Professor of Surgery (Cardiac); Division Chief, Cardiac Surgery, Surgery
The Yale Heart Failure Program
Heart Transplantation and Mechanical Circulatory Support
The Yale Heart Transplantation and Mechanical Circulatory Support is one of the finest in the country and consistently among of the largest volume programs in the North East. Our program has worked to expand access to donations through methods such as “donation after cardiovascular death”, use of Hepatitis C NAT+ donors, and through desensitization efforts of patients highly sensitized to potential donor antigens. Our center implants the HeartMate 3 LVAD as both Destination Therapy and Bridge to Transplantation.
Disease Management
The Heart Failure Population Health Program is a clinical care network which extends across the Connecticut, managing almost 30 thousand patients. Our group utilizes a variety of technologies for monitoring the health of our heart failure patients in the community, and we have several Heart Failure clinics open to drive the medical care of patients with newly diagnosed heart failure or recent hospital admissions.
Heart Failure Research
Fellowship Training Program
Comprehensive Heart Failure Program
Led by Tariq Ahmad MD, MPH, the Comprehensive Heart Failure Program comprises of a number of out-patient and in-patient initiatives dedicated to producing high quality outcomes for all types of heart failure patients.
The Heart Failure Population Health Program is a clinical care network which extends across the Connecticut shoreline, from Greenwich in the west to New London in the east. Our group utilizes a variety of technologies for monitoring the health of our heart failure patients in the community, and we have several Heart Failure Disease Management clinics open to drive the medical care of patients with newly diagnosed heart failure or recent hospital admissions.
The Inherited Cardiomyopathy Program includes clinics staffed with clinicians whom are experts in diseases such as hypertrophic cardiomyopathy and arrhythmogenic cardiomyopathy. Cardiomyopathy clinics which focus on acquired disease such as cardiac sarcoidosis and cardiac amyloidosis also exist. Finally, directed by Robert Elder, MD, the Adult Congenital Heart Disease Program acts as a clinical care bridge for the pediatric patient with heart disease as they age and mature into adulthood.
Heart Failure Research
Directed by Jeffrey Testani, MD, MTR, members of our group are active in many forms investigational scientific and clinical research. Areas of interest include diuretic therapies - not only loop diuretics but also SGLT-2 inhibitors, digital tools to assess heart failure population risk and predicted patient outcomes, new medical therapies for hypertrophic cardiomyopathy and TTR cardiac amyloidosis, as well as endeavors to expand the heart transplant donor pool. Our investigators also have the opportunity to partner with the immense talent available through the Yale School of Medicine’s Center for Outcomes Research and Evaluation (CORE) and the Yale Cardiovascular Research Group.
We have made remarkable progress in medical and surgical therapies for patients living with heart failure.Tariq Ahmad, MD, MPH
Publications
2023
- Updates in Cardiorenal Syndrome.McCallum W, Testani JM. Med Clin North Am. 2023 Jul; 2023 Apr 15. PMID: 37258013.
- The importance of forward flow and venous congestion in diuretic response in acute heart failure: Insights from the ESCAPE trial.Eder M, Griffin M, Moreno-Villagomez J, Bellumkonda L, Maulion C, Asher J, Wilson FP, Cox ZL, Ivey-Miranda JB, Rao VS, Butler J, Borlaug BA, McCallum W, Ramos-Mastache D, Testani JM. Int J Cardiol. 2023 Jun 15; 2023 Apr 5. PMID: 37023862.
- Changes in training patterns and confidence to return to sport in United States collegiate athletes during the COVID-19 pandemic.Seligman E, Beasley MA, Christino MA, Miller PE, Kobelski G, Stracciolini A. Phys Sportsmed. 2023 Jun; 2022 Mar 8. PMID: 35209782.
- "Pouring Salt in the Wound" of Sodium Restriction in Acute Heart Failure.Cox ZL, Testani JM. J Card Fail. 2023 May 24; 2023 May 24. PMID: 37236502.
