- Bender - Jin
- Mani - Yu
My laboratory has had a longstanding interest in inflammation and immunity, as they relate to vascular physiology and pathology.
We are interested in studying novel endothelial and vascular smooth muscle cell signaling pathways that are either disrupted or activated in the context of pulmonary arterial hypertension (PAH), a rare disease with high mortality (up to 45% at three years after diagnosis).
My laboratory studies vascular and lymphatic development, with particular emphasis on mechanisms that direct patterning and guidance.
The overall theme of Dr. Goldstein’s laboratory is how inflammation impacts different disease states.
My laboratory investigates blood vessel morphogenesis, the maintenance of the adult blood vessel and diseases of the vasculature.
A primary interest of our laboratory is to understand, at the cellular and molecular level, the events leading to blood vessel formation.
The goals of the Hwa laboratory are to decipher the roles played by the prostacyclin and thromboxane receptors (both G-protein coupled receptors) in the development of atherothrombosis.