The Section of Allergy and Clinical Immunology includes a team whose focus is allergic and immunologic diseases. Our physicians are board certified in Allergy and Clinical Immunology. Management of complicated cases are discussed during weekly conferences, and Yale physicians are connected with a worldwide network that includes the foremost experts in allergy and clinical immunology.
Among the conditions we treat are the following:
- Allergic rhinoconjunctivitis (nasal and eye allergies)
- Urticaria (hives)
- Medication allergy
- Chronic sinusitis
- Hereditary angioneurotic edema
- Common variable immunodeficiency
- Secondary immune deficiencies
Among the treatments we offer are the following:
- Allergen vaccine immunotherapy (“allergy shots”)
- Asthma environmental controls and pharmacological controller therapy
- Intensive antihistamine regimens
- Biological therapy for hereditary angioneurotic edema
- Intravenous and subcutaneous immunoglobulin replenishment
- Aspirin desensitization
- Desensitization to antibiotics and other medications
Associate Professor of Medicine (Immunology) and of Pediatrics (Immunology)
Chief, Section of Allergy and Clinical Immunology
Research Interests:Characterization of molecular and cellular mechanisms in the pathogenesis of atopic dermatitis; Development of asthma; Atopic March; Using transgenic animal models; Th2 cytokine IL-13 as a potent inducer of phenotypical features of atopic dermatitis in mice, eosinophil, mast cell, and T cell infiltration, fibrotic and vascular remodeling, and clinical manifestations; IL-13 induced atopic dermatitis; Enhanced susceptibility of these mice to allergen induced allergic asthma in the lung; Identifying novel molecules and pathways in the pathogenesis of atopic dermatitis and the atopic march; Developing new therapeutics for allergic diseases
Clinical Interests:Adverse reactions to food and drugs, allergic conjunctivitis, allergic rhinitis, anaphylaxis, angioedema, asthma, eczema (atopic dermatitis), eosinophilia, hives (urticaria), insect sting allergy, mastocytosis, nasal polyposis, non-AIDS-related deficiencies of the immune system, sinusitis.
Clinician - Internal Medicine (Immunology)
Clinical Interests:Allergic rhinitis; asthma; food allergy; drug allergy; urticaria (hives); angioedema (hereditary and idiopathic); anaphylaxis; common variable immune deficiency (CVID); eosinophilic disorders (EGID and hypereosinophilic syndromes). Patients interested in comprehensive allergy testing (environmental, food or drug allergy) are best seen at the North Haven office (203-287-6200). Dr. Hsu provides aspirin desensitization to patients with aspirin-sensitive asthma with nasal polyps (aka aspirin-exacerbated respiratory disease or Samter's triad) at the Winchester Chest Clinic (203-785-4198). Patients with asthma, hives, angioedema (allergic swelling), or needing evaluation for immune deficiency may be seen at either location.
Paul B. Beeson Professor of Medicine (Immunology)
Research Interests:Host parasite relationship in Lyme Borreliosis; immune relationship between Borrelia burgdorferi and the host in chronic infection
Clinical Interests:Vasculitis; immunodeficiency; allergic rhinitis and asthma; systemic anaphylaxis
Clinical Instructor in Pediatrics (Immunology) and Residential College Associate Fellow in Faculty of Arts and Sciences
Clinical Interests:immune deficiency, urticaria and angioedema, drug allergy, food allergy, allergy skin testing, asthma, allergy vaccine immunotherapy
Instructor in Medicine (Immunology) and in Pediatrics (Immunology)
Research Interests:Immune Deficiency in Autoimmunity
Clinical Interests:Immunodeficiency including common variable immune deficiency (CVID); selective antibody deficiency and secondary immune deficiency; urticaria (hives); allergic rhinitis and asthma; systemic anaphylaxis; food allergy; drug allergy.
Assistant Professor of Pediatrics (Immunology)
Research Interests:Molecular mechanisms of primary immune deficiency diseases, Autoimmune manifestations of Common Variable Immune Deficiency, Smith-Magenis Syndrome related immune deficiency, Newborn screening for immune deficiency
Clinical Interests:The Diagnosis and Management of Inherited Immune Deficiency diseases including: Severe Combined Immune Deficiency, Hyper-IgM syndromes, Hyper-IgE syndromes, 22q11.2 deletion syndrome (DiGeorge or VCF Syndrome), Wiskott-Aldrich Syndrome, Chronic Mucocutaneuos Candidiasis, X-linked Agammaglobulinemia, Common Variable Immune deficiency, Smith-Magenis Syndrome related immune deficiency, Complement Deficiency, Chronic Granulomatous Disease, Leukocyte Adhesion Defects, Deficiencies of the Innate Immune System. The Diagnosis and Management of Auto-inflammatory Diseases (periodic fever syndromes) including Familial Mediterranean Fever (FMF), Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS), Deficiency of the Interleukin-1 Receptor Antagonist (DIRA) and Cryopyrin-Associated Periodic Syndromes (CAPS).