- SGLT2 inhibitors and Diuretics in Heart Failure: Clicking Reset on the Renal Volume Setpoint?Borlaug BA, Testani JM. Eur Heart J. 2023 May 23; 2023 May 23. PMID: 37220086.
- A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes.Wilson FP, Yamamoto Y, Martin M, Coronel-Moreno C, Li F, Cheng C, Aklilu A, Ghazi L, Greenberg JH, Latham S, Melchinger H, Mansour SG, Moledina DG, Parikh CR, Partridge C, Testani JM, Ugwuowo U. Nat Commun. 2023 May 17; 2023 May 17. PMID: 37198160.
- A Clerkship Story Told in 55 Words-Medical Student Perspectives.Watkins A, Kauffman K, Clark KM, Sexton KW, Krum JM, Lara SW. Mil Med. 2023 May 16. PMID: 36632792.
- Wearable-Triggered Ecological Momentary Assessments Are Feasible in People With Advanced Cancer and Their Family Caregivers: Feasibility Study from an Outpatient Palliative Care Clinic at a Cancer Center.Schuler T, King C, Matsveru T, Back M, Clark K, Chin D, Lilian R, Gallego B, Coiera E, Currow DC. J Palliat Med. 2023 May 3; 2023 May 3. PMID: 37134212.
- Prevalence of Baseline Cardiac Arrhythmias in Participants with Overweight or Obesity in Phase 1 Clinical Trials: Analysis of 24-Hour Holter Electrocardiogram Recordings.Skovgaard D, Haahr PM, Lester R, Clark K, Paglialunga S, Finer N, Friedrichsen MH, Hjerpsted JB, Engelmann MDM. J Clin Pharmacol. 2023 May; 2023 Jan 20. PMID: 36524539.
- The blunted loop diuretic response in acute heart failure is driven by reduced tubular responsiveness rather than insufficient tubular delivery. The role of furosemide urine excretion on diuretic and natriuretic response in acute heart failure.Biegus J, Zymliński R, Testani J, Fudim M, Cox ZL, Guzik M, Iwanek G, Hurkacz M, Raj D, Marciniak D, Ponikowska B, Ponikowski P. Eur J Heart Fail. 2023 Apr 11; 2023 Apr 11. PMID: 37042083.
Faculty
Associate Professor of Medicine (Cardiovascular Medicine); Chief, Heart Failure Program
Assistant Professor of Surgery (Cardiac); Director Mechanical circulatory support and ECMO, Cardiac Surgery; Associate Director Heart Transplant, Cardiac Surgery
Assistant Professor of Medicine (Cardiovascular Medicine)
Assistant Professor of Medicine (Cardiovascular Medicine)
Assistant Professor of Clinical Medicine; Physician Advisor, Yale-New Haven Hospital; Medical Director, Safety & Performance Improvement HVC; Co-Chair, Pharmacy & Therapeutics Anticoagulation & Cardiology Subcommittee; Associate Clinical Professor of Medicine, Yale School of Medicine
Assistant Professor; Medical Director Cardiac Transplantation and Mechanical Circulatory Support, Heart Failure Program; Co Director Hypertrophic Cardiomyopathy Program, Cardiomyopathy & Inherited Cardiovascular Disease Program
Associate Professor of Medicine; Director of Heart Failure Research, Cardiovascular Medicine; Co-Director Heart & Vascular Center Clinical Research, Heart & Vascular Center
Robert W. Berliner Professor of Medicine (Cardiology); Chief, Cardiovascular Medicine; Chief, Cardiovascular Medicine, Yale New Haven Hospital; Physician-in-Chief, Heart and Vascular Center, Yale New Haven Health; Deputy Director, Clinical Trials Innovation, Yale Center for Clinical Investigation (YCCI); Co-Chair, Clinical and Translational Research Oversight Committee; President’s contingency planning committee, Clinical Practice/Clinical Research Subcommittee