Michael Simons, MD, FACC, FAHA

Professor of Medicine (Cardiology)

Departments & Organizations

Internal Medicine: Cardiovascular Medicine: Yale Cardiovascular Research Center | Simons Lab

Developmental Cell Biology and Genetics

Vascular Biology and Therapeutics Program

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Office of Cooperative Research


Dr. Simons is a graduate of Massachusetts Institute of Technology and Yale School of Medicine. He completed his clinical training in internal medicine at the New England Medical Center in Boston and cardiology training at the Beth Israel Hospital in Boston. He completed a postdoctoral fellowships in molecular cardiology at National Heart Lung and Blood Institute in Bethesda and in vascular biology at MIT. In 1993 he joined faculty at Harvard Medical School as an Assistant Professor of Medicine and rose through the ranks to become an Associate Professor of Medicine, Director of the Morse Coronary Care Unit and Director of Angiogenesis Research Center. In 2001 he was recruited to Dartmouth as AG Huber Professor of Medicine and Chief of Cardiology, subsequently becoming Director of Dartmouth Cardiovascular Center.

Dr. Simons’ research focuses on biology of arterial vasculature and spans basic, translational and clinical areas of investigations. He led the first trials of therapeutic angiogenesis in the USA and his basic research discoveries have played an important role in moving the field forward. Dr. Simons has an extensive track record of NIH funding including multiple R01s and he has served as a Principal Investigator of the NHLBI SCOR program in endothelial biology. Recently, he has been awarded a Leducq Transatlantic network grant to build and lead the ARTEMIS arteriogenesis network composed of investigators in USA, UK, Belgium and France. Dr. Simons also leads an NHLBI PPG program focused on arteriogenessi. He has published over 270 research papers and reviews and has been elected to a number of honorary societies including Association of American Physicians, American Society of Clinical Investigations and Association of University Cardiologists. He also a Fellow of the American Heart Association, American College of Cardiology and the American Society of Physiology.

Education & Training

MD Yale University (1984)
BS Massachusetts Institute of Technology (1980)
Postdoctoral Fellow MIT, Boston, Massachusetts
Fellow Beth Israel Hospital, Boston, Massachusetts
Postdoctoral Fellow National Heart Lung and Blood Institute at National Institutes of Health, Bethesda, Maryland
Resident New England Medical Center, Boston, Massachusetts

Honors & Recognition

  • Honorary Fellow, University College LondonUCL (2011)

  • Member, The Interurban Clinical ClubICC (2010)

  • Member, Association of American PhysiciansAAP (2005)

  • Member, Association of University CardiologistsAUC (2004)

  • Fellow, American Physiological SocietyAPS (2002)

  • Honorary CitationCardiovascular Society of India (1999)

  • Fellow, American Heart AssociationAHA (1998)

  • Member, American Society for Clinical InvestigationASCI (1998)

  • Honorary citationJapanese Circulation Society (1995)

Professional Service

  • Yale University (2010 - 2012) Provost’s Committee on cooperative research

  • NIH/SEP (2009) grant review

  • Yale University School of Medicine (2008 - 2012) Steering Committee, Vascular Biology and Therapeutics

  • North American Vascular Biology Association (NAVBO) (2005 - 2006) President

  • NIH/VCMB (2003 - 2007) Grant review panel


  • YALE-UCL Collaborative London, United Kingdom (2011)

    Dr. Simons is on the Joint Strategy Committee for the Yale-UCL Collaborative, an alliance which will provide opportunities for high-level scientific research, clinical and educational collaboration across the institutions involved: Yale University, Yale School of Medicine, Yale-New Haven Hospital...

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Contact Info

Michael Simons, MD, FACC, FAHA
Lab Location
300 George Street, Ste 7th floor
New Haven, CT 06511
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Mailing Address
Cardiovascular MedicinePO Box 208017
333 Cedar Street

New Haven, CT 06520-8017

Simons Lab