malignancies, particularly acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). He also participated in the K12 Calabresi Immuno-Oncology Training Program and currently participates as an investigator in several clinical trials aimed at improving the outcomes of patients with AML and MDS. Dr. Shallis also maintains research interest in epidemiological, outcomes and effectiveness research as it pertains to the hematologic malignancies with a goal of identifying barriers to effective care and ultimately strategies to improve the outcomes of patients with these malignant diseases. Dr. Shallis conducts research with the Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center at Yale University. Dr. Shallis has presented his research at multiple regional, national and international meetings and is a member of the National Comprehensive Cancer Network (NCCN) clinical guidelines for MDS and AML panels. He is an author on more than 75 peer-reviewed publications and book chapters, most of which as first author and has served as an ad hoc reviewer for many journals including Leukemia, Haematologica, Blood Advances, Leukemia Research, Leukemia & Lymphoma, Acta Haematologica, Hematology, Therapeutic Advances in Hematology, Expert Review of Hematology, BMC Hematology, eJHaem and Future Oncology among others.Associate Professor of Internal Medicine (Medical Oncology); Assistant Medical Director, Clinical Trials Office
Research Interests- Gastrointestinal Neoplasms
- Clinical Trial
I take care of patients with advanced liver cancer and offer chemotherapy. I help educate my patients and their families about their cancer and liver disease. Treatment plans often include a pill form of targeted therapy. There are also immune therapy clinical trials available for patients. I work closely with patients to manage their cancer and liver disease related symptoms.Learn more about Dr. Stacey Stein>>