A closer look at the impact of COVID-19 on cardio-oncology
In response to the COVID-19 pandemic, Lauren Baldassarre, MD, and members of the Cardio-Oncology and Imaging Councils of the American College of Cardiology shared recommendations regarding the cardiovascular care of COVID-19-positive patients.
Questions raised over cancer drugs in FDA's accelerated approval program
Many cancer patients and oncologists may turn to the US Food and Drug Administration's accelerated approval program, which provides access to new cancer drugs faster -- especially when a life-threatening cancer needs swift treatment or relief.Source: CNN.com
Antiretroviral Therapy Crucial in Preventing non-Hodgkin Lymphoma, YSPH Study Reinforces
A research team led by the Yale School of Public Health has found that for people living with HIV/AIDS, both recent immunosuppression and prolonged HIV viremia play important and independent roles in the development of non-Hodgkin lymphoma.
Broad genetic testing for advanced lung cancer may not improve survival
Testing for dozens of genetic mutations in tumors of patients with a common form of advanced lung cancer did not appear to improve survival compared to routine genetic testing, a study led by Yale Cancer Center (YCC) scientists has found.
Gender advocacy leads to major recognition for Yale oncologist Pamela Kunz, MD
Pamela Kunz, MD, was recently recognized as the 2021 Woman Oncologist of the Year by Women Leaders in Oncology for her commitment to advancing diversity, equity, and inclusion (DEI) through her research, committee leadership, and talks. “My advocacy is what is being recognized,” Kunz said, “To have the award acknowledge my DEI efforts is really meaningful.”
Yale Cancer Center Study Shows New Drug Combinations Improve Outcomes for Patients With Advanced Lung Cancer
New findings from a large study led by researchers at Yale Cancer Center shows the addition of the drugs oleclumab or monalizumab to durvalumab improved progression-free survival for patients with locally advanced non-small cell lung cancer.
A World Without Cervical Cancer: Preventive Medicine publishes special issue to further global efforts to eliminate deadly disease
Recognizing the urgent public health issue concerning Cervical Cancer, the editorial team of Preventive Medicine is publishing a special issue titled “From Science to Action to Impact: Eliminating Cervical Cancer,” which outlines the required courses of action to eliminate cervical cancer featuring Yale's Dr. Linda Niccolai.
Jawless Lamprey Takes a Bite out of Oncogene Evolution
By carefully tracing the evolution of a select number of cancer-causing genes in a variety of species, the researchers evaluated which animals are — and are not — effective in gauging how an analogue of those genes in humans can lead to cancer. What they found is surprising: jawless fish such as lampreys share significant similarities in these certain genes compared to humans, while fruit flies do not.
New Immunotherapy Treatment for Lung Cancer
More than 200,000 people a year in the United States are diagnosed with non-small cell lung cancers, which make up about 80 percent of all lung cancers. Now, the results of a phase three clinical trial show the immunotherapy drug atezolizumab, also known as Tecentriq, improves survival.Source: ABC News 12
Breast Cancer: Cost-Effectiveness of Neoadjuvant-Adjuvant Treatment Strategies
In HER2-positive early stage (stage I-II) breast cancer, several different preoperative (also called neoadjuvant) chemotherapy options exist, each of these is associated with a different rate of complete eradication of cancer from the breast and lymph nodes (called pathologic complete response or pCR). Patients who experience pCR have excellent long term survival.Source: MedicalResearch.com
Treatment with Genetically Altered Viruses Targets and Destroys Ovarian Cancer in Mice
Researchers have successfully eliminated chemotherapy-resistant ovarian cancer cells in mice using a single injection of two viruses genetically combined and altered to be safe, leading to long-term survival and demonstrating a potential breakthrough treatment for women.