Arya Mani, MD, FACC, FAHA

Professor of Medicine (Cardiology) and of Genetics; Director, Cardiovascular Genetics Program; Director, Cardiovascular Module

Physician Biography

As the Director of the Cardiovascular Genetics Program at Yale, I run a weekly outpatient clinic where I am involved in evaluation and management of patient with inherited cardiovascular diseases, supervision of the cardiovascular genetic counselor in providing consult to patients with inherited cardiovascular disease and in genetic testing, data analysis and diagnosis of the genetic disorder in these patients. I have established the first center for center for comprehensive testing of disease genes using the state of the art technology known as whole exome sequencing. We evaluate patients with inherited arrhythmias, sudden cardiac death, Long QT syndrome, Brugada, Cardiomyopathy, inherited aortic diseases, coronary artery disease and lipid abnormalities and many other inherited heart disease. We also manage the therapy of patients with lipid disorder, metabolic syndrome and coronary artery disease. We are the only center that has identified the cause of hereditary metabolic syndrome.

Clinical Interests

  • Adult
  • Cardiology
  • Cardiovascular Diseases
  • Cholesterol
  • Diabetes Mellitus
  • Diabetes Mellitus, Type 1
  • Diabetes Mellitus, Type 2
  • Echocardiography
  • Electrocardiography
  • Genetic Counseling
  • Genetics
  • Heart Defects, Congenital
  • Heart Diseases
  • Heart Failure
  • Heart Valve Diseases
  • Hypertension
  • Mitral Valve Prolapse
  • Syncope
  • Electrocardiography, Ambulatory
  • Inheritance Patterns
  • Atherosclerosis

Patient Care

Accepts new patients? Yes
Patient Type: Adult
Referrals: From patients or physicians

Patient Care Organizations

Internal Medicine: Cardiovascular Medicine: Cardiac Advanced Imaging Program; Cardiomyopathy & Inherited Cardiovascular Disease Program; Cardiovascular Genetics Program | Liver Center


Heart & Vascular Center, Yale-New Haven Hospital

Yale Medicine

Office of Cooperative Research

Board Certifications

  • Nuclear Cardiology The Certification Board of Nuclear Cardiology (2000)

  • Cardiovascular Disease AB of Internal Medicine (2001)

  • Adult Transthoracic Plus Stress Echocardiography National Board of Echocardiography (2008)

Clinical Trials

Conditions Study Title
Diseases of the Cardiovascular System aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation (aMAZE)

Edit this profile

Contact Info

Arya Mani, MD, FACC, FAHA
Patient Care Locations
Yale Nuclear CardiologyYale New Haven Hospital
20 York Street

New Haven, CT 06510
View on map...
Yale CardiologyYale Physicians Building
800 Howard Avenue, Ste 2nd floor

New Haven, CT 06519
View on map...
Lab Location
Mani's Lab300 George Street, Ste 759
New Haven, CT 06511
View on map...
Mailing Address
Cardiovascular MedicinePO Box 208056
333 Cedar Street

New Haven, CT 06520-8